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Preparation and In Vitro Bioactivity of Cerium-Incorporated Bioglass Microspheres via Spray Drying Method
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Baolong CHEN1, Yaping HU1, Min ZHU1, Yufang ZHU2
Journal of the Chinese Ceramic Society | 2023, 51(10) : 2527 - 2535
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Journal of the Chinese Ceramic Society | 2023, 51(10): 2527-2535
• Research Articles •
Preparation and In Vitro Bioactivity of Cerium-Incorporated Bioglass Microspheres via Spray Drying Method
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Baolong CHEN1, Yaping HU1, Min ZHU1, Yufang ZHU2
Affiliations
  • 1.School of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China
  • 2.Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China

    • CHEN Baolong (1997-), male, Master candidate. E-mail:

About Author:

CHEN Baolong (1997-), male, Master candidate. E-mail:

Published: 2023-08-04 doi: 10.14062/j.issn.0454-5648.20230189
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Bioglass (BG) microspheres with a constitution of CaO-SiO2-P2O5 demonstrate promising applications in bone repair. It has been proved that the cerium ion incorporation in bioglass structure can provide materials with additional antioxidant, anti-inflammatory and angiogenesis functions. In this study, cerium-incorporated bioglass (Ce-BG) microspheres were prepared via a spray drying process. The effects of Ce content on the phase composition, degradation performance and in vitro bioactivity of Ce-BG microspheres were investigated. The results show that all microspheres are uniform in element distribution with relatively smooth surfaces and a high degree of sphericity. The Ce incorporation introduces a small amount of CePO4 and CeO2 crystalline phases. Along with the increase of Ce content, the degradation rate of Ce-BG microspheres slows down, and the effect of degradation products on the increase of environmental pH value is alleviated, and the pH value was found to be the lowest after 7 d of immersion for Ce-BG microspheres with mole ratio of Ce and Ce+Ca of 0.03∶1.00 in Tris-HCl buffer. Ce-BG microspheres with different Ce content have good ability to induce apatite deposition in vitro.

bioglass  /  cerium  /  spray drying  /  microspheres
陈宝龙, 胡亚萍, 朱敏, 朱钰方. 喷雾干燥法制备含铈生物玻璃微球及其体外生物活性. 硅酸盐学报, 2023 , 51 (10) : 2527 -2535 . DOI: 10.14062/j.issn.0454-5648.20230189
Baolong CHEN, Yaping HU, Min ZHU, Yufang ZHU. Preparation and In Vitro Bioactivity of Cerium-Incorporated Bioglass Microspheres via Spray Drying Method[J]. Journal of the Chinese Ceramic Society, 2023 , 51 (10) : 2527 -2535 . DOI: 10.14062/j.issn.0454-5648.20230189
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Year 2023 volume 51 Issue 10
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Article Info
doi: 10.14062/j.issn.0454-5648.20230189
  • Receive Date：2023-03-27
  • Online Date：2026-10-19
  • Published：2023-08-04
Article Data
Affiliations
History
  • Received：2023-03-27
  • Revised：2023-05-10
Funding
Affiliations
    1.School of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China
    2.Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China

Corresponding:

ZHU Min (1985-), female, Ph.D., Associate Professor; E-mail:
ZHU Yufang (1976-), male, Professor.
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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