Home Journals Articles Updates About
CN
image
收藏切换
Research progress of transcriptomics sequencing technology in evaluating human endometrial receptivity
收藏切换
PDF
Li-Na Ma1, 2, Hai-Ning Qi1, Mei Liu1, Yang Liu3, Hang Ge4, Feng-Juan Lu4, Xiao-Ke Wu3, Ying Qin1, *
Medical Journal of Chinese People’s Liberation Army | 2025, 50(5) : 607 - 611
Less
收藏切换
Medical Journal of Chinese People’s Liberation Army | 2025, 50(5): 607-611
• Review •
Research progress of transcriptomics sequencing technology in evaluating human endometrial receptivity
Full
Li-Na Ma1, 2, Hai-Ning Qi1, Mei Liu1, Yang Liu3, Hang Ge4, Feng-Juan Lu4, Xiao-Ke Wu3, Ying Qin1, *
Affiliations
  • 1Department of Obsterics, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250014, China
  • 2Post Doctoral Station of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250000, China
  • 3Department of Gynecology, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China
  • 4Graduate School of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China
Published: 2025-05-28 doi: 10.11855/j.issn.0577-7402.1475.2024.0731
Outline
收藏切换

Good endometrial receptivity is an essential factor for embryo implantation, and gene expression in endometrial tissue during the window of implantation (WOI) is closely related to receptivity. Transcriptome sequencing technology enables the identification of gene expression profiles of endometrium during different menstrual phases, as well as microRNAs and long-chain non-coding RNA sequences involved in regulating gene expression. Combining this technology with bioinformatics analysis provides a better understanding of specific gene expression during the receptive period and offers technical support for studying its regulatory mechanism. Moreover, gene expression profiles of the endometrium during different menstrual phases hold significant clinical application value for accurately assessing endometrium receptivity in infertility patients and those with repeated implantation failure, thereby guiding individualized embryo transfer strategies. This review summarizes the progress of transcriptome sequencing in evaluating human endometrial receptivity and discusses future research directions. This review aims to understand the complex molecular mechanisms of endometrial receptivity formation and regulation from the transcriptional level, in order to improve the implantation rate of embryos in assisted reproductive technology and reduce the abortion rate.

endometrium  /  RNA sequencing  /  embryo transfer  /  endometrial receptivity
Li-Na Ma, Hai-Ning Qi, Mei Liu, Yang Liu, Hang Ge, Feng-Juan Lu, Xiao-Ke Wu, Ying Qin. Research progress of transcriptomics sequencing technology in evaluating human endometrial receptivity[J]. Medical Journal of Chinese People’s Liberation Army, 2025 , 50 (5) : 607 -611 . DOI: 10.11855/j.issn.0577-7402.1475.2024.0731
Funding
Less
  • National Key Research and Development Project of China(2019YFC1709500)
  • National Pilot Project of Clinical Cooperation between Traditional Chinese and Western Medicine for Major Difficult Diseases ([2018]No.3 of the State Office of Traditional Chinese Medicine)
  • Natural Science Foundation of Shandong Province(ZR2022MH321)
  • Key Project of TCM Science and Technology Project of Shandong Province(Z-2023075)
Appendix
Less
Year 2025 volume 50 Issue 5
PDF
320
146
Cite this Article
BibTeX
Article Info
doi: 10.11855/j.issn.0577-7402.1475.2024.0731
  • Receive Date：2023-11-09
  • Online Date：2025-10-29
  • Published：2025-05-28
Article Data
Affiliations
History
  • Received：2023-11-09
  • Accepted：2024-01-22
Funding
National Key Research and Development Project of China(2019YFC1709500)
National Pilot Project of Clinical Cooperation between Traditional Chinese and Western Medicine for Major Difficult Diseases ([2018]No.3 of the State Office of Traditional Chinese Medicine)
Natural Science Foundation of Shandong Province(ZR2022MH321)
Key Project of TCM Science and Technology Project of Shandong Province(Z-2023075)
Affiliations
    1Department of Obsterics, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250014, China
    2Post Doctoral Station of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250000, China
    3Department of Gynecology, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China
    4Graduate School of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China

Corresponding:

References
Share
https://castjournals.cast.org.cn/joweb/jfjyxzz/EN/10.11855/j.issn.0577-7402.1475.2024.0731
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House