Article(id=1220689490998379295, tenantId=1146029695717560320, journalId=1220038315760373764, issueId=1220689483859677846, articleNumber=null, orderNo=null, doi=10.12102/j.issn.1009-6493.2025.19.018, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=research-article, receivedDate=1741881600000, receivedDateStr=2025-03-14, revisedDate=1757347200000, revisedDateStr=2025-09-09, acceptedDate=null, acceptedDateStr=null, onlineDate=1768964653968, onlineDateStr=2026-01-21, pubDate=1760025600000, pubDateStr=2025-10-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1768964653968, onlineIssueDateStr=2026-01-21, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1768964653968, creator=13701087609, updateTime=1768964653968, updator=13701087609, issue=Issue{id=1220689483859677846, tenantId=1146029695717560320, journalId=1220038315760373764, year='2025', volume='39', issue='19', pageStart='3201', pageEnd='3376', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1768964652266, creator=13701087609, updateTime=1768965013333, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1220690998338961744, tenantId=1146029695717560320, journalId=1220038315760373764, issueId=1220689483859677846, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1220690998338961745, tenantId=1146029695717560320, journalId=1220038315760373764, issueId=1220689483859677846, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=3323, endPage=3325, ext={EN=ArticleExt(id=1220689493531739048, articleId=1220689490998379295, tenantId=1146029695717560320, journalId=1220038315760373764, language=EN, title=Status quo and influencing factors of serum 25 hydroxyvitamin D levels in infants and young children aged 0⁃3 years in Yuncheng city, columnId=1220689488284668633, journalTitle=Chinese Nursing Research, columnName=Comprehensive Study, runingTitle=null, highlight=null, articleAbstract=

Objective To investigate the serum 25⁃hydroxyvitamin D levels and influencing factors in infants and young children aged 0⁃3 years in Yuncheng city. Methods A total of 1 803 infants and young children who underwent physical examinations at Yuncheng Maternal and Child Health Hospital from June 2019 to June 2023 were selected as the research subjects.Venous blood was collected and serum 25⁃hydroxyvitamin D levels were detected by using an AB company high⁃performance liquid chromatography tandem mass spectrometer(AB4500).Univariate analysis was used to investigate the influencing factors of serum 25⁃hydroxyvitamin D levels. Results The serum 25⁃hydroxyvitamin D level of 1 803 infants and young children was(35.256±9.090) ng/mL.Univariate analysis results showed that maternal education level,feeding method,outdoor activity duration,age,and daily 25 hydroxyvitamin D supplementation dose had an impact on the serum 25 hydroxyvitamin D levels of infants and young children(P<0.05). Conclusions Serum 25 hydroxyvitamin D levels in infants and young children aged 0⁃3 years in Yuncheng city are low⁃normal.The higher the mother's education level,the more reasonable outdoor activities,timely addition of complementary foods,and reasonable supplementation of 25 hydroxyvitamin D are beneficial for the healthy growth of infants and young children.

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目的 旨在调查运城市0~3岁婴幼儿血清25⁃羟维生素D水平以及影响因素。 方法 选取2019年6月—2023年6月在运城市妇幼保健院体检的1 803名婴幼儿为研究对象，采集静脉血，使用美国AB公司高效液相色谱串联质谱仪（AB4500）检测血清25⁃羟维生素D水平。采用单因素分析婴幼儿血清25⁃羟维生素D水平的影响因素。 结果 1 803名婴幼儿血清25⁃羟维生素D为（35.256±9.090） ng/mL。单因素分析结果显示，母亲文化程度、喂养方式、户外活动时长、年龄、每日25⁃羟维生素D补充剂量对婴幼儿血清25⁃羟维生素D水平有影响（P<0.05）。 结论 运城市0~3岁婴幼儿血清25⁃羟维生素D处于正常偏低水平，母亲文化程度越高、合理户外活动、及时添加辅食、合理补充25⁃羟维生素D有利于婴幼儿健康成长。

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Univariate factor analysis results of influencing factors on serum 25⁃hydroxyvitamin D levels in infants and young children

, figureFileSmall=null, figureFileBig=null, tableContent=

项目	分类	人数	血清25⁃羟维生素D	P
年龄	1~6月	606	35.056±8.786	<0.05
	7~12月	626	36.397±8.940
	13~24月	326	35.318±9.233
	25~36月	245	32.359±7.561
性别	男	967	35.250±9.190	>0.05
	女	836	35.270±8.990
分娩方式	剖宫产	854	34.996±9.067	>0.05
	顺产	949	35.619±9.096
母亲文化程度	初中及以下	184	34.240±10.081	<0.05
	高中及专科	886	35.275±8.956
	本科及以上	733	35.876±8.695
喂养方式	纯母乳喂养	1 301	34.455±8.833	<0.05
	混合喂养	502	37.686±9.700
每日户外活动时长	<2 h	920	34.281±8.983	<0.05
	≥2 h	883	35.934±9.067
每日25⁃羟维生素D补充剂量	≤400 IU	736	34.524±8.362	<0.05
	400~800 IU	1 067	36.201±9.125

), ArticleFig(id=1220838938349060392, tenantId=1146029695717560320, journalId=1220038315760373764, articleId=1220689490998379295, language=CN, label=表1, caption=

婴幼儿血清25-羟维生素D水平影响因素的单因素分析结果 (ng/mL)

, figureFileSmall=null, figureFileBig=null, tableContent=

项目	分类	人数	血清25⁃羟维生素D	P
年龄	1~6月	606	35.056±8.786	<0.05
	7~12月	626	36.397±8.940
	13~24月	326	35.318±9.233
	25~36月	245	32.359±7.561
性别	男	967	35.250±9.190	>0.05
	女	836	35.270±8.990
分娩方式	剖宫产	854	34.996±9.067	>0.05
	顺产	949	35.619±9.096
母亲文化程度	初中及以下	184	34.240±10.081	<0.05
	高中及专科	886	35.275±8.956
	本科及以上	733	35.876±8.695
喂养方式	纯母乳喂养	1 301	34.455±8.833	<0.05
	混合喂养	502	37.686±9.700
每日户外活动时长	<2 h	920	34.281±8.983	<0.05
	≥2 h	883	35.934±9.067
每日25⁃羟维生素D补充剂量	≤400 IU	736	34.524±8.362	<0.05
	400~800 IU	1 067	36.201±9.125

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