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Effect of Micro-Nano Bioactive Glass Content in Gelatin Based Composite Hydrogel on Its Mineralization and Degradation In Vitro
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Zhen YANG1, Cong LIU2, Xiaofeng CHEN2, Lei YANG1
Journal of the Chinese Ceramic Society | 2023, 51(10) : 2536 - 2543
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Journal of the Chinese Ceramic Society | 2023, 51(10): 2536-2543
• Research Articles •
Effect of Micro-Nano Bioactive Glass Content in Gelatin Based Composite Hydrogel on Its Mineralization and Degradation In Vitro
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Zhen YANG1, Cong LIU2, Xiaofeng CHEN2, Lei YANG1
Affiliations
  • 1.School of Materials Science and Engineering, Hebei University of Technology, Tianjin 300131, China
  • 2.School of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China

    • YANG Zhen (1993-), male, Ph.D. E-mail:

About Author:

YANG Zhen (1993-), male, Ph.D. E-mail:

Published: 2023-08-07 doi: 10.14062/j.issn.0454-5648.20230212
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In recent years, the composite hydrogels composed of micro-nano bioactive glass (MNBG) and gelatin are widely used in tissue regeneration. However, the relationship between hydrogels and MNBG in terms of mineralization and degradation is still unclear. In this paper, gelatin based composite hydrogels with different concentrations of MNBG were prepared, and the effect of MNBG on the mineralization and degradation properties of composite hydrogel was investigated by in vitro experiments. The results show that the composite hydrogel does not affect the bioactive ion release of MNBG, and the formation of negative curvature interface by a high concentration of MNBG aggregates is a necessary condition for composite hydrogels to mineralize. In addition, increasing the concentration of MNBG and quickly mineralizing to form hydroxyapatite layer can effectively reduce the degradation rate of gelatin based composite hydrogel.

micro-nano bioactive glass  /  composite hydrogel  /  in vitro mineralization  /  degradation
杨振, 刘聪, 陈晓峰, 杨磊. 明胶基复合水凝胶中微纳米生物活性玻璃含量对其体外矿化及降解性能的影响. 硅酸盐学报, 2023 , 51 (10) : 2536 -2543 . DOI: 10.14062/j.issn.0454-5648.20230212
Zhen YANG, Cong LIU, Xiaofeng CHEN, Lei YANG. Effect of Micro-Nano Bioactive Glass Content in Gelatin Based Composite Hydrogel on Its Mineralization and Degradation In Vitro[J]. Journal of the Chinese Ceramic Society, 2023 , 51 (10) : 2536 -2543 . DOI: 10.14062/j.issn.0454-5648.20230212
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Year 2023 volume 51 Issue 10
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Article Info
doi: 10.14062/j.issn.0454-5648.20230212
  • Receive Date：2023-04-01
  • Online Date：2026-10-19
  • Published：2023-08-07
Article Data
Affiliations
History
  • Received：2023-04-01
  • Revised：2023-04-17
Funding
Affiliations
    1.School of Materials Science and Engineering, Hebei University of Technology, Tianjin 300131, China
    2.School of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China

Corresponding:

CHEN Xiaofeng (1956-), male, Ph.D., Professor. E-mail:
YANG Lei (1982-), male, Ph.D., Professor.
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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