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Sonogenetics is an emerging synthetic biology technique that uses sound waves to activate mechanosensitive ion channel proteins on the cell surface to regulate cell behavior and function. Due to the widespread presence of mechanically sensitive ion channel systems in cells and the advantages of non-invasion, strong penetrability, high safety and high accuracy of sonogenetics technology, it has great development potential in basic biomedical research and clinical applications, especially in neuronal regulation, tumor mechanism research, sonodynamic therapy and hearing impairment. This review discusses the basic principles of sonogenetics, the development status of sonogenetics and its application in the prevention and treatment of noise-induced hearing loss, summarizes and analyzes the current challenges and future development direction, thus providing a reference for further research and development of sonogenetics in the field of military medicine.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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