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Research progress of cooling therapy for heat stroke
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Jin-Bao Zhao1, 2, Qian Wang3, Tian-Yu Xin1, Han-Ding Mao1, Ye Tao4, Bo Ning5, Zhen-Zhen Qin1, Shu-Yuan Liu1, *, Qing Song2, *
Medical Journal of Chinese People’s Liberation Army | 2025, 50(5) : 612 - 618
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Medical Journal of Chinese People’s Liberation Army | 2025, 50(5): 612-618
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Research progress of cooling therapy for heat stroke
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Jin-Bao Zhao1, 2, Qian Wang3, Tian-Yu Xin1, Han-Ding Mao1, Ye Tao4, Bo Ning5, Zhen-Zhen Qin1, Shu-Yuan Liu1, *, Qing Song2, *
Affiliations
  • 1Department of Emergency Medicine, the Sixth Medical Center of Chinese PLA General Hospital, Beijing 100048, China
  • 2Medical School of Chinese PLA, Beijing 100853, China
  • 3Department of Emergency, the Third Medical Center of Chinese PLA General Hospital, Beijing 100039, China
  • 4Out-patient Department of Huangsi, Jingzhong Medical Zone, Chinese PLA General Hospital, Beijing 100120, China
  • 5Department of Intensive Care Medicine, Air Force Medical Center, Beijing 100142, China
Published: 2025-05-28 doi: 10.11855/j.issn.0577-7402.0071.2024.1025
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Heat stroke is a heat-related illness caused by an imbalance between the body's heat production and heat dissipation, which could lead to multiple organ dysfunction syndrome with a high mortality rate. Rapid and effective reduction of core body temperature is key to successful treatment. This article reviews recent progress in the treatment of heat stroke, including new understandings of organ injury mechanisms, the timing, velocity and goals of cooling treatment, evaluation and selection of traditional cooling techniques (such as cold water immersion), and scientific evaluation of new cooling technologies (such as blood purification technology and intravascular heat exchange cooling technology), aiming to promote understanding and treatment of heat stroke.

heat stroke  /  organ injury  /  cooling  /  endovascular heat exchange cooling
Jin-Bao Zhao, Qian Wang, Tian-Yu Xin, Han-Ding Mao, Ye Tao, Bo Ning, Zhen-Zhen Qin, Shu-Yuan Liu, Qing Song. Research progress of cooling therapy for heat stroke[J]. Medical Journal of Chinese People’s Liberation Army, 2025 , 50 (5) : 612 -618 . DOI: 10.11855/j.issn.0577-7402.0071.2024.1025
Funding
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  • Special Project of Military Epidemic Prevention And Protection(22FYFH11)
  • Special Program of Innovation Project of Military Medicine(18CXZ019)
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Year 2025 volume 50 Issue 5
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Article Info
doi: 10.11855/j.issn.0577-7402.0071.2024.1025
  • Receive Date：2024-01-16
  • Online Date：2025-10-29
  • Published：2025-05-28
Article Data
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History
  • Received：2024-01-16
  • Accepted：2024-08-28
Funding
Special Project of Military Epidemic Prevention And Protection(22FYFH11)
Special Program of Innovation Project of Military Medicine(18CXZ019)
Affiliations
    1Department of Emergency Medicine, the Sixth Medical Center of Chinese PLA General Hospital, Beijing 100048, China
    2Medical School of Chinese PLA, Beijing 100853, China
    3Department of Emergency, the Third Medical Center of Chinese PLA General Hospital, Beijing 100039, China
    4Out-patient Department of Huangsi, Jingzhong Medical Zone, Chinese PLA General Hospital, Beijing 100120, China
    5Department of Intensive Care Medicine, Air Force Medical Center, Beijing 100142, China

Corresponding:

Liu Shu-Yuan, E-mail: ;
Song Qing, E-mail:
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小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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