Article(id=1307269495731540042, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1307269479684133809, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260144, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1733155200000, receivedDateStr=2024-12-03, revisedDate=1764604800000, revisedDateStr=2025-12-02, acceptedDate=null, acceptedDateStr=null, onlineDate=1789606935674, onlineDateStr=2026-09-17, pubDate=1784476800000, pubDateStr=2026-07-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789606935674, onlineIssueDateStr=2026-09-17, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789606935674, creator=13701087609, updateTime=1789606935674, updator=13701087609, issue=Issue{id=1307269479684133809, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='7', pageStart='1', pageEnd='128', issueExtLink='null', onlineDate='null', pubDate='1784476800000', pubDateStr='2026-07-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1789606931849, creator='13701087609', updateTime=1789606931849, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=72, endPage=76, ext={EN=ArticleExt(id=1307269495920283723, articleId=1307269495731540042, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Clinical Efficacy of Modified Tongbi Formula Combined with Traditional Chinese Medicine Fumigation in the Treatment of Rheumatoid Arthritis with Cold-Dampness Obstruction Pattern, columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To analyze the effect of Modified Tongbi Formula combined with traditional Chinese medicine fumigation on rheumatoid arthritis (RA) syndrome of cold-dampness obstruction.
Methods: 168 patients with RA cold-dampness obstruction syndrome admitted to the Eastern Theater General Hospital from April 2021 to June 2024 were divided into 2 groups according to different treatment methods. 83 patients in the control group were treated with traditional Chinese medicine fumigation, and 85 patients in the observation group were treated with Modified Tongbi Formula. The therapeutic effect of the two groups was compared.
Results: The treatment effect of observation group was compared with control group (P <0.05). After treatment, TCM syndrome score, 28 joint activity score (DAS28) and clinical disease activity index (CDAI) in observation group were lower than those in control group (P < 0.05). After treatment, the levels of rheumatoid factor (RF), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), D-dimer (D-D) and immunoglobulin (IgG, IgA, IgM) in observation group were lower than those in control group (P < 0.05). The incidence of adverse reactions was compared between observation group and control group (P >0.05).
Conclusion: Modified Tongbi Formula combined with traditional Chinese medicine fumigation has a remarkable effect, which can significantly reduce the score of traditional Chinese medicine symptoms, significantly reduce the level of inflammation, enhance immune function, reduce disease activity, and do not increase adverse drug reactions.
, authors=Bingjie LIU, Qian WANG, Ying WANG, Zhiyan HAN, Xue YANG
*, authorsList=Bingjie LIU, Qian WANG, Ying WANG, Zhiyan HAN, Xue YANG, authorCompany=null, correspAuthors=Xue YANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1307269496482320460, articleId=1307269495731540042, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=加减通痹方联合中药熏蒸治疗寒湿痹阻型类风湿关节炎临床疗效, columnId=1303760933084484510, journalTitle=中医药学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的： 分析加减通痹方联合中药熏蒸治疗寒湿痹阻型类风湿关节炎（RA）的治疗效果。
方法： 选取2021年4月—2024年6月东部战区总医院收治的168例RA寒湿痹阻证患者，按照不同治疗方法分为对照组和观察组，对照组83例采取中药熏蒸治疗，观察组85例加用加减通痹方治疗，比较两组治疗效果，比较两组疾病活动性指标、血清及免疫指标，并观察两组的不良反应发生情况。
结果： 观察组治疗效果优于对照组（P < 0.05）。治疗后，观察组中医证候积分、28处关节活动性评分（DAS28）、临床疾病活动指数（CDAI）较对照组更低（P < 0.01）。治疗后，观察组类风湿因子（RF）、C反应蛋白（CRP）、红细胞沉降率（ESR）、D-二聚体（D-D）水平、免疫球蛋白（IgG、IgA、IgM）低于对照组（P < 0.01）。观察组与对照组不良反应发生率比较，差异无统计学意义（P > 0.05）。
结论： 采取加减通痹方联合中药熏蒸治疗寒湿痹阻型类风湿关节炎效果显著，可明显降低中医证候积分，减轻炎症水平，提升免疫功能，降低疾病活动度，无特殊药物不良反应。
, authors=刘冰洁, 王倩, 王颖, 韩知言, 杨雪
*, authorsList=刘冰洁, 王倩, 王颖, 韩知言, 杨雪, authorCompany=null, correspAuthors=杨雪, authorNote=
刘冰洁（1993-），女，硕士，住院医师，从事中医内科学、保健医学及全科医学相关研究。
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* 杨雪（1995 -），女，硕士，住院医师，从事中医内科学、保健医学及全科医学相关研究。
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刘冰洁（1993-），女，硕士，住院医师，从事中医内科学、保健医学及全科医学相关研究。
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刘冰洁（1993-），女，硕士，住院医师，从事中医内科学、保健医学及全科医学相关研究。
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