收藏切换
Research progress on the role of mesenchymal stem cells in regulating immune response for treatment of traumatic brain injury
收藏切换
PDF
Yang Gao1, He-Wei Qin1, 2, *, Dan-Dan Liu1
Medical Journal of Chinese People’s Liberation Army | 2024, 49(11) : 1327 - 1335
Less
收藏切换
Medical Journal of Chinese People’s Liberation Army | 2024, 49(11): 1327-1335
Review
Research progress on the role of mesenchymal stem cells in regulating immune response for treatment of traumatic brain injury
Full
Yang Gao1, He-Wei Qin1, 2, *, Dan-Dan Liu1
Affiliations
  • 1School of Rehabilitation Medicine, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China
  • 2Department of Rehabilitation Medicine, the Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan 450000, China
Published: 2024-11-28 doi: 10.11855/j.issn.0577-7402.0020.2024.0726
Outline
收藏切换

Traumatic Brain Injury (TBI) is a significant global cause of mortality and disability, severely compromising public health and quality of life. TBI can be divided into primary and secondary brain injuries according to pathological mechanism, with excessive infiltration of immune cells post-injury triggering neuroinflammation being one of the crucial mechanisms in the cascade of secondary brain injury. Currently, There is a lack of targeted therapeutic agents for TBI, and treatment mainly relies on symptomatic care. Mesenchymal stem cells (MSCs) have shown promising potential in the treatment of brain injury through their immune-modulatory properties, which can mediate immune responses to reduce neuroinflammation and repair nerve damage. The review summarizes the recent research progress on immune responses following TBI and the immune regulatory effects of MSCs, aiming to provide references for subsequent research and clinical applications.

traumatic brain injury  /  mesenchymal stem cells  /  immunomodulation  /  blood-brain barrier  /  action mechanism
Yang Gao, He-Wei Qin, Dan-Dan Liu. Research progress on the role of mesenchymal stem cells in regulating immune response for treatment of traumatic brain injury[J]. Medical Journal of Chinese People’s Liberation Army, 2024 , 49 (11) : 1327 -1335 . DOI: 10.11855/j.issn.0577-7402.0020.2024.0726
  • Central Plains Talent Program of Central Plains Youth Top Talent Project (Yu Zu Tong [2021] 44)
  • Henan Province TCM Top Talent Training Project Special Topic(2022ZYBJ15)
Year 2024 volume 49 Issue 11
PDF
248
108
Cite this Article
BibTeX
Article Info
doi: 10.11855/j.issn.0577-7402.0020.2024.0726
  • Receive Date:2024-01-06
  • Online Date:2025-11-20
  • Published:2024-11-28
Article Data
Affiliations
History
  • Received:2024-01-06
  • Accepted:2024-03-28
Funding
Central Plains Talent Program of Central Plains Youth Top Talent Project (Yu Zu Tong [2021] 44)
Henan Province TCM Top Talent Training Project Special Topic(2022ZYBJ15)
Affiliations
    1School of Rehabilitation Medicine, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China
    2Department of Rehabilitation Medicine, the Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan 450000, China

Corresponding:

References
Share
https://castjournals.cast.org.cn/joweb/jfjyxzz/EN/10.11855/j.issn.0577-7402.0020.2024.0726
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT