Article(id=1317114986804130685, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1317114959243362461, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260211, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1746633600000, receivedDateStr=2025-05-08, revisedDate=1775491200000, revisedDateStr=2026-04-07, acceptedDate=null, acceptedDateStr=null, onlineDate=1791954283666, onlineDateStr=2026-10-14, pubDate=1792425600000, pubDateStr=2026-10-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791954283666, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791954283666, creator=13701087609, updateTime=1791954283666, updator=13701087609, issue=Issue{id=1317114959243362461, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='10', pageStart='1', pageEnd='137', issueExtLink='null', onlineDate='null', pubDate='1792425600000', pubDateStr='2026-10-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1791954277096, creator='13701087609', updateTime=1792120134547, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317810615909991147, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1317114959243362461, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317810615909991148, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1317114959243362461, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=106, endPage=110, ext={EN=ArticleExt(id=1317114986988680062, articleId=1317114986804130685, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Clinical Study on Traditional Chinese Medicine Therapy Based on the Theory of Miscellaneous Diseases and Hidden Pathogens in the Treatment of Pulmonary Infection in Elderly Patients with Lower Extremity Fractures, columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To study the clinical effect of traditional Chinese medicine therapy based on the theory of miscellaneous diseases and hidden pathogens in the treatment of elderly patients with lower extremity fractures complicated with pulmonary infection.
Methods: 132 elderly patients with lower extremity fractures complicated with pulmonary infection who were admitted to Sichuan Province Orthopedic Hospital from March 2023 to January 2025 were selected and evenly divided into two groups by random single-blind method, including control group (66 cases, conventional western medicine therapy) and trial group (66 cases, traditional Chinese medicine therapy based on the theory of miscellaneous diseases and hidden pathogens in addition to control group). The TCM symptoms scores, clinical pulmonary infection score (CPIS), detection indicators, course of infection and adverse reactions were compared between the two groups.
Results: After treatment, the scores of dimensions of primary syndromes and secondary syndromes in the two groups of patients were decreased (P<0.05), and the scores in trial group were lower than those in control group (P<0.05). After treatment, the scores of dimensions of CPIS were reduced in the two groups of patients (P<0.05), and the reductions in trial group were higher compared to control group (P<0.01). After treatment, the levels of inflammatory factors in both groups of patients were declined (P<0.05), and the levels were lower in trial group than those in control group (P<0.05). The course of infection in trial group was shorter than that in control group (P<0.05). There was no statistical difference in the occurrence of adverse reactions between the two groups (P>0.05).
Conclusion: For elderly patients with lower extremity fractures complicated with pulmonary infection who are differentiated as spleen deficiency and phlegm dampness and blood stasis, the implementation of traditional Chinese medicine therapy based on the theory of miscellaneous diseases and hidden pathogens is helpful to alleviate the symptoms of body discomfort, relieve the degree of pulmonary infection, reduce the levels of inflammatory factors, and shorten the time of antibiotic use, with high safety.
, authors=Jianbiao YUE
1, Qun SUN
1, Linsong LIU
1, Min XUE
2, authorsList=Jianbiao YUE, Qun SUN, Linsong LIU, Min XUE, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317114987244532607, articleId=1317114986804130685, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=基于杂病伏邪理论的中医药治疗老年下肢骨折患者并发肺部感染的临床研究, columnId=1303760933084484510, journalTitle=中医药学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的： 研究基于杂病伏邪理论的中医药治疗老年下肢骨折患者并发肺部感染的临床效果。
方法： 选取四川省骨科医院2023年3月—2025年1月收治的132例老年下肢骨折并发肺部感染的患者，采用随机单盲法将上述患者均分为两组，对照组（66例，采用西医常规治疗）和试验组（66例，对照组基础上添加基于杂病伏邪理论的中医药治疗），比较两组中医证候评分、临床肺部感染评分（CPIS）、检验指标、感染病程及不良反应发生情况。
结果： 治疗后，两组患者主症、次症各维度评分均下降（P<0.05），且试验组均低于对照组（P<0.05）；治疗后，两组患者CPIS各维度评分均下降（P<0.05），且试验组降幅高于对照组（P<0.05）；治疗后，两组患者炎性因子水平均下降（P<0.05），且试验组均低于对照组（P<0.05）；试验组感染病程短于对照组（P<0.05）；两组不良反应相比，差异无统计学意义（P>0.05）。
结论： 对辨证为脾虚痰湿兼瘀阻的老年下肢骨折合并肺部感染患者，实施基于杂病伏邪理论的中医药治疗，有助于缓解机体不适症状，减轻肺部感染程度，降低炎症因子水平，缩短抗生素使用时间，且安全性高。
, authors=岳建彪
1, 孙群
1, 刘林松
1, 薛敏
2, authorsList=岳建彪, 孙群, 刘林松, 薛敏, authorCompany=null, correspAuthors=null, authorNote=
岳建彪（1981-），男，硕士，副主任医师，主要从事内科相关研究。
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岳建彪（1981-），男，硕士，副主任医师，主要从事内科相关研究。
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volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[1], rfOrder=0, authorNames=null, journalName=null, refType=null, unstructuredReference=王孝生, 秦春跃, 刘杨俊. 七叶皂苷钠改善老年下肢骨折术后肿胀疗效及对氧化应激、炎症因子的影响[J]. 分子诊断与治疗杂志, 2025, 17(3): 466-469., articleTitle=null, refAbstract=null), Reference(id=1317504397085618279, tenantId=1146029695717560320, journalId=1302318977290174537, articleId=1317114986804130685, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[2], rfOrder=1, authorNames=null, journalName=null, refType=null, unstructuredReference=毕路甲, 朱建业, 陈辉. 麻醉方式对老年下肢骨折患者术后肺部感染的影响及TLR4/NF-κB信号通路的预测价值[J]. 中华医院感染学杂志, 2024, 34(17): 2646-2650., articleTitle=null, refAbstract=null), Reference(id=1317504397165310056, tenantId=1146029695717560320, journalId=1302318977290174537, articleId=1317114986804130685, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, 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