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Research progress in the pathogenesis of preeclampsia
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Jie Huang, Jian Han, Jian-Xin Guo, Ge Diao, Li Li*
Medical Journal of Chinese People’s Liberation Army | 2025, 50(3) : 351 - 357
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Medical Journal of Chinese People’s Liberation Army | 2025, 50(3): 351-357
• Review •
Research progress in the pathogenesis of preeclampsia
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Jie Huang, Jian Han, Jian-Xin Guo, Ge Diao, Li Li*
Affiliations
  • Department of Obstetrics and Gynecology, Daping Hospital, Army Medical University, Chongqing 400042, China
Published: 2025-03-28 doi: 10.11855/j.issn.0577-7402.0891.2024.1225
Outline
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Preeclampsia (PE) is a severe hypertensive disorder during pregnancy that seriously affects the health of pregnant women and fetuses. Currently, the treatment is merely symptomatic, with unsatisfactory efficacy and often resulting in an increased incidence of therapeutic preterm birth. An increasing number of studies on PE suggest that the "unitary" theory is no longer adequate to elucidate its pathogenesis. PE is regarded as a syndrome influenced by multiple factors, featuring a complex pathogenesis and the potential to affect multiple organs and systems. This review summarizes the latest advancements in the classification, etiology, pathogenesis, and research models (including animal and in vitro models) of PE, aiming to provide references for subsequent research and offer assistance in clinical prevention, screening, and treatment.

preeclampsia  /  pathogenesis  /  animal model  /  in vitro model
Jie Huang, Jian Han, Jian-Xin Guo, Ge Diao, Li Li. Research progress in the pathogenesis of preeclampsia[J]. Medical Journal of Chinese People’s Liberation Army, 2025 , 50 (3) : 351 -357 . DOI: 10.11855/j.issn.0577-7402.0891.2024.1225
Funding
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  • Military Family Planning Project(21JSZ03)
  • Military Family Planning Project(22JSZ01)
  • Natural Science Foundation of Chongqing(cstc2019jcyj-msxmX0449)
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Year 2025 volume 50 Issue 3
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Article Info
doi: 10.11855/j.issn.0577-7402.0891.2024.1225
  • Receive Date：2024-06-25
  • Online Date：2025-11-10
  • Published：2025-03-28
Article Data
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History
  • Received：2024-06-25
  • Accepted：2024-12-10
Funding
Military Family Planning Project(21JSZ03)
Military Family Planning Project(22JSZ01)
Natural Science Foundation of Chongqing(cstc2019jcyj-msxmX0449)
Affiliations
    Department of Obstetrics and Gynecology, Daping Hospital, Army Medical University, Chongqing 400042, China

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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
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Genus		 种数
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Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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