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When refractory diarrhea comes on, it greatly affects the life and daily work of patients, and there is no unified treatment. Patients with refractory diarrhea have varying degrees of intestinal flora disorder, so rebuilding the intestinal micro ecosystem may be an effective way to treat refractory diarrhea. Fecal microbiota transplantation (FMT) has the potential to be an effective treatment for refractory diarrhea as a therapy that reconstructs normal intestinal flora. In recent years, FMT has been applied to the treatment of some refractory diarrhea related to intestinal flora imbalance, such as recurrent clostridium difficile infection, inflammatory bowel disease, irritable bowel syndrome, and has achieved good results, but some problems have not been properly solved so far. This article reviews the mechanism of action of FMT in the treatment of refractory diarrhea, its clinical application, research progress and current problems.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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