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Preparation of Medium-Chain Fatty Acids (MCFA) Nano-Liposome by Means of High Pressure Microfluidization (HPM)
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Wei LIU, Wei-Lin LIU, Cheng-Mei LIU, Shui-Bing YANG, Hui-Juan ZHENG, Jian-Hua LIU, Jian-Hong WANG
Chinese Journal of High Pressure Physics | 2010, 24(4) : 293 - 299
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Chinese Journal of High Pressure Physics | 2010, 24(4): 293-299
Preparation of Medium-Chain Fatty Acids (MCFA) Nano-Liposome by Means of High Pressure Microfluidization (HPM)
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Wei LIU, Wei-Lin LIU, Cheng-Mei LIU, Shui-Bing YANG, Hui-Juan ZHENG, Jian-Hua LIU, Jian-Hong WANG
Affiliations
  • State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China
Published: 2010-08-15
Outline
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Medium-chain fatty acids (MCFA) nano-liposome was prepared and characterized by means of high pressure microfluidization (HPM), sonication and microfiltration, respectively. The average diameter, encapsulated efficiency and stability were investigated after treatment with different pressures and passes number. The results indicated that MCFA liposome prepared by HPM exhibited the smallest average diameter, the largest encapsulated efficiency and the best stability. The smallest average diameter of MCFA liposome could be achieved after a treatment of 6 passes at 120 MPa, with a value of (73.9±10.2) nm, while the encapsulated efficiency was (52.20±9.57)%. The largest encapsulated efficiency of (70.64±11.25)% and loaded efficiency of (9.42±0.83)% were obtained when treated 4 passes at 120 MPa, with an average diameter value of (78.9±21.5) nm. After being treated 4 passes, MCFA liposome exhibited the best stability, with a coefficient value of 0.999 0±3.695 1.

high pressure microfluidization (HPM)  /  nano-liposome  /  medium-chain fatty acids (MCFA)  /  average diameter  /  encapsulated efficiency  /  stability coefficient
刘伟, 刘玮琳, 刘成梅, 杨水兵, 郑会娟, 刘建华, 王建红. 高压微射流制备纳米中链脂肪酸脂质体的研究. 高压物理学报, 2010 , 24 (4) : 293 -299 .
Wei LIU, Wei-Lin LIU, Cheng-Mei LIU, Shui-Bing YANG, Hui-Juan ZHENG, Jian-Hua LIU, Jian-Hong WANG. Preparation of Medium-Chain Fatty Acids (MCFA) Nano-Liposome by Means of High Pressure Microfluidization (HPM)[J]. Chinese Journal of High Pressure Physics, 2010 , 24 (4) : 293 -299 .
Year 2010 volume 24 Issue 4
17
2
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Article Info
  • Receive Date:2009-06-20
  • Online Date:2026-11-02
  • Published:2010-08-15
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  • Received:2009-06-20
  • Revised:2009-09-29
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    State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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