Article(id=1307269486269195048, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1307269479684133809, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260136, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1725292800000, receivedDateStr=2024-09-03, revisedDate=1771948800000, revisedDateStr=2026-02-25, acceptedDate=null, acceptedDateStr=null, onlineDate=1789606933419, onlineDateStr=2026-09-17, pubDate=1784476800000, pubDateStr=2026-07-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789606933419, onlineIssueDateStr=2026-09-17, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789606933419, creator=13701087609, updateTime=1789606933419, updator=13701087609, issue=Issue{id=1307269479684133809, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='7', pageStart='1', pageEnd='128', issueExtLink='null', onlineDate='null', pubDate='1784476800000', pubDateStr='2026-07-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1789606931849, creator='13701087609', updateTime=1789606931849, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=25, endPage=32, ext={EN=ArticleExt(id=1307269486436967209, articleId=1307269486269195048, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Study on the Extraction Process of Total Flavonoids from Mayaqi and Its Antioxidant Activity and Stability, columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To optimize the extraction process of total flavonoids from Mayaqi and study its antioxidant activity and stability.
Method: Key factors were screened by Plackett-Burman experiment, and the optimal process was obtained by Box-Behnken Design surface design; The antioxidant activity of total flavonoids of Mayaqi was evaluated by measuring the scavenging effects on hydroxyl radicals, DPPH radicals, ABTS radicals and the ability to reduce ferric ions. The correlation between the concentration of total flavonoids extract and different antioxidant activities was by SPSS software, and the effects of temperature, light and pH on the stability of antioxidant activity were investigated.
Result: The optimal extraction technology for total flavonoids from Mayaqi was as follows: extraction 140 W, ethanol concentration 65%, temperature 70 ℃, extraction time 30 min, and the extraction rate of total flavoids was 4.608 5 ±0.031 7 mg/g. The scavenging effects of the total flavonoids extract on Mayaqi DPPH radicals, and ABTS radicals, and the ability to reduce ferric ions were 64.16%、55.67%、95.97% and 50.49%, of the same concentration of Vc, respectively. Correlation showed that the concentration of the total flavonoids extract from Mayaqi was significantly correlated with the scavenging rate of xyl radicals. The antioxidant stability test showed that the total flavonoids extract from Mayaqi should be stored at low (below 25 ℃), away from light, and in neutral conditions.
Conclusion: This technology is stable and feasible, and the total flavonoids extract Mayaqi has high antioxidant activity.
, authors=Jing CHEN
1, Wei WANG
2, Shaoping HOU
3, Junwei XI
1, *, authorsList=Jing CHEN, Wei WANG, Shaoping HOU, Junwei XI, authorCompany=null, correspAuthors=Junwei XI, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1307269486982226730, articleId=1307269486269195048, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=马牙七总黄酮提取工艺及其抗氧化活性
、稳定性研究, columnId=1303760928135213534, journalTitle=中医药学报, columnName=中药研究, runingTitle=null, highlight=null, articleAbstract=
目的： 优化马牙七总黄酮提取工艺并研究其抗氧化活性及其稳定性。
方法： 采用Plackett-Bur-man试验筛选关键因子，再经Box-Behnken Design响应面设计得到最佳工艺；通过测定羟自由基、DPPH自由基、ABTS自由基的清除作用及铁离子还原能力评价马牙七总黄酮的抗氧化活性，经SPSS软件分析马牙七总黄酮提取物浓度和不同抗氧化活性的相关性，并考察温度、光照和pH对抗氧化活性稳定性的影响。
结果： 马牙七总黄酮最佳提取工艺为提取功率140 W，乙醇浓度65%，温度70 ℃，提取时间30 min，马牙七总黄酮得率为（4.608 5 ± 0.031 7） mg/g。马牙七总黄酮提取物对羟自由基、DPPH自由基、ABTS自由基的清除作用及铁离子最大还原能力分别为同浓度Vc的64.16%、55.67%、95.97%和50.49%。相关性分析表明，马牙七总黄酮提取物浓度与羟自由基的清除率相关性最显著。抗氧化稳定性试验表明，马牙七总黄酮提取物应在低温（25 ℃以下）、避光及中性条件下保存。
结论： 该工艺稳定可行，马牙七总黄酮提取物具有很高的抗氧化活性。
, authors=陈静
1, 王维
2, 侯少平
3, 奚军伟
1, *, authorsList=陈静, 王维, 侯少平, 奚军伟, authorCompany=null, correspAuthors=奚军伟, authorNote=
陈静（1983-），女，主管药师，从事药品监管相关工作。
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* 奚军伟（1979 -），男，副主任药师，从事药品监管相关工作。
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