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Clinical management strategies for non-functional pituitary adenomas
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Qian Xu, Xiang Han, Jing Zhao, Hai-Bing Ju*
Medical Journal of Chinese People’s Liberation Army | 2024, 49(11) : 1259 - 1265
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Medical Journal of Chinese People’s Liberation Army | 2024, 49(11): 1259-1265
Special Issue on Diagnosis, Treatment and Management of Pituitary Diseases
Clinical management strategies for non-functional pituitary adenomas
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Qian Xu, Xiang Han, Jing Zhao, Hai-Bing Ju*
Affiliations
  • Department of Endocrinology, 920th Hospital of Joint Logistics Support Force of Chinese PLA, Kunming, Yunnan 650032, China
Published: 2024-11-28 doi: 10.11855/j.issn.0577-7402.0048.2024.0909
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Non-functional pituitary adenomas (NFPAs) are relatively common intracranial sellar tumors. The diagnostic rate of NFPAs has significantly increased in recent years due to the widespread application of computed tomography (CT) and magnetic resonance imaging (MRI) in clinical practice. NFPAs do not exhibit increased biochemical hormone secretion, so they may not present with obvious clinical manifestations. However, as the tumor grows, it can cause mass effect symptoms, such as headache, visual impairment, and related pituitary target gland dysfunction, and even life-threatening pituitary stroke. The evaluation of pituitary function in patients with NFPAs and the selection of treatment plans require close collaboration and scientific management by a multidisciplinary team. The genetic and epigenetic mechanisms underlying the occurrence and development of NFPAs have not yet been fully elucidated. New treatment strategies may be developed through technologies such as whole-genome sequencing combined with chromatin structure analysis. This review systematically summarizes the research progress in epidemiology, histopathology, clinical diagnosis, treatment, and prognosis of NFPAs, aiming to provide reference and guidance for clinical management.

non-functional pituitary adenomas  /  pituitary function  /  transsphenoidal surgery  /  radiation therapy  /  dopamine receptor agonists
Qian Xu, Xiang Han, Jing Zhao, Hai-Bing Ju. Clinical management strategies for non-functional pituitary adenomas[J]. Medical Journal of Chinese People’s Liberation Army, 2024 , 49 (11) : 1259 -1265 . DOI: 10.11855/j.issn.0577-7402.0048.2024.0909
  • Yunnan Province Xingdian Talent Medical and Health Talent Project(XDYC-YLWS-2023-0098)
Year 2024 volume 49 Issue 11
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Article Info
doi: 10.11855/j.issn.0577-7402.0048.2024.0909
  • Receive Date:2024-01-12
  • Online Date:2025-11-20
  • Published:2024-11-28
Article Data
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History
  • Received:2024-01-12
  • Accepted:2024-07-14
Funding
Yunnan Province Xingdian Talent Medical and Health Talent Project(XDYC-YLWS-2023-0098)
Affiliations
    Department of Endocrinology, 920th Hospital of Joint Logistics Support Force of Chinese PLA, Kunming, Yunnan 650032, China

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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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