Article(id=1305171221532931005, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1305171206701871960, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260180, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1754323200000, receivedDateStr=2025-08-05, revisedDate=1779033600000, revisedDateStr=2026-05-18, acceptedDate=null, acceptedDateStr=null, onlineDate=1789106668122, onlineDateStr=2026-09-11, pubDate=1789833600000, pubDateStr=2026-09-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789106668122, onlineIssueDateStr=2026-09-11, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789106668122, creator=13701087609, updateTime=1789106668122, updator=13701087609, issue=Issue{id=1305171206701871960, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='9', pageStart='1', pageEnd='133', issueExtLink='null', onlineDate='null', pubDate='1789833600000', pubDateStr='2026-09-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1789106664586, creator='13701087609', updateTime=1789106805687, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1305171798593663109, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1305171206701871960, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1305171798593663110, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1305171206701871960, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=54, endPage=59, ext={EN=ArticleExt(id=1305171221725868990, articleId=1305171221532931005, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Efficacy of Acupuncture Combined with Electroacupuncture for Early-to-Mid-Stage Knee Osteoarthritis Based on the "Shaoyang Governing the Bone" Theory, columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To evaluate the clinical efficacy of acupuncture combined with electroacupuncture in the treatment of early to mid-stage osteoarthritis of the knee based on the theory of 'Shaoyang Governing the Bone'.
Methods: A total of 102 patients with early to mid-stage knee osteoarthritis (KOA) admitted to Sichuan Orthopedic Hospital from August 2022 to August 2024 were enrolled and randomly assigned to the observation group (n = 50) or the control group (n = 52). All patients received basic treatment and specific exercise training. In the control group, early-stage patients were treated with meloxicam tablets and glucosamine hydrochloride capsules, while mid-stage patients additionally received intra-articular sodium hyaluronate injection. On the basis of the control regimen, patients in the observation group underwent acupuncture treatment guided by the "Shaoyang governing bone" theory combined with electroacupuncture using a sparse-dense wave. Both groups were treated for three courses, with each course lasting two weeks. Observe the changes of clinical efficacy, SF-36 health survey scale score, TCM symptom score, WOMAC and VAS scale score, β-collagen degradation product (β-CTX) and 25 hydroxyvitamin D (25-OH-D) level in the two groups.
Results: After three courses of treatment, the total efficacy rate of 98. 00% in the observation group was significantly higher than that of 84.62% in the control group (P <0.05), the scores of the eight dimensions of SF-36 scale were significantly improved (P <0.05), the TCM symptom scores, the scores of WOMAC and VAS scales were significantly reduced (P <0.05), the level of β-CTX was significantly reduced (P <0.05) and 25-OH-VD levels were significantly higher (P <0.05), and the improvement of all indicators was more obvious in the observation group (P < 0.05). In addition, there were 3 cases of adverse reactions in the observation group and 4 cases in the control group, indicating that this study has a better safety profile.
Conclusion: Based on the theory that "Shaoyang governing the bones," the therapeutic approach combining the method of regulating qi, activating blood circulation, and tonifying the kidney with electroacupuncture has shown good clinical efficacy in the treatment of early- and middle-stage knee osteoarthritis. It can significantly improve patients' quality of life, relieve pain, regulate bone metabolism to reduce bone loss, slow down joint degeneration, enhance bone health, and thereby improve knee joint function.
, authors=Liyang WANG, Hu SHA
*, Jing XU, Jia WU, Jinhong ZOU, authorsList=Liyang WANG, Hu SHA, Jing XU, Jia WU, Jinhong ZOU, authorCompany=null, correspAuthors=Hu SHA, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1305171222195631039, articleId=1305171221532931005, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=基于“少阳主骨”理论的调气活血补肾针法联合电针治疗早中期膝骨关节炎的疗效观察, columnId=1303760931671011820, journalTitle=中医药学报, columnName=针灸经络, runingTitle=null, highlight=null, articleAbstract=
目的： 评价基于“少阳主骨”理论探讨调气活血补肾法针法联合电针治疗早中期膝骨关节炎的临床疗效。
方法： 纳入2022年8月—2024年8月四川省骨科医院收治的早中期膝骨关节炎患者102例，随机分为观察组50例、对照组52例，给予所有基础治疗及专项运动锻炼，对照组早期患者服用美洛昔康片与盐酸氨基葡萄糖胶囊，中期患者在早期的基础上，加用玻璃酸钠注射液，观察组患者在对照组的基础上，根据“少阳主骨”理论进行针法治疗，并辅以电针疏密波刺激，两组均以2周为1个疗程，共治疗3个疗程。观察两组患者临床疗效、SF-36健康调查量表评分，中医症状积分、WOMAC与VAS量表评分、β胶原降解产物（β-CTX）与25羟基维生素D（25-OH-D）水平的变化。
结果： 经过3个疗程治疗后，观察组总有效率为98.00% （49/50）明显高于对照组的84.62% （44/52），差异有统计学意义（P <0.05），SF-36量表8个维度评分均明显提升（P < 0.05），中医症状积分、WOMAC与VAS量表评分均明显降低（P < 0.05），β-CTX水平显著降低（P < 0.05），25-OH-VD水平明显升高（P < 0.05），各项指标以观察组改善更为明显（P < 0.05）。两组不良反应发生率比较，差异无统计学意义（P > 0.05）。
结论： 基于“少阳主骨”理论的调气活血补肾法针法联合电针治疗早中期膝骨关节炎的过程中显示出较好的疗效，能够明显提高患者生活质量，减轻患者疼痛，并通过调节骨代谢减少骨质流失、减缓关节退变过程、改善骨骼健康，进而改善膝关节功能。
, authors=王立阳, 沙湖
*, 许静, 吴佳, 邹金宏, authorsList=王立阳, 沙湖, 许静, 吴佳, 邹金宏, authorCompany=null, correspAuthors=沙湖, authorNote=
王立阳（1996-），男，硕士，住院医师，研究方向：风湿骨关节类疾病。
, correspAuthorsNote=
* 沙湖（1984 -），男，硕士，副主任医师，研究方向：风湿及骨关节相关疾病中西医结合治疗及微创手术治疗。
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王立阳（1996-），男，硕士，住院医师，研究方向：风湿骨关节类疾病。
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王立阳（1996-），男，硕士，住院医师，研究方向：风湿骨关节类疾病。
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