中医药学报

加减当归补血汤对乳腺癌术后化疗患者气血两虚证的临床疗效观察

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邵大畏 , 毛玲娟

中医药学报 | 临床研究 2026,54(10): 101-105

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中医药学报 |临床研究 2026 , 54 (10) : 101 -105

加减当归补血汤对乳腺癌术后化疗患者气血两虚证的临床疗效观察

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邵大畏, 毛玲娟

作者信息

南京中医药大学武进附属医院乳腺外科，江苏　常州　213161

作者简介:

邵大畏（1986-），男，硕士，主治中医师，主要从事乳腺外科相关研究。

Observation on the Clinical Efficacy of Modified Danggui Buxue Decoction in Patients with Qi and Blood Deficiency Syndrome after Chemotherapy for Breast Cancer

Dawei SHAO, Lingjuan MAO

Affiliations

Department of Breast Surgery, Wujin Affiliated Hospital of Nanjing University of Chinese Medicine, Changzhou 213161, China

出版时间: 2026-10-20 doi: 10.19664/j.cnki.1002-2392.260210

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摘要

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目的：

分析加减当归补血汤对乳腺癌术后化疗患者气血两虚证的临床疗效。

方法：

选取南京中医药大学武进附属医院2023年2月—2025年1月收治的98例气血两虚证乳腺癌术后化疗患者，随机数字表法分为对照组和观察组，每组49例，对照组予以常规治疗，观察组加用加减当归补血汤，比较两组临床疗效、中医证候积分、免疫功能、生活质量，观察两组发生不良反应情况。

结果：

观察组疾病控制率（DCR）高于对照组（P<0.05）。治疗后，观察组CD3⁺、CD4⁺、CD4⁺/CD8⁺水平、生活质量评分高于对照组（P<0.01），CD8⁺水平、中医证候各项积分低于对照组（P<0.01）。两组不良反应发生率比较，差异无统计学意义（P>0.05）。对患者随访6个月，观察组复发率4.08%（2/49）低于对照组16.33%（8/49）（χ²值=4.009，P=0.045）。

结论：

乳腺癌术后化疗患者采取加减当归补血汤治疗效果显著，可减轻中医证候积分，改善免疫功能，提升患者生活质量，复发率较低。

关键词

加减当归补血汤 / 乳腺癌 / 化疗 / 气血两虚证

Abstract

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Objective:

To analyze the clinical efficacy of modified Danggui Buxue Decoction on patients with qi and blood deficiency syndrome after postoperative chemotherapy for breast cancer.

Methods:

A total of 98 breast cancer patients with qi and blood deficiency syndrome who underwent postoperative chemotherapy and were admitted to our hospital from February 2023 to January 2025 were randomly divided into two groups by random number table method. The control group was given conventional treatment, while the observation group was additionally treated with modified Danggui Buxue Decoction. The therapeutic effects of the two groups were compared.

Result:

The disease control rate (DCR) of the observation group was higher than that of the control group (P<0.05). After treatment, the levels of CD3⁺, CD4⁺, CD4⁺/CD8⁺ and the quality of life score in the observation group were higher than those in the control group, while the level of CD8⁺ and the scores of each item of traditional Chinese medicine syndrome were lower than those in the control group (P<0.01). Comparison of the incidence of adverse reactions between groups (P>0.05). The patients were followed up for 6 months. The recurrence rate of the observation group was 4.08% (2/49), which was lower than that of the control group at 16.33% (8/49) (χ² value 4.009, P value=0.045).

Conclusion:

The modified Danggui Buxue Decoction has a significant therapeutic effect on patients undergoing chemotherapy after breast cancer surgery. It can reduce the TCM syndrome score, improve immune function, enhance the quality of life of patients, and has a relatively low recurrence rate.

Key words

Modified Danggui Buxue Decoction / Breast cancer / Chemotherapy / Qi and blood deficiency syndrome

引用本文

邵大畏, 毛玲娟. 加减当归补血汤对乳腺癌术后化疗患者气血两虚证的临床疗效观察. 中医药学报, 2026 , 54 (10) : 101 -105 . DOI: 10.19664/j.cnki.1002-2392.260210

Dawei SHAO, Lingjuan MAO. Observation on the Clinical Efficacy of Modified Danggui Buxue Decoction in Patients with Qi and Blood Deficiency Syndrome after Chemotherapy for Breast Cancer[J]. Acta Chinese Medicine and Pharmacology, 2026 , 54 (10) : 101 -105 . DOI: 10.19664/j.cnki.1002-2392.260210

基金

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江苏省自然科学基金项目(BK20221424)

参考文献

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2026年第54卷第10期

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doi: 10.19664/j.cnki.1002-2392.260210

接收时间：2025-09-10
首发时间：2026-10-14
出版时间：2026-10-20

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收稿日期：2025-09-10
修回日期：2026-05-26

基金

江苏省自然科学基金项目(BK20221424)

作者信息

南京中医药大学武进附属医院乳腺外科，江苏　常州　213161

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2种不同金属材料的力学参数

科 Family	属数 Number of genus	种数 Number of species	占总种数比例 Percentage of total species (%)	属 Genus	种数 Number of species	占总种数比例 Percentage of total species (%)
鹅膏菌科Amanitaceae	2	11	5.26	鹅膏菌属 Amanita	10	4.78
小菇科 Mycenaceae	2	12	5.74	丝盖伞属 Inocybe	5	2.39
多孔菌科 Polyporaceae	8	14	6.70	蜡蘑属 Laccaria	5	2.39
红菇科 Russulaceae	3	23	11.00	小皮伞属 Marasmius	6	2.87
				小菇属 Mycena	11	5.26
				光柄菇属 Pluteus	5	2.39
				红菇属 Russula	17	8.13
				栓菌属 Trametes	5	2.39

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