Article(id=1307269630855242413, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1307269601637724372, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260103, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1731513600000, receivedDateStr=2024-11-14, revisedDate=1756224000000, revisedDateStr=2025-08-27, acceptedDate=null, acceptedDateStr=null, onlineDate=1789606967891, onlineDateStr=2026-09-17, pubDate=1779206400000, pubDateStr=2026-05-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789606967891, onlineIssueDateStr=2026-09-17, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789606967891, creator=13701087609, updateTime=1789606967891, updator=13701087609, issue=Issue{id=1307269601637724372, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='5', pageStart='1', pageEnd='126', issueExtLink='null', onlineDate='null', pubDate='1779206400000', pubDateStr='2026-05-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1789606960925, creator='13701087609', updateTime=1789606960925, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=87, endPage=92, ext={EN=ArticleExt(id=1307269631002043054, articleId=1307269630855242413, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Effects of Electroacupuncture Combined with Traditional Chinese Medicinal Fumigation on Skin Barrier Function in Moderate-to-Severe Atopic Dermatitis Patients with Blood Deficiency and Wind Dryness Pattern, columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To explore the effect of electroacupuncture combined with traditional Chinese medicine fumigation on skin barrier function in patients with moderate to severe atopic dermatitis (AD) of blood deficiency and wind dryness type.
Method: Selected from April 2020 to October 2024, The case data of 96 AD patients admitted to the acupuncture and moxibustion and Massage Department of the First Affiliated Hospital of Xinjiang Medical University were selected, they were randomly divided into two groups, with 48 cases in each group. The control group received Western medicine treatment, while the observation group received electroacupuncture combined with traditional Chinese medicine fumigation treatment. The SCORAD score, skin barrier function indicators, immune function treatment before and after treatment were compared between the two groups, and the clinical efficacy and recurrence rate after 6 months of follow-up and adverse reaction incidence rate were also compared.
Result: After treatment, the water content, sebum content, and interleukin-2 (IL-2) in the stratum corneum of both groups were significantly increased compared to before treatment (P < 0.05). SCORAD scores, transcutaneous water loss (TEWL), eosinophils (EOS), serum immunoglobulin E (IgE), and interleukin-4 (IL-4) were significantly reduced compared to before treatment (P <0.05), and the improvement was more significant in the observation group (P < 0.05). In terms of treatment efficiency, 97.92% in the observation group was significantly better than 81.25% in the control group (P < 0.05) ; The therapeutic effect efficiency was better in the observation group at 97.92% compared to the control group at 81.25% (P <0.05) ; The recurrence rate after 6 months of follow-up was significantly lower in the observation group at 16.67% compared to the control group at 56.25% (P <0.05) ;The incidence of adverse reactions in the observation group (4.17%) was lower than that in the control group (16.67%) (P < 0.05).
Conclusion: The combination of electroacupuncture combined with traditional Chinese medicinal fumigation for treating moderate to severe AD patients with blood deficiency and wind dryness is more effective than using Western medicine alone. It can effectively alleviate symptoms, improve skin barriers, regulate immune function, and prevent recurrence.
, authors=Qin JI, Xianglai NIU
*, authorsList=Qin JI, Xianglai NIU, authorCompany=null, correspAuthors=Xianglai NIU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1307269631782183599, articleId=1307269630855242413, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=电针联合中药塌渍对血虚风燥型中重度特应性皮炎皮肤屏障功能的影响, columnId=1303760933084484510, journalTitle=中医药学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的： 探讨电针联合中药塌渍对血虚风燥型中重度特应性皮炎（AD）患者皮肤屏障功能的影响。
方法： 选取2020年4月—2024年10月新疆医科大学第一附属医院中医诊疗中心针灸推拿科收治的96例AD患者病例资料，随机分为对照组和观察组，每组48例，对照组采用西医治疗，观察组在此基础上加用电针联合中药塌渍治疗，比较两组治疗前后特应性皮炎积分（SCORAD）评分、皮肤屏障功能指标、免疫功能治疗，并比较治疗后临床疗效及随访6个月复发率、不良反应发生率。
结果： 治疗后，两组角质层含水量、皮脂含量、白细胞介素-2（IL-2）比治疗前明显提升（P < 0.05），SCORAD各项评分、经皮水分丢失量（TEWL）、嗜酸性粒细胞（EOS）、血清免疫球蛋白E（IgE）、白细胞介素-4（IL-4）比治疗前明显下降（P < 0.05），观察组改善幅度更明显（P < 0.05）。观察组的总有效率为97.92% （47/48），对照组总有效率为81.25% （39/48），观察组明显高于对照组（P < 0.01）；随访 6个月，观察组的复发率为16.67%（8/48），对照组复发率为56.25% （27/48），观察组明显低于对照组（P < 0.01）；观察组不良反应发生率为4.17% （2/48），低于对照组的16.67% （8/48），差异有统计学意义（P < 0.05）。
结论： 血虚风燥型中重度AD患者采用电针联合中药塌渍的治疗效果明显，优于单用西医治疗，能有效缓解症状，改善皮肤屏障和调节免疫功能，预防复发。
, authors=吉勤, 牛相来
*, authorsList=吉勤, 牛相来, authorCompany=null, correspAuthors=牛相来, authorNote=
吉勤（1992-），女，硕士，住院医师，研究方向：针灸治疗皮肤病。
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* 牛相来（1972-），男，硕士，副主任医师，研究方向：针灸治疗皮肤病。
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