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Research progress on extracellular vesicles in chronic obstructive pulmonary disease
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Hang-Bin Zheng1, Guang-Lan Xu2, *, Guo-Sheng Li2, Yuan-Ling Li1, Yi-Hui Guo1
Medical Journal of Chinese People’s Liberation Army | 2023, 48(2) : 231 - 236
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Medical Journal of Chinese People’s Liberation Army | 2023, 48(2): 231-236
• Review •
Research progress on extracellular vesicles in chronic obstructive pulmonary disease
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Hang-Bin Zheng1, Guang-Lan Xu2, *, Guo-Sheng Li2, Yuan-Ling Li1, Yi-Hui Guo1
Affiliations
  • 1Graduate School, Guangxi University of Chinese Medicine, Nanning, Guangxi 530001, China
  • 2Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, Guangxi 530023, China
Published: 2023-02-28 doi: 10.11855/j.issn.0577-7402.2023.02.0231
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Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by airway inflammation,lung tissue destruction and airflow limitation associated with airway remodeling. As an important form of cellular communication,extracellular vesicles (EVs) are capable of selectively transmitting signals to nearby or distant cells to regulate their function and phenotype, and thought to play an indispensable role in lung disease. EVs can be released by bronchial epithelial cells, lymphocytes,neutrophils, macrophages, vascular endothelial cells and mesenchymal stem cells upon activation or apoptosis under specific conditions. The role of EVs derived from these cells in the pathogenesis and progression of COPD is reviewed in present paper for contributing a more comprehensive and detailed understanding of the role of EVs in the complex pathophysiology of COPD.

extracellular vesicles  /  chronic obstructive pulmonary disease  /  biomarkers
郑杭彬, 许光兰, 李国生, 李愿玲, 郭一慧. 细胞外囊泡在慢性阻塞性肺疾病中的作用研究进展. 解放军医学杂志, 2023 , 48 (2) : 231 -236 . DOI: 10.11855/j.issn.0577-7402.2023.02.0231
Hang-Bin Zheng, Guang-Lan Xu, Guo-Sheng Li, Yuan-Ling Li, Yi-Hui Guo. Research progress on extracellular vesicles in chronic obstructive pulmonary disease[J]. Medical Journal of Chinese People’s Liberation Army, 2023 , 48 (2) : 231 -236 . DOI: 10.11855/j.issn.0577-7402.2023.02.0231
Funding
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  • National Natural Science Foundation of China(81760848)
Appendix
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Year 2023 volume 48 Issue 2
641
305
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Article Info
doi: 10.11855/j.issn.0577-7402.2023.02.0231
  • Receive Date：2021-09-29
  • Online Date：2025-12-03
  • Published：2023-02-28
Article Data
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History
  • Received：2021-09-29
  • Accepted：2021-11-19
Funding
National Natural Science Foundation of China(81760848)
Affiliations
    1Graduate School, Guangxi University of Chinese Medicine, Nanning, Guangxi 530001, China
    2Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, Guangxi 530023, China

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表12种不同金属材料的力学参数
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Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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