The pipeline steel is mainly used for transportation of oil and natural gas as well as the acid service condition means that there are such acidic mediums as H₂S,CO₂ and H⁺ in application environment, so pipeline steel in acid service condition is the pipeline steel with resistance to hydrogen induced corrosion cracking. In the paper, the development and industrial production of X46MS hot rolled coil are mainly introduced. The development includes chemical components, hot rolling process and production technology process as well as the performance tests include pulling, bending, impact, hardness, metallography, non-metallic inclusions and hydrogen induced cracking (HIC). The test results showed that the chemical components and process design of X46MS hot rolled coil in acid service condition were reasonable as well as it was with pure steel, well-closed formation and excellent mechanical properties, especially the resistance to hydrogen induced cracking.