Article(id=1307269495593132920, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1307269479684133809, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260141, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1720713600000, receivedDateStr=2024-07-12, revisedDate=1743004800000, revisedDateStr=2025-03-27, acceptedDate=null, acceptedDateStr=null, onlineDate=1789606935642, onlineDateStr=2026-09-17, pubDate=1784476800000, pubDateStr=2026-07-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789606935642, onlineIssueDateStr=2026-09-17, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789606935642, creator=13701087609, updateTime=1789606935642, updator=13701087609, issue=Issue{id=1307269479684133809, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='7', pageStart='1', pageEnd='128', issueExtLink='null', onlineDate='null', pubDate='1784476800000', pubDateStr='2026-07-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1789606931849, creator='13701087609', updateTime=1789606931849, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=56, endPage=60, ext={EN=ArticleExt(id=1307269495756710777, articleId=1307269495593132920, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Retrospective Analysis of the Efficacy of Xiegan Zhitong Decoction Combined with Western Medicine in Treating Herpes Zoster with Liver Channel Stagnation-Heat Syndrome, columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To investigate the efficacy and safety of Xiegan Zhitong Decoction combined with famciclovir tablets and mecobalamin tablets in treating herpes zoster with liver channel stagnation-heat syndrome.
Methods: 92 patients diagnosed with herpes zoster with liver channel stagnation-heat syndrome in the Department of Dermatology of Third Affiliated Hospital of Beijing University of Chinese Medicine from June 2022 to June 2024 were included. All patients received oral Xiegan Zhitong Decoction (1 dose/day, decocted in water) for one week as one treatment course, combined with famciclovir tablets for antiviral treatment and mecobalamin tablets for nerve nutrition. Clinical efficacy at different treatment courses, time-effect scores (time to stop blistering, crust formation time, crust shedding time, and pain relief time), pain and sleep scores, incidence of postherpetic neuralgia, and TCM syndrome scores were evaluated.
Results: After treatment at each course, significant improvements were observed in time-effect scores, sleep and pain scores, and TCM syndrome scores (P <0.01, P < 0.001). The cumulative effective rates at 1, 2, 3, and 4 weeks were 27.17% (25/92), 88.04% (81/92), 94.57% (87/92), and 98.91% (91/92) respectively. The incidence of postherpetic neuralgia was 1.09% (1/92).
Conclusion: Xiegan Zhitong Decoction combined with famciclovir and mecobalamin tablets shows significant efficacy in treating herpes zoster with liver channel stagnation-heat syndrome, shortening recovery time, improving sleep, reducing pain, ameliorating TCM syndromes, with low incidence of postherpetic neuralgia and few adverse reactions.
, authors=Lili ZHANG, Linxian LI, Ziyi FAN, Zhanxue SUN
*, authorsList=Lili ZHANG, Linxian LI, Ziyi FAN, Zhanxue SUN, authorCompany=null, correspAuthors=Zhanxue SUN, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1307269496130003834, articleId=1307269495593132920, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=泻肝止痛汤联合西药治疗肝经郁热型带状疱疹的疗效回顾分析, columnId=1303760933084484510, journalTitle=中医药学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的： 探究泻肝止痛汤结合泛昔洛韦片、甲钴胺片治疗带状疱疹肝经郁热证的效果和安全性。
方法： 纳入北京中医药大学第三附属医院皮肤科2022年6月—2024年6月诊断为带状疱疹肝经郁热证的92例患者，均口服泻肝止痛汤，1剂/d，水煎服，1周为1个疗程，口服泛昔洛韦片抗病毒和甲钴胺片营养神经治疗。评价不同疗程的临床效果、时效评分（止疱时间、结痂时间、脱痂时间、止痛时间）、疼痛、睡眠评分、后遗神经痛发生率及中医证候积分。
结果： 各疗程治疗后，时效评分、睡眠、疼痛评分及中医证候积分均显著改善（P < 0.01，P < 0.001）。疗程1、2、3、4周的累计有效率分别为27.17% （25/92）、88.04% （81/92）、94.57% （87/92）、98.91% （91/92），后遗神经痛的发生率为1.09% （1/92）。
结论： 泻肝止痛汤联合泛昔洛韦片、甲钴胺片治疗带状疱疹肝经郁热证疗效显著，可缩短恢复时间，改善睡眠，降低疼痛，改善中医证候，后遗神经痛发生率低，不良反应少。
, authors=张莉莉, 李林仙, 范子怡, 孙占学
*, authorsList=张莉莉, 李林仙, 范子怡, 孙占学, authorCompany=null, correspAuthors=孙占学, authorNote=
张莉莉（1992-），女，博士，住院医师，研究方向：中医药治疗变态免疫性皮肤病。
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* 孙占学（1973 -），男，博士，主任医师，博士生导师，研究方向：中医药治疗变态免疫性皮肤病。
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张莉莉（1992-），女，博士，住院医师，研究方向：中医药治疗变态免疫性皮肤病。
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张莉莉（1992-），女，博士，住院医师，研究方向：中医药治疗变态免疫性皮肤病。
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