Article(id=1307264631395873341, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1307264617252680149, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260165, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1753027200000, receivedDateStr=2025-07-21, revisedDate=1779379200000, revisedDateStr=2026-05-22, acceptedDate=null, acceptedDateStr=null, onlineDate=1789605775926, onlineDateStr=2026-09-17, pubDate=1787155200000, pubDateStr=2026-08-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789605775926, onlineIssueDateStr=2026-09-17, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789605775926, creator=13701087609, updateTime=1789605775926, updator=13701087609, issue=Issue{id=1307264617252680149, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='8', pageStart='1', pageEnd='128', issueExtLink='null', onlineDate='null', pubDate='1787155200000', pubDateStr='2026-08-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1789605772555, creator='13701087609', updateTime=1789605772555, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=81, endPage=85, ext={EN=ArticleExt(id=1307264633056817726, articleId=1307264631395873341, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Effects of Modified Yulin Zhu Combined with Warming-Needle Moxibustion on Endometrial Receptivity in Patients of Thin Endometrium with Kidney Deficiency and Blood Stasis Type, columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To study the effects of Modified Yulin Zhu combined with warm acupuncture on endometrial receptivity and serum leukemia inhibitory factor (LIF) vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9) levels in patients with thin endometrium of renal deficiency and blood stasis type.
Methods: 84 patients with thin endometrium (renal deficiency and blood stasis type) admitted to Taizhou Hospital of Traditional Chinese Medicine from January 2023 to September 2024 were selected, the grouping method was random number table method, the patients were divided into control group (treated with estradiol tablets/estradiol dydrogesterone tablets composite packaging, 42 cases) and observation group (treated with Modified Yulin Zhu and warm acupuncture on the basis of control group, 42 cases), the clinical efficacy, traditional Chinese medicine syndrome score, menstrual blood volume score, endometrial receptivity, serum LIF, VEGF, MMP-9 and incidence of adverse reactions were compared between two groups.
Results: The total clinical effective rate of the observation group was higher than that of control group (P <0.05). Traditional Chinese medicine syndrome score in observation group were lower than those in control group 3 months after treatment, the endometrial thickness was greater than that in control group, and menstrual blood volume score, serum LIF, MMP-9 and VEGF were higher than those in control group (P <0.01). There was no difference in the incidence of adverse reactions between the observation group and the control group (P > 0.05).
Conclusion: Modified Yulin Zhu combine with warm acupuncture treatment, which can improve the clinical symptoms of patients with thin endometrium of renal deficiency and blood stasis type, and regulate endometrial receptivity, which may be relate to the improvement of serum LIF, VEGF and MMP-9 levels.
, authors=Caiping FANG, Hong ZHU, Sufen GUAN, Yao YAO, Yumei BAO, Yan CHEN
*, authorsList=Caiping FANG, Hong ZHU, Sufen GUAN, Yao YAO, Yumei BAO, Yan CHEN, authorCompany=null, correspAuthors=Yan CHEN, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1307264633417527871, articleId=1307264631395873341, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=毓麟珠加减联合温针灸对肾虚血瘀型薄型子宫内膜患者子宫内膜容受性的影响, columnId=1303760933084484510, journalTitle=中医药学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的： 观察毓麟珠加减联合温针灸对肾虚血瘀型薄型子宫内膜患者子宫内膜容受性及血清白血病抑制因子（LIF）、血管内皮生长因子（VEGF）、基质金属酶蛋白9（MMP-9）水平的影响。
方法： 选取2023年1月—2024年9月泰州市中医院收治的薄型子宫内膜患者（肾虚血瘀型）84例，采用随机数字表法分为对照组（42例，接受雌二醇片/雌二醇地屈孕酮片复合包装治疗）和观察组（42例，对照组的基础上结合毓麟珠加减、温针灸治疗），对比两组临床疗效、中医证候积分、月经血量评分、子宫内膜容受性、血清LIF、VEGF、MMP-9和不良反应发生率。
结果： 观察组临床总有效率高于对照组（P < 0.05）。观察组治疗3个月后中医证候积分低于对照组（P < 0.01），子宫内膜厚度大于对照组（P < 0.01），月经血量评分、血清LIF、MMP-9、VEGF高于对照组（P < 0.01）。观察组和对照组不良反应发生率比较无差异（P > 0.05）。
结论： 毓麟珠加减联合温针灸治疗，可改善肾虚血瘀型薄型子宫内膜患者的临床症状，调节子宫内膜容受性，考虑可能与改善血清LIF、VEGF、MMP-9水平有关。
, authors=房彩平, 朱虹, 管素芬, 姚瑶, 鲍玉梅, 陈琰
*, authorsList=房彩平, 朱虹, 管素芬, 姚瑶, 鲍玉梅, 陈琰, authorCompany=null, correspAuthors=陈琰, authorNote=
房彩平（1985-），女，硕士，副主任中医师，从事中医妇科相关研究。
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* 陈琰（1978-），女，博士，主任中医师，从事中医妇科相关研究。
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