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Optimization of Conditions to Sterilize Staphyloccus Aureus by Ultra-High Hydrostatic Pressure Using Response Surface Methodology
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Yu-Long GAO, Yun-Xiang WANG, Han-Hu JIANG
Chinese Journal of High Pressure Physics | 2004, 18(3) : 273 - 278
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Chinese Journal of High Pressure Physics | 2004, 18(3): 273-278
• Research Note •
Optimization of Conditions to Sterilize Staphyloccus Aureus by Ultra-High Hydrostatic Pressure Using Response Surface Methodology
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Yu-Long GAO, Yun-Xiang WANG, Han-Hu JIANG
Affiliations
  • College of Food Science and Technology, Nanjing Agriculture University, Nanjing 210095, China
Published: 2004-09-05
Outline
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The results of factorial experiment showed that the significant external factors affecting UHHP sterilization were pressure, temperature and pressure holding time. Based on the results, response surface methodology (RSM) was employed and a second order quadratic equation for UHHP sterilization was built in the present work. The applicability of the model equation for predicting the optimum response values was verified effectively by the validation data. By analyzing the response surface plots and their corresponding contour plots as well as solving the quadratic equation, the optimum process parameters for sterilization Staphyloccus aureus of six log cycles were obtained as: temperature 34.35 ℃, pressure 329.84 MPa, and pressure holding time15.53 min.

ultra-high hydrostatic pressure (UHHP) sterilization  /  Staphyloccus aureus  /  response surface methodology (RSM)  /  optimization
高瑀珑, 王允祥, 江汉湖. 响应曲面法优化超高压杀灭金黄色葡萄球菌条件的研究. 高压物理学报, 2004 , 18 (3) : 273 -278 .
Yu-Long GAO, Yun-Xiang WANG, Han-Hu JIANG. Optimization of Conditions to Sterilize Staphyloccus Aureus by Ultra-High Hydrostatic Pressure Using Response Surface Methodology[J]. Chinese Journal of High Pressure Physics, 2004 , 18 (3) : 273 -278 .
Year 2004 volume 18 Issue 3
23
4
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Article Info
  • Receive Date:2003-11-17
  • Online Date:2026-10-31
  • Published:2004-09-05
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  • Received:2003-11-17
  • Revised:2004-02-09
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    College of Food Science and Technology, Nanjing Agriculture University, Nanjing 210095, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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