Latest ArticlesSemiconductor electrocatalysis with weak conductivity can accumulate extremely high carriers at semiconductor-electrolyte interface by self-gating effect, which strongly promotes electrocatalytic efficiency. The correlation between semiconductor carrier mobility and electrocatalysis performance is still unclear. Herein atomic-thin transition metal dichalcogenides based composites have been developed for hydrogen evolution reaction (HER) performed with on-chip microdevices. Electrical and electrochemical measurement of individual flack verified the key role of high carrier mobility for enhanced HER activity. Carrier mobility regulation further demonstrated its high dependence with HER performance under self-gating. Our study provides new insight into the carrier mobility of the semiconductor in the electrocatalysis, paving the way for designing high-performance semiconductor catalysts.
Iron chalcogenides have attracted great interest as potential substitutes of nature enzymes in the colorimetric biological sensing due to their unique chemodynamic characteristics. Herein, we report the preparation of ultrathin FeS nanosheets (NSs) by a simple one-pot hydrothermal method and the prepared FeS NSs exhibit strong Fenton-reaction activity to catalyze hydrogen peroxide (H2O2) for generation of hydroxyl radical (•OH). Based on the chromogenic reaction of resultant •OH with 3, 3′, 5, 5′-tetramethylbenzidine (TMB), we develop colorimetric biosensors for highly sensitive detection of H2O2 and glutathione (GSH). The fabricated biosensors show wide linear ranges for the detection of H2O2 (5–150 µmol/L) and GSH (5–50 µmol/L). Their detection limits for H2O2 and GSH reach as low as 0.19 µmol/L and 0.14 µmol/L, respectively. The experimental results of sensing intracellular H2O2 and GSH demonstrate that this colorimetric method can realize the accurate detection of H2O2 and GSH in normal cells (L02 and 3T3) and cancer cells (MCF-7 and HeLa). Our results have demonstrated that the synthesized FeS NSs is a promising material to construct colorimetric biosensors for the sensitive detection of H2O2 and GSH, holding great promising for medical diagnosis in cancer therapy.
Tailor-made advanced electrocatalysts with high active and stable for hydrogen evolution reaction (HER) play a key role in the development of hydrogen economy. Herein, a N, P-co-doped molybdenum carbide confined in porous carbon matrix (N, P-Mo2C/NPC) with a hierarchical structure is prepared by a resources recovery process. The N, P-Mo2C/NPC compound exhibits outstanding HER activity with a low overpotential of 84 mV to achieve 10 mA/cm2, and excellent stability in alkaline media. The electrochemical measurements confirm that the enhanced HER activity of N, P-Mo2C/NPC is ascribe to the synergy of N, P-codoped and porous carbon matrix. Density functional theory calculations further reveal that the electron density of active sites on Mo2C can be regulated by the N/P doping, leading to optimal H adsorption strength. In this work, the proof-of-concept resource utilization, a microorganism derived molybdenum carbide electrocatalyst for HER is fabricated, which may inaugurate a new way for designing electrocatalysts by the utilization of solid waste.
Bismuth sulfide (Bi2S3) is a promising anode material for high-performance potassium ion batteries due to its high theoretical capacity. However, the poor conductivity and substantial volume expansion hinder its practical application. We proposed an iodine-doped graphene encapsulated Bi2S3 nanorods composite (Bi2S3/IG) as an efficient anode for PIBs. The uniform-sized Bi2S3 nanorods evenly in-situ encapsulated in iodine-doped graphene framework, facilitating the electron transportation and structural stability. The potassium storage performance was evaluated in three electrolytes, with the best option of 5 mol/L KFSI in DME. The reversible capacity of representative Bi2S3/IG reached 453.5 mAh/g at 50 mA/g. Meanwhile, it could deliver an initial reversible capacity of 413.6 mAh/g at 100 mA/g, which maintained 256.9 mAh/g after 200 cycles. The proposed strategy contributes to improving potassium storage performance of metal sulfide anodes.
The specific crystalline form of a compound remarkably affects its physicochemical properties. Therefore, a detailed analysis of the structural features and intermolecular interactions of a multi-component crystal is feasible to understand the relationships among the structure, physicochemical properties and the formation mechanism. In the present study, three novel cocrystal salt solvates of rhein and berberine were reported for the first time. Various solid characterizations and theoretical computations based on density functional theory (DFT) were carried out to demonstrate the intermolecular interactions. The theoretical computation shows that the strongest interaction existed between berberine cation and rhein anion, and the electrostatic interaction play a dominant role. However, no salt bond was observed between them. Further intrinsic dissolution rate analysis in water shows that the monohydrate exhibits 17 times enhancement in comparison with rhein. The rhein and berberine combined in ionic state in cocrystal salt is the main reason for the solubility improvement. This paper suggests that the interactions between the different components can be visualized and qualitatively and quantitatively analyzed by theoretical computation, which is helpful to understand the relationship between stereochemical structure and physicochemical properties of multi-component complex.
Coordination polymers (CPs) have great potential to be used in electrocatalysis owing to their designable compositions and structures. It is highly challenging to apply CPs as electrocatalysts for oxygen evolution reaction (OER) on account of insufficient catalytic efficiency and relatively poor stability of current electrocatalysts. Herein, through a mixed-metal strategy, one-dimensional CoNi1--HIPA with dual active sites was synthesized and studied for OER electrocatalysts. By changing the metal ratio of CoNi1--HIPA, the OER performance was well regulated. The optimized Co1/2Ni1/2-HIPA exhibited minimum reaction activation energy, and represented an overpotential of 367 mV to reach 10 mA/cm2 at 25 ℃. Moreover, an overpotential of 314 mV at 10 mA/cm2 was obtained from Co1/2Ni1/2-HIPA at 55 ℃. This mixed-metal strategy provides a feasible way for adjusting the electronic states of the electrocatalysts to improve the electrocatalytic OER performance.
Cystic echinococcosis (CE) is one of the most harmful and life-threatening helminths. As the essential therapeutics, chemotherapy is always difficult to achieve desired anti-echinococcal effect due to the problems that the echinococcus granulosus cyst laminated layer makes the drug difficult to infiltrate and the poor solubility of drugs. In this study, we established a "breaking-then-curing" anti-echinococcal treatment strategy for efficient CE therapy. The photodynamic therapy (PDT) was used as a breaker to produce toxic reactive oxygen species (ROS) and damage the laminated layer of protoscolices (PSCs), leading to enhanced infiltration of albendazole sulfoxide nanoparticles (ABZSO NPs). Then, ABZSO NP was worked as curer for efficient anti-echinococcal treatment. As a result, the breaking-then-curing treatment strategy could generate more intracellular ROS in PSCs induced by plenty of ABZSO NPs, greatly increasing the mortality rate of PSCs in a shorter time than using ABZSO NPs alone, leading to the attenuation of laminated layer and finally disintegrating PSCs. We believe the "breaking-then-curing" strategy will suggest great potential in the treatment of CE and provide a new sight for anti-echinococcal treatment.
Pathogenic bacteria pose a global threat to public health and attract considerable attention in terms of food safety. Rapid and highly sensitive strategies for detecting pathogenic bacteria must be urgently developed to ensure food safety and public health. Microchips offer significant advantages for pathogenic bacterial detection in terms of speed and sensitivity compared with those of traditional techniques. Microfluidic devices, in particular, have attracted significant attention for the detection of pathogenic bacteria owing to their ease of operation, high throughput, cost-effectiveness, and high sensitivity. This review summarizes representative articles on the analysis of pathogenic bacteria using microchip-based systems. A detailed and comprehensive overview of microchip-based techniques for the detection of pathogenic bacteria is presented herein, and their advantages and disadvantages are discussed to compare their applications. The accomplishments and shortcomings of these microchips have been highlighted, and the direction of development and prospects of the analysis of pathogenic bacteria have been examined. The content of this review is anticipated to provide constructive suggestions for further development of highly effective and advanced microchip-based strategies for detecting pathogenic bacteria.
The works on the procedure of fluorescent sensors for the detection of biological analytes are extremely momentous. Among diverse analytical approaches, fluorescence is the most eye-catching due to its high sensitivity, selectivity, rapidity, robustness, ease of measurement and non-destructive approaches. Herein, we show different fluorescent probes synthesized for estimation and detection of biological analytes (H2S, SO32−/HSO3−, H2O2, HOCl, HNO, ONOO−). These probes were constructed by masking the functional groups (hydroxyl and amino) of fluorophore and formation of active C=C, C=N, C=O and N=N for specific analytes. In this review we concentrate on synthesis of the probe, their photophysical properties and applications to biological studies.
No. 86 Xueyuan South Road, Haidian District, Beijing
010-62199257
qkjq@cast.org.cn
Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House
