Cancer Biology & Medicine

Cancer Biology & Medicine ›› 2026, Vol. 23 ›› Issue (2) : 247 - 251. DOI: 10.20892/j.issn.2095-3941.2025.0585

Letter

Identification of immune reconstitution and hematopoiesis restoration by scRNA-seq in bone marrow of multiple myeloma patients treated with high-dose melphalan following auto-HSCT

Qian Li ¹^,² ,
Yaling Wang ³ ,
Hongfeng Yuan ³ ,
Qiaomei Cai ³ ,
Lina Zhao ²^,³ ,
Li Lin ² ,
Shuang Gao ² ,
Lin Chen ² ,
Zhiying Zhang ² ,
Jing Ma ² ,
Su Liu ² ,
Zeng Cao ¹ ,
Haifeng Zhao ¹ ,
Yufei Wang ³ ,
Shihui Li ³ ,
Pan Lv ³ ,
Huihui Zhang ³ ,
Guowen Wang ⁴ ,
Guang Yang ³ ,
Xiaodong Zhang ³ ,
Yafei Wang ¹^,²

Author information +

¹Department of Hematology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China

²Department of Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, Tianjin 300308, China

³State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine, Tianjin Key Laboratory of Digestive Cancer, Department of Gastrointestinal Cancer Biology, Tianjin Cancer Institute, Liver Cancer Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China

⁴National Key Laboratory of Druggability Evaluation and Systematic Translational Medicine, Tianjin’s Clinical Research Center for Cancer, Department of Bone and Soft Tissue Tumors, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin 300060, China

Correspondence to: Guowen Wang, Guang Yang, Xiaodong Zhang and Yafei Wang, E-mail: wangguowen@tmu.edu.cn, yangguang@tjmuch.com, zhangxiaodong@tjmuch.com and yfwang@tmu.edu.cn

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Received	Accepted	Published
2025-11-10	2026-01-08
Issue Date
2026-11-07

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