Military traumatic brain injury (TBI) belongs to military psychiatry, which is a new subcategory of psychiatry. Military TBI has become a landmark injury in modern military conflicts, which not only has a high incidence and death rate, but also has many sequelae, bringing heavy burden to patients and society. There have been frequent reports on TBI, but the pathophysiological mechanism of trauma to human brain tissue caused by military action and war has not been extensively studied. In this paper, epidemiological data, pathogenesis, molecular biological diagnosis and research achievements of existing therapeutic techniques related to TBI were reviewed, especially in terms of pathophysiological mechanism, and the pathogenesis, pathophysiological changes, blood-brain barrier injury, neuroinflammation and immune response of military TBI induced concussion and impact brain injury were summarized. It will provide useful reference for further study of military TBI.