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Current state of research on immunosupportive treatment of infection after liver transplantation
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Cong-Lin Wang1, 2, Sheng-Hua Xiao3, Jing-Jing Ji1, 2, Zhi-Feng Liu1, *
Medical Journal of Chinese People’s Liberation Army | 2023, 48(3) : 323 - 330
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Medical Journal of Chinese People’s Liberation Army | 2023, 48(3): 323-330
• Review •
Current state of research on immunosupportive treatment of infection after liver transplantation
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Cong-Lin Wang1, 2, Sheng-Hua Xiao3, Jing-Jing Ji1, 2, Zhi-Feng Liu1, *
Affiliations
  • 1Department of MICU, General Hospital of Southern Theatre Command, Guangzhou, Guangdong 510010, China
  • 2Guangzhou Key Laboratory of Geriatric Infection and Organ Function Support, General Hospital of Southern Theatre Command, Guangzhou, Guangdong 510010, China
  • 3Department of ICU, General Hospital of Southern Theatre Command, Guangzhou, Guangdong 510010, China
Published: 2023-03-28 doi: 10.11855/j.issn.0577-7402.2023.03.0323
Outline
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Liver transplantation is currently an effective treatment for end-stage liver disease. Postoperative infection is the main important cause of death in patients after liver transplantation. Due to the lack of specificity of clinical symptoms of postoperative infections, further insight is needed into the incidence, risk factors, diagnosis and treatment of different infections, including bacterial, fungal and viral. In addition, it could reduce the perioperative mortality that understanding the characteristics of changes in immune function after liver transplantation and timely prevention and treatment of post-transplant complications of infection, which would ultimately improve the outcome of patients. Nowadays, the use of immune-supporting drugs such as thymosin α1, intravenous immunoglobulin and ulinastatin have also shown some efficacy in patients with post-transplant infections.This article reviews the characteristics of infection, the changes of immune function and the feasibility of immunosupportive therapy after liver transplantation.

liver transplantation  /  infection  /  immune monitoring  /  immunological support
Cong-Lin Wang, Sheng-Hua Xiao, Jing-Jing Ji, Zhi-Feng Liu. Current state of research on immunosupportive treatment of infection after liver transplantation[J]. Medical Journal of Chinese People’s Liberation Army, 2023 , 48 (3) : 323 -330 . DOI: 10.11855/j.issn.0577-7402.2023.03.0323
Funding
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  • National Natural Science Foundation of China(82072143)
  • Natural Science Foundation of Guangdong Province(2021A1515010170)
Appendix
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Year 2023 volume 48 Issue 3
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Article Info
doi: 10.11855/j.issn.0577-7402.2023.03.0323
  • Receive Date：2021-11-17
  • Online Date：2025-12-03
  • Published：2023-03-28
Article Data
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History
  • Received：2021-11-17
  • Accepted：2022-04-16
Funding
National Natural Science Foundation of China(82072143)
Natural Science Foundation of Guangdong Province(2021A1515010170)
Affiliations
    1Department of MICU, General Hospital of Southern Theatre Command, Guangzhou, Guangdong 510010, China
    2Guangzhou Key Laboratory of Geriatric Infection and Organ Function Support, General Hospital of Southern Theatre Command, Guangzhou, Guangdong 510010, China
    3Department of ICU, General Hospital of Southern Theatre Command, Guangzhou, Guangdong 510010, China

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Citations
表12种不同金属材料的力学参数
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Family		 属数
Number of
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Number of
species		 占总种数比例
Percentage of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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