Latest ArticlesTraditional soft lithography based PDMS device fabrication requires complex procedures carried out in a clean room. Herein, we report a photolithography-free method that rapidly produces PDMS devices in 30 min. By using a laser cutter to ablate a tape, a male photoresist mold can be obtained within 5 min by a simple heating-step, which offers significant superiority over currently used photolithographybased method. Since it requires minimal energy to cut the tape, our fabrication strategy shows good resolution (~ 100 μm) and high throughput. Furthermore, the micro-mold height can be easily controlled by changing the tape types and layers. As a proof-of-concept, we demonstrated that the fabricated PDMS devices are compatible with biochemical reactions such as quenching reaction of KI to fluorescein and cell culture/staining. Collectively, our strategy shows advantages of low input, simple operation procedure and short fabrication time, therefore we believe this photolithography-free method could serve as a promising way for rapid prototyping of PDMS devices and be widely used in general biochemical laboratories.
In this work, the nano-g-C3N4/UiO-66-NH2 composite was prepared by one-step solvothermal method. The as-prepared composite was characterized by scanning electron microscopy, Brunner-Emmet-Teller measurement, energy dispersive spectrometer, X-ray diffraction, and Fourier transform infrared spectroscopy. By using nano-g-C3N4/UiO-66-NH2 composite as sorbent, a dispersive solid-phase extraction coupled with high-performance liquid chromatography was developed to sensitive analysis of food colorants including tartrazine, amaranth, carmine, sunset yellow, allura red and bright blue. The experiment parameters including the amount of sorbent, adsorption time, the pH of adsorption solution, desorption time, desorption solvent, the pH of desorption solution as well as the proportion between desorption solvent and buffer solvent were investigated. Under the optimized conditions, the limits of detection (S/N = 3) and limits of quantitation (S/N = 10) were determined in the ranges of 0.08–0.8 and 0.2–2.0 ng/mL, respectively. With the developed sample pretreatment method, carmine and brilliant blue were determined from blueberry juice by HPLC-DAD. The contents were calculated as 1.53 µg/mL and 0.17 µg/mL, respectively.
Photoelectrochemical (PEC) sensor is an emerging technology in analysis as the advantage of fast response, high sensitivity and uncomplicated operation. In this study, an effective label-free PEC sensor for bisphenol A (BPA) detecting is constructed, in which ZnIn2S4/g-C3N4 heterojunction is prepared via a simple hydrothermal method. The characterization outcomes display that the formation of p-n heterojunction helps for promoting the separation efficiency of photo-generated carrier. Under visible light irradiation, the ZnIn2S4/g-C3N4 modified electrode exhibits broader liner range from 0.05 mmol/L to 30 mmol/L and lower detection limit of 0.016 µmol/L (S/N = 3) with remarkable stability and reproducibility of detection BPA under visible light irradiation. Furthermore, the constructed PEC sensor displays favorable potential for detection of BPA in practical applications.
Photothermal therapy (PTT), typically ablates tumors via hyperthermia generated from photothermal agents (PTAs) under laser irradiation, has attracted great attentions in the past decades. Unfortunately, longstanding, frequent and high-power density laser irradiations are needed to maintain the hyperthermal status (> 50 ℃) for efficient therapy, which will damage the skin and nearby healthy tissues. Suppressing cancer cells with a mild temperature elevation is more attractive and feasible for PTT. Recently, low-temperature photothermal therapy (LTPTT), which could inhibit tumor under mild hyperthermia, has been widely investigated by researchers. Herein, we systematically summarized the strategies to achieve LTPTT. Diverse PTAs including organic and inorganic materials reported for LTPTT were introduced. The established strategies for LTPTT were intensively described. Finally, the challenges as well as future perspectives in this field were discussed.
Electrochemical advanced oxidation processes (EAOPs) are effective and environmentally friendly for the treatment of refractory organic pollutants. Among EAOPs, heterogeneous electro-Fenton (EF) process with in-situ formation of hydrogen peroxide (H2O2) is an eco-friendly, cost-effective and easy-operable technology to generate hydroxyl radicals (·OH) with high redox potential. The generation of ·OH is determined by the synergistic H2O2 formation and activation. The surface catalytic mechanisms for H2O2 activation in the heterogeneous EF process were discussed. Some required features such as heteroatom doping and oxygen groups for H2O2 formation via selective two-electron oxygen reduction reaction (ORR) with carbonaceous electrode are summarized. The solid Fenton catalysts and integrated functional cathodes that widely used in heterogeneous EF for wastewater treatment are grouped into few classes. And the brief discussion on catalytic activity and stability of materials over different experimental conditions are given. In addition, the application of heterogeneous EF process on the remediation of emerging contaminants is provided. The challenges and future prospects of the heterogeneous EF processes about catalytic fall-off and multi-step/complex techniques for water purification are emphasized.
Transition metal oxides (TMO) bring a novel direction for the development of energy store materials due to their excellent stability. They not only have high capacity and good cycle performance, but also are cheap and easily available. Zinc oxide (ZnO) as an important part of TMO have gradually attracted attention in the research of electrochemistry. ZnO, as a metal semiconductor with the advantages of wide band gap, possesses high ion migration rate, good chemical stability, simple preparation and low cost, and is widely used in various fields. However, poor conductivity, low permittivity and quick capacity decays quickly impede the commercial application of these electrodes. In recent years, in order to improve the structural stability, ion diffusion and conductivity of zinc oxides-based anodes, various strategies have been raised, such as structural design, surface modification and composition control. In this paper, the recent advances of zinc oxides-based materials for batteries and hybrid supercapacitors (SCs) were introduced. We comprehensively reviewed the prepared process, reaction mechanism and electrochemical performance and discussed the shortcoming of zinc oxides-based nanomaterials. In particular, several insights toward the future research development, practical applications and commercialization of energy storage devices are also proposed for improving the performance of zinc oxides-based materials.
A bioinspired acid-triggered hemiacetalization/dehydration/[3 + 3]-type cycloaddition cascade process was disclosed, diastereoselectively furnishing furo[2,3-b]chromene skeleton under mild conditions. The viability of this approach was demonstrated by syntheses of a series of furo[2,3-b]chromene and pyrano[2,3-b]chromene derivatives. The successful total syntheses of two lignan-phloroglucinol hybrids, hyperaspidinols A and B, exemplified the synthetic utility of our biomimetic methodology.
In this review, the methodologies for fluorine incorporation of 40 fluorine-containing agrochemicals that received an international standardization organization (ISO) name during the last decade are described. The predominant approach for fluorine introduction of these agrochemicals is to use a fluorine-containing building block. Here we present how the fluorine-containing building blocks are introduced into these agrochemicals. The synthetic methods of fluorine-containing building blocks that are not easily available are also specifically discussed. Fluoroarenes, difluomethylarenes and trifluomethylarenes are the main building blocks that have been used in this review. Fluorine-containing small molecules, such as alcohol, amine, ketoester, olefin are also widely used. The only example of late-stage fluorination is the synthesis of fungicide quinofumelin. We believe the fluorine introduction methods described here can provide ideas for the development of new and economical pesticide synthetic routes, and stimulate researchers to develop new fluorine incorporation methods and create new pesticides.
Acenapththylene-imide (AnI), similar to naphthalene diimide (NDI), is an outstanding building block for organic functional materials and has gained a lot of research attention. Herein, Sulphur and Selenium-embedded AnI-containing polycyclic aromatic hydrocarbon molecules, AnI-SQ and AnI-SeQ, with [1, 2, 5]thiadiazolo [3, 4-g]quinoxaline (SQ) and [1, 2, 5]selenadiazolo [3, 4-g]quinoxaline (SeQ) are designed and synthesized with low-lying LUMO energy levels. The absorption and emission of AnI-SQ and AnI-SeQ displayed a bathochromic shift upon protonation of the C = N bond. Besides, theoretical calculation indicates remarkable rigid planar backbones for both AnI-SQ and AnI-SeQ. Through self-assembly with polymeric Pluronic® F-127, corresponding hydrophilic nanoparticles (NPs) were prepared with low cytotoxicity. And AnI-SQ NPs could be applied for in vitro two-photon fluorescence imaging.
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