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Research progress on phenotyping of adult sepsis
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Hai-Lun Peng1, Yue-Li Zhao2, Chong-Xiao Xu1, Guo-Dong Lin3, *, Zhi-Guo Pan2, 3, *
Medical Journal of Chinese People’s Liberation Army | 2023, 48(9) : 1107 - 1112
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Medical Journal of Chinese People’s Liberation Army | 2023, 48(9): 1107-1112
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Research progress on phenotyping of adult sepsis
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Hai-Lun Peng1, Yue-Li Zhao2, Chong-Xiao Xu1, Guo-Dong Lin3, *, Zhi-Guo Pan2, 3, *
Affiliations
  • 1First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China
  • 2Graduate School, Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong 510006, China
  • 3Department of Critical Care Medicine, General Hospital of Southern Theatre Command of People's Liberation Army, Guangzhou, Guangdong 510010, China
Published: 2023-09-28 doi: 10.11855/j.issn.0577-7402.1426.2022.0915
Outline
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Sepsis is a serious disease with high incidence and mortality. The pathogenesis, clinical manifestations, and multiple organ dysfunction of sepsis are complex and diverse, and this high heterogeneity leads to many challenges in the treatment of sepsis. The ideal treatment of sepsis should be based on its subphenotypes and targeted to the specific one. This review summarizes the research progress on phenotyping of adult sepsis from the relevant definitions, research methods, existing subtypes (such as based on molecular mechanism, pathophysiological mechanism, clinical manifestations, etc.), and the possible new subtypes in the future. We expect to flash a light on the discovery of new subtypes and the basic clinical research for the treatment of septic subtypes through this paper.

sepsis  /  septic shock  /  phenotyping  /  machine learning
Hai-Lun Peng, Yue-Li Zhao, Chong-Xiao Xu, Guo-Dong Lin, Zhi-Guo Pan. Research progress on phenotyping of adult sepsis[J]. Medical Journal of Chinese People’s Liberation Army, 2023 , 48 (9) : 1107 -1112 . DOI: 10.11855/j.issn.0577-7402.1426.2022.0915
  • National Natural Science Foundation of China(81873116)
Year 2023 volume 48 Issue 9
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Article Info
doi: 10.11855/j.issn.0577-7402.1426.2022.0915
  • Receive Date:2022-06-27
  • Online Date:2025-11-25
  • Published:2023-09-28
Article Data
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History
  • Received:2022-06-27
  • Accepted:2022-07-05
Funding
National Natural Science Foundation of China(81873116)
Affiliations
    1First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China
    2Graduate School, Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong 510006, China
    3Department of Critical Care Medicine, General Hospital of Southern Theatre Command of People's Liberation Army, Guangzhou, Guangdong 510010, China

Corresponding:

Pan Zhi-Guo, E-mail:
Lin Guo-Dong, E-mail:
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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