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灵芝多糖化学结构及药理作用研究进展
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中医药学报 | 研究进展 2026,54(2): 120-128
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中医药学报 |研究进展 2026 , 54 (2) : 120 -128
灵芝多糖化学结构及药理作用研究进展
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井晓婕1, 姜思亮1, 夏永刚1, 梁军1
作者信息
    1 黑龙江中医药大学教育部北药基础与应用研究重点实验室,黑龙江省中药及天然药物药效物质基础重点实验室,黑龙江 哈尔滨 150040
通讯作者:
* 梁军(1984-),女,博士,研究员,硕士研究生导师,研究方向:中药药效物质基础及质量评价研究。
作者简介:
井晓婕(1998-),女,硕士研究生,研究方向:中药药效物质基础研究。
Research Progress on Chemical Structure and Pharmacological Effects of Ganoderma Polysaccharides
  • JING Xiaojie1, JIANG Siliang1, XIA Yonggang1, LIANG Jun1
  • Affiliations
      1 Key Laboratory of Basic and Applied Research of Beiyao, Ministry of Education, Heilongjiang Key Laboratory of Traditional Chinese Medicine and Natural Medicine Pharmacodynamic Material Bases, Heilongjiang University of Chinese Medicine, Harbin 150040, China
    doi: 10.19664/j.cnki.1002-2392.260046
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    灵芝是一种珍贵的药用真菌,在中医药和现代医学中均具有重要价值。中医认为灵芝具有补气安神、止咳平喘的功效。近年来,灵芝多糖作为灵芝的主要活性成分之一,因其表现出抗肿瘤、抗病毒、抗氧化、抗衰老等药理活性而备受关注。本文总结了灵芝多糖的化学结构及药理作用的研究现状,以期为灵芝的进一步开发利用提供参考。
    灵芝多糖  /  化学结构  /  药理作用  /  研究进展
    Ganoderma is a valuable medicinal fungus with significant importance in both traditional Chinese medicine and modern medical practices. Historically, it has been esteemed for its abilities to replenish Qi (vital energy), calm the mind, and alleviate cough and asthma. In recent years, polysaccharides extracted from Ganoderma have garnered considerable attention as one of its primary active constituents, owing to their diverse pharmacological activities, including anti - tumor, antiviral, antioxidant, and anti - aging effects. This review summarizes the current research on the chemical structures and pharmacological effects of Ganoderma polysaccharides, aiming to provide a reference for their further development and application.
    Ganoderma polysaccharides  /  Chemical structure  /  Pharmacological effects  /  Research progress
    井晓婕, 姜思亮, 夏永刚, 梁军. 灵芝多糖化学结构及药理作用研究进展. 中医药学报, 2026 , 54 (2) : 120 -128 . DOI: 10.19664/j.cnki.1002-2392.260046
    JING Xiaojie, JIANG Siliang, XIA Yonggang, LIANG Jun. Research Progress on Chemical Structure and Pharmacological Effects of Ganoderma Polysaccharides[J]. Acta Chinese Medicine and Pharmacology, 2026 , 54 (2) : 120 -128 . DOI: 10.19664/j.cnki.1002-2392.260046

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    doi: 10.19664/j.cnki.1002-2392.260046
    • 接收时间:2025-03-24
    • 首发时间:2026-09-09
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    Number of
    species
    占总种数比例
    Percentage of
    total species (%)

    Genus
    种数
    Number of
    species
    占总种数比例
    Percentage of total
    species (%)
    鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
    小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
    多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
    红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
    小菇属 Mycena 11 5.26
    光柄菇属 Pluteus 5 2.39
    红菇属 Russula 17 8.13
    栓菌属 Trametes 5 2.39
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