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Research progress on cerebral blood flow changes after acute high-altitude exposure
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Xu GUAN, Rui ZHANG, Yang BIAN, Ziwei GUO, Jun WANG
Academic Journal of Chinese PLA Medical School | 2026, 47(6) : 674 - 678
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Academic Journal of Chinese PLA Medical School | 2026, 47(6): 674-678
• Review •
Research progress on cerebral blood flow changes after acute high-altitude exposure
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Xu GUAN, Rui ZHANG, Yang BIAN, Ziwei GUO, Jun WANG
Affiliations
  • Department of Neurointervention, Medical Department of Neurology, the First Medical Center, Chinese PLA General Hospital, Beijing 100089, China
Published: 2026-06-28 doi: 10.12435/j.issn.2095-5227.25122905
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Acute high-altitude exposure (AHE) imposes a significant stimulus on the human cerebrovascular system, resulting in abnormalities in cerebral blood flow (CBF). The abnormal changes in CBF are one of the current research hotspots. In a hypoxic environment, CBF, cerebrovascular compliance, and cerebral perfusion all undergo significant changes, which are closely related to an individual's neurocognitive function and adaptability. Existing studies indicate that there are still shortcomings in the relevant field, and it is urgent to further explore the regulation of CBF and its mechanisms, as well as to study the relative symptoms and the process by which they eventually lead to high-altitude encephalopathy. This article systematically summarizes the basic experimental and clinical studies on the effect of AHE on CBF,deeply discusses the mechanisms of changes in CBF, flow velocity, and the nervous system, as well as the interventional treatment methods for abnormal CBF, hoping to provide assistance for research in this field.

acute high-altitude exposure  /  cerebral hemodynamics  /  hypoxic adaptation  /  high-altitude encephalopathy  /  cerebral perfusion regulation  /  neurocognitive function
关旭, 张锐, 边洋, 郭子维, 王君. 急进高原脑血流变化的研究进展. 解放军医学院学报, 2026 , 47 (6) : 674 -678 . DOI: 10.12435/j.issn.2095-5227.25122905
Xu GUAN, Rui ZHANG, Yang BIAN, Ziwei GUO, Jun WANG. Research progress on cerebral blood flow changes after acute high-altitude exposure[J]. Academic Journal of Chinese PLA Medical School, 2026 , 47 (6) : 674 -678 . DOI: 10.12435/j.issn.2095-5227.25122905
Year 2026 volume 47 Issue 6
34
14
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doi: 10.12435/j.issn.2095-5227.25122905
  • Receive Date:2025-12-29
  • Online Date:2026-10-30
  • Published:2026-06-28
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  • Received:2025-12-29
Affiliations
    Department of Neurointervention, Medical Department of Neurology, the First Medical Center, Chinese PLA General Hospital, Beijing 100089, China

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WANG Jun.Email:
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表12种不同金属材料的力学参数
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小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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