CHANG Dongbiao (1999-), male, Doctoral candidate. E-mail: Chang_db@163.com
The inorganic composition of natural bone tissue is mainly calcium phosphate and consists of a variety of other elements necessary to maintain life activities to ensure the normal growth and development of bone tissue. In the preparation of calcium phosphate biomaterials, elemental doping can effectively regulate the morphology of calcium phosphate and have antibacterial properties, immune regulation, angiogenesis, osteoinduction and other biological functions. This review represented the regulatory effects of single-doping or co-doping of Mg, Zn, Sr, Cu, Ag, Co, Ag, Mn, and rare earth elements as well as Se, Si, and F in a variety of calcium phosphate on the structural morphology and biological function of materials. In addition, the future research work of calcium phosphate biomaterials was also proposed to provide a reference for the future research of novel scaffolds in tissue engineering.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |