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Research progress on extracellular vesicles in chronic obstructive pulmonary disease
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Hang-Bin Zheng1, Guang-Lan Xu2, *, Guo-Sheng Li2, Yuan-Ling Li1, Yi-Hui Guo1
Medical Journal of Chinese People’s Liberation Army | 2023, 48(2) : 231 - 236
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Medical Journal of Chinese People’s Liberation Army | 2023, 48(2): 231-236
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Research progress on extracellular vesicles in chronic obstructive pulmonary disease
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Hang-Bin Zheng1, Guang-Lan Xu2, *, Guo-Sheng Li2, Yuan-Ling Li1, Yi-Hui Guo1
Affiliations
  • 1Graduate School, Guangxi University of Chinese Medicine, Nanning, Guangxi 530001, China
  • 2Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, Guangxi 530023, China
Published: 2023-02-28 doi: 10.11855/j.issn.0577-7402.2023.02.0231
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Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by airway inflammation,lung tissue destruction and airflow limitation associated with airway remodeling. As an important form of cellular communication,extracellular vesicles (EVs) are capable of selectively transmitting signals to nearby or distant cells to regulate their function and phenotype, and thought to play an indispensable role in lung disease. EVs can be released by bronchial epithelial cells, lymphocytes,neutrophils, macrophages, vascular endothelial cells and mesenchymal stem cells upon activation or apoptosis under specific conditions. The role of EVs derived from these cells in the pathogenesis and progression of COPD is reviewed in present paper for contributing a more comprehensive and detailed understanding of the role of EVs in the complex pathophysiology of COPD.

extracellular vesicles  /  chronic obstructive pulmonary disease  /  biomarkers
Hang-Bin Zheng, Guang-Lan Xu, Guo-Sheng Li, Yuan-Ling Li, Yi-Hui Guo. Research progress on extracellular vesicles in chronic obstructive pulmonary disease[J]. Medical Journal of Chinese People’s Liberation Army, 2023 , 48 (2) : 231 -236 . DOI: 10.11855/j.issn.0577-7402.2023.02.0231
Funding
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  • National Natural Science Foundation of China(81760848)
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Year 2023 volume 48 Issue 2
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Article Info
doi: 10.11855/j.issn.0577-7402.2023.02.0231
  • Receive Date：2021-09-29
  • Online Date：2025-12-03
  • Published：2023-02-28
Article Data
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History
  • Received：2021-09-29
  • Accepted：2021-11-19
Funding
National Natural Science Foundation of China(81760848)
Affiliations
    1Graduate School, Guangxi University of Chinese Medicine, Nanning, Guangxi 530001, China
    2Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, Guangxi 530023, China

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小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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