Article(id=1304438818552177202, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1304438800676048898, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260034, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1730736000000, receivedDateStr=2024-11-05, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1788932049643, onlineDateStr=2026-09-09, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1788932049643, onlineIssueDateStr=2026-09-09, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1788932049643, creator=13701087609, updateTime=1788932049643, updator=13701087609, issue=Issue{id=1304438800676048898, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='2', pageStart='1', pageEnd='128', issueExtLink='null', onlineDate='null', pubDate='1771516800000', pubDateStr='2026-02-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1788932045382, creator='13701087609', updateTime=1788934764784, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1304450206712483920, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1304438800676048898, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1304450206712483921, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1304438800676048898, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=58, endPage=62, ext={EN=ArticleExt(id=1304438818820612660, articleId=1304438818552177202, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Study on Differences in Clinical Blood Indicators Among Different TCM Syndromes of Infantile Cytomegalovirus Hepatitis, columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=Objective: To investigate the differences in clinical blood indicators among infants with cytomegalovirus(CMV) hepatitis of different Traditional Chinese Medicine (TCM) syndromes, providing reference for clinical syndrome differentiation.Methods: A total of 120 infants meeting the diagnostic criteria for cytomegalovirus hepatitis were consecutively enrolled from Beijing Children's Hospital, Capital Medical University, from Febuary 2022 to Febuary 2024, including 40 cases each of dampness - heat internal accumulation syndrome, spleen deficiency with dampness retention syndrome, and qi stagnation with blood stasis syndrome. Differences in red blood cell parameters, platelet parameters, coagulation function, and liver function indicators were compared among the syndromes.Results: No significant differences were found in gender or age among the groups (P >0.05). The disease duration was longer in the spleen deficiency with dampness retention group and qi stagnation with blood stasis group compared to the dampness- heat internal accumulation group (P < 0.01). Regarding liver function, the qi stagnation with blood stasis group had higher GGT levels than the dampness - heat internal accumulation group (P <0.01), while the spleen deficiency with dampness retention group showed higher ALT levels (P <0.01). Both spleen deficiency with dampness retention and qi stagnation with blood stasis groups exhibited higher AST, TBIL, DBIL, and TBA levels than the dampness - heat internal accumulation group (P <0.05, P < 0.01). The qi stagnation with blood stasis group had higher TBIL, DBIL, and TBA levels than the spleen deficiency with dampness retention group (P <0.01). In red blood cell parameters, the spleen deficiency with dampness retention and qi stagnation with blood stasis groups showed lower RBC, HGB, and HCT but higher RDW compared to the dampness - heat internal accumulation group (P <0.05, P < 0.01). Platelet analysis revealed higher PLT in the qi stagnation with blood stasis group than in the spleen deficiency with dampness retention group (P <0.01). Coagulation tests demonstrated longer PT and higher INR in the qi stagnation with blood stasis group(P < 0.01) but lower FIB (P <0.05) versus the dampness - heat internal accumulation group. The spleen deficiency with dampness retention group had prolonged APTT (P < 0.05).Conclusion: Significant differences exist in blood indicators among different TCM syndromes of infantile cytomegalovirus hepatitis, providing a theoretical basis for clinical syndrome differentiation., authors=GUO Ziyun1 , DU Lina1 , QIU Mengyao2 , XIE Xiaoxuan1 , YANG Yan1 , authorsList=GUO Ziyun, DU Lina, QIU Mengyao, XIE Xiaoxuan, YANG Yan, authorCompany=1 Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China; 目的： 探讨不同中医证型婴儿巨细胞病毒（CMV）肝炎患儿临床血液指标的差异，为婴儿巨细胞病毒肝炎临床辨证提供参考依据。 方法： 连续收集2022年2月—2024年2月首都医科大学附属北京儿童医院符合婴儿巨细胞病毒肝炎诊断标准的湿热内蕴证、脾虚湿困证与气滞血瘀证患儿各40例，比较各证型患儿红细胞、血小板参数、凝血功能和肝功能等指标的差异。 结果： 各组间性别、年龄比较差异无统计学意义（P > 0.05）；脾虚湿困组、气滞血瘀组病程长于湿热内蕴组，差异有统计学意义（P < 0.01）；各组肝功能比较，气滞血瘀组GGT高于湿热内蕴组，差异有统计学意义（P < 0.01）；脾虚湿困组ALT高于湿热内蕴组，差异有统计学意义（P < 0.01）；脾虚湿困组、气滞血瘀组AST、TBIL、DBIL、TBA均高于湿热内蕴组，差异有统计学意义（P < 0.05，P < 0.01）；气滞血瘀组TBIL、DBIL、TBA均高于脾虚湿困组，差异有统计学意义（P < 0.01）；各组红细胞参数比较，脾虚湿困组和气滞血瘀组RBC、HGB、HCT均低于湿热内蕴组，差异有统计学意义（P < 0.01）；脾虚湿困组和气滞血瘀组RDW均高于湿热内蕴组，差异有统计学意义（P < 0.05，P < 0.01）；各组血小板参数比较，气滞血瘀组PLT高于脾虚湿困组，差异有统计学意义（P < 0.01）；各组凝血指标比较，气滞血瘀组PT、INR均高于湿热内蕴组，差异有统计学意义（P <0.01）；气滞血瘀组FIB低于湿热内蕴组，差异有统计学意义（P < 0.05）；脾虚湿困组APTT高于湿热内蕴组，差异有统计学意义（P < 0.05）。 结论： 婴儿巨细胞病毒肝炎患儿不同证型的血液指标存在差异，可为临床辨证提供理论依据。, authors=郭紫云1 , 杜丽娜1 , 邱梦瑶2 , 谢晓暄1 , 杨燕1 , authorsList=郭紫云, 杜丽娜, 邱梦瑶, 谢晓暄, 杨燕, authorCompany=1 国家儿童医学中心/首都医科大学附属北京儿童医院，北京 100045;
中医药学报
|临床研究
2026
, 54
(2) :
58
-62
婴儿巨细胞病毒肝炎不同中医证型临床血液指标的差异研究
全屏
郭紫云1 , 杜丽娜1 , 邱梦瑶2 , 谢晓暄1 , 杨燕1
作者信息
1 国家儿童医学中心/首都医科大学附属北京儿童医院，北京 100045;
通讯作者:
* 杨燕（1965-），女，博士，主任医师，从事儿童消化系统疾病诊治的相关研究。
作者简介:
郭紫云（1996-），女，博士研究生，从事儿童消化系统疾病诊治的相关研究。
Study on Differences in Clinical Blood Indicators Among Different TCM Syndromes of Infantile Cytomegalovirus Hepatitis
GUO Ziyun1 , DU Lina1 , QIU Mengyao2 , XIE Xiaoxuan1 , YANG Yan1
Affiliations
1 Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China;
doi: 10.19664/j.cnki.1002-2392.260034
文章导航
目的： 探讨不同中医证型婴儿巨细胞病毒（CMV）肝炎患儿临床血液指标的差异，为婴儿巨细胞病毒肝炎临床辨证提供参考依据。 方法： 连续收集2022年2月—2024年2月首都医科大学附属北京儿童医院符合婴儿巨细胞病毒肝炎诊断标准的湿热内蕴证、脾虚湿困证与气滞血瘀证患儿各40例，比较各证型患儿红细胞、血小板参数、凝血功能和肝功能等指标的差异。 结果： 各组间性别、年龄比较差异无统计学意义（P > 0.05）；脾虚湿困组、气滞血瘀组病程长于湿热内蕴组，差异有统计学意义（P < 0.01）；各组肝功能比较，气滞血瘀组GGT高于湿热内蕴组，差异有统计学意义（P < 0.01）；脾虚湿困组ALT高于湿热内蕴组，差异有统计学意义（P < 0.01）；脾虚湿困组、气滞血瘀组AST、TBIL、DBIL、TBA均高于湿热内蕴组，差异有统计学意义（P < 0.05，P < 0.01）；气滞血瘀组TBIL、DBIL、TBA均高于脾虚湿困组，差异有统计学意义（P < 0.01）；各组红细胞参数比较，脾虚湿困组和气滞血瘀组RBC、HGB、HCT均低于湿热内蕴组，差异有统计学意义（P < 0.01）；脾虚湿困组和气滞血瘀组RDW均高于湿热内蕴组，差异有统计学意义（P < 0.05，P < 0.01）；各组血小板参数比较，气滞血瘀组PLT高于脾虚湿困组，差异有统计学意义（P < 0.01）；各组凝血指标比较，气滞血瘀组PT、INR均高于湿热内蕴组，差异有统计学意义（P <0.01）；气滞血瘀组FIB低于湿热内蕴组，差异有统计学意义（P < 0.05）；脾虚湿困组APTT高于湿热内蕴组，差异有统计学意义（P < 0.05）。 结论： 婴儿巨细胞病毒肝炎患儿不同证型的血液指标存在差异，可为临床辨证提供理论依据。
Objective: To investigate the differences in clinical blood indicators among infants with cytomegalovirus(CMV) hepatitis of different Traditional Chinese Medicine (TCM) syndromes, providing reference for clinical syndrome differentiation.Methods: A total of 120 infants meeting the diagnostic criteria for cytomegalovirus hepatitis were consecutively enrolled from Beijing Children's Hospital, Capital Medical University, from Febuary 2022 to Febuary 2024, including 40 cases each of dampness - heat internal accumulation syndrome, spleen deficiency with dampness retention syndrome, and qi stagnation with blood stasis syndrome. Differences in red blood cell parameters, platelet parameters, coagulation function, and liver function indicators were compared among the syndromes.Results: No significant differences were found in gender or age among the groups (P >0.05). The disease duration was longer in the spleen deficiency with dampness retention group and qi stagnation with blood stasis group compared to the dampness- heat internal accumulation group (P < 0.01). Regarding liver function, the qi stagnation with blood stasis group had higher GGT levels than the dampness - heat internal accumulation group (P <0.01), while the spleen deficiency with dampness retention group showed higher ALT levels (P <0.01). Both spleen deficiency with dampness retention and qi stagnation with blood stasis groups exhibited higher AST, TBIL, DBIL, and TBA levels than the dampness - heat internal accumulation group (P <0.05, P < 0.01). The qi stagnation with blood stasis group had higher TBIL, DBIL, and TBA levels than the spleen deficiency with dampness retention group (P <0.01). In red blood cell parameters, the spleen deficiency with dampness retention and qi stagnation with blood stasis groups showed lower RBC, HGB, and HCT but higher RDW compared to the dampness - heat internal accumulation group (P <0.05, P < 0.01). Platelet analysis revealed higher PLT in the qi stagnation with blood stasis group than in the spleen deficiency with dampness retention group (P <0.01). Coagulation tests demonstrated longer PT and higher INR in the qi stagnation with blood stasis group(P < 0.01) but lower FIB (P <0.05) versus the dampness - heat internal accumulation group. The spleen deficiency with dampness retention group had prolonged APTT (P < 0.05).Conclusion: Significant differences exist in blood indicators among different TCM syndromes of infantile cytomegalovirus hepatitis, providing a theoretical basis for clinical syndrome differentiation.
Cytomegalovirus hepatitis
/
TCM syndrome
/
Clinical indicators
郭紫云, 杜丽娜, 邱梦瑶, 谢晓暄, 杨燕.
婴儿巨细胞病毒肝炎不同中医证型临床血液指标的差异研究.
中医药学报,
2026
, 54
(2)
: 58
-62
.
DOI: 10.19664/j.cnki.1002-2392.260034
GUO Ziyun, DU Lina, QIU Mengyao, XIE Xiaoxuan, YANG Yan.
Study on Differences in Clinical Blood Indicators Among Different TCM Syndromes of Infantile Cytomegalovirus Hepatitis[J].
Acta Chinese Medicine and Pharmacology ,
2026
, 54
(2)
: 58
-62
.
DOI: 10.19664/j.cnki.1002-2392.260034
2026年第54卷第2期
PDF下载
11
2
引用本文
BibTeX
文章信息
doi: 10.19664/j.cnki.1002-2392.260034
接收时间：2024-11-05
首发时间：2026-09-09
https://castjournals.cast.org.cn/joweb/zyyxb/CN/10.19664/j.cnki.1002-2392.260034
引用本文
BibTeX
2种不同金属材料的力学参数
科 属数 种数 占总种数比例 属 种数 占总种数比例 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
关闭全屏
BibTeX
EndNote
RefWorks
TxT
PDF下载
全屏
11
2
关闭全屏
北京市海淀区学院南路86号
010-62199257（仅加盟咨询）
qkjq@cast.org.cn
