Article(id=1303760941858976292, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1303760924272259535, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260063, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1742659200000, receivedDateStr=2025-03-23, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1788770431246, onlineDateStr=2026-09-07, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1788770431246, onlineIssueDateStr=2026-09-07, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1788770431246, creator=13041195026, updateTime=1788770431246, updator=13041195026, issue=Issue{id=1303760924272259535, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='3', pageStart='1', pageEnd='125', issueExtLink='null', onlineDate='null', pubDate='1773936000000', pubDateStr='2026-03-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1788770427052, creator='13041195026', updateTime=1788934400812, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1304448680157803505, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1303760924272259535, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1304448680157803506, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1303760924272259535, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=96, endPage=101, ext={EN=ArticleExt(id=1303760942190326310, articleId=1303760941858976292, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Effect of Zhilou Sukang Decoction on Wound Healing and Pain After Mixed Hemorrhoid Surgery, columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=Objective: To explore the effects of Zhilou Sukang Decoction on wound healing and inflammatory factors after mixed hemorrhoids surgery.Methods: A total of 133 patients with mixed hemorrhoids who underwent surgical treatment at Xinrui Hospital in Xinwu District of Wuxi from January 2023 to June 2024 were selected and randomly divided into the control group (n=67) and the observation group (n =66). The control group was given conventional Western medical treatment. On the basis of the treatment of the control group, the observation group was given hemorrhoid fistula Zhilou Sukang Decoction sitz bath. Both groups were intervened for 2 weeks. The healing efficacy, pain degree, anal distension, quality of life, wound area, granulation tissue growth score, inflammatory factors and incidence of adverse reactions were compared between the two groups. Result: In the control group of wound healing, the total effective rate of the observation group (93.94%) was significantly higher than that of the control group (74.63%) (P <0.05) ; One day after the treatment, the wound pain in the observation group was significantly relieved after each sitz bath. In the first week of treatment, the wound pain was more obvious in the control group, while the pain improvement effect was significant in the observation group after applying the sitz bath formula. From the second week, the wound pain in the observation group showed a continuous decreasing trend. In terms of the quantitative comparison of pain, the VAS score of the observation group decreased extremely significantly, and the VAS scores at each stage after treatment were significantly lower than those of the control group (all P < 0.05). After treatment, all pain indicators in both groups decreased, and the improvement degree of pain attack frequency and duration in the observation group was significantly better than that in the control group (all P < 0.05). After the treatment, the scores of the feeling of heaviness in both groups decreased. The observation group was significantly better than the control group in relieving the feeling of heaviness (all P < 0.05). After the treatment, the WHOQOL - BREF scores of both groups increased, and the increase in the observation group was greater (P < 0.05). After 2 weeks of treatment, the wound area and granulation tissue growth score indicators in both groups were significantly improved compared with those before treatment, and the improvement amplitude in the observation group was significantly better than that in the control group (all P < 0.05). After 2 weeks of treatment, the levels of the above inflammatory factors in both groups were significantly lower than those before treatment, and the reduction amplitude in the observation group was significantly better than that in the control group (all P < 0.05). During the treatment period of the two groups, 2 cases of mild local pruritus occurred in the observation group (3.03%), and 1 case of skin redness after iodophor disinfection occurred in the control group(1.49%). There was no significant difference in the incidence of adverse reactions (P > 0.05).Conclusion: The application of Zhilou Sukang Decoction sitz bath combined with western medicine intervention for patients after mixed hemorrhoids surgery can rapidly relieve wound pain, wound area, granulation tissue growth score, improve the feeling of heaving and inflammatory factor levels, and significantly enhance the wound healing effect, therefore, it is worthy of vigorous clinical promotion., authors=CHEN Lin¹, ZHU Weirong¹, CUI Mengdi², authorsList=CHEN Lin, ZHU Weirong, CUI Mengdi, authorCompany=1 Xinrui Hospital, Xinwu District, Wuxi 214111, China;
2 School of Acupuncture - Moxibustion and Tuina College, School of Health Preservation and Rehabilition, Nanjing University of Chinese Medicine, Nanjing 210023, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1303760942098051621, articleId=1303760941858976292, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=痔瘘速康汤对混合痔术后创面愈合效果及疼痛的影响, columnId=1303760933084484510, journalTitle=中医药学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=目的： 探究痔瘘速康汤对混合痔术后创面愈合效果及疼痛的影响。方法： 选取2023年1月—2024年6月于无锡市新吴区新瑞医院行手术治疗的133例混合痔患者，随机分为对照组（67例）和观察组（66例）。给予对照组常规西医治疗，在对照组治疗基础上，予以观察组痔瘘速康汤坐浴，两组均干预2周。对比两组愈合疗效、疼痛程度、肛门坠胀感、生活质量、创面面积、肉芽组织生长评分、炎症因子和不良反应发生率。结果： 创面愈合方面，观察组总有效率93.94% （62/66）明显高于对照组的74.63%（50/67），两组比较差异有统计学意义（P < 0.05）；治疗后，观察组在每次坐浴后创面疼痛均显著减轻（P < 0.05）；治疗首周，对照组创面疼痛较为明显，而观察组应用坐浴方后疼痛改善效果显著（P <0.05）；自第2周起，观察组创面疼痛呈持续减轻趋势（P < 0.05）；在疼痛量化对比方面，观察组VAS评分下降显著（P < 0.05），且治疗后各阶段VAS评分均明显低于对照组（P < 0.01）；治疗后，两组各项疼痛指标均下降（P < 0.05），且观察组在疼痛发作频率和持续时间的改善程度上显著优于对照组（P <0.01）；治疗后，两组坠胀感分数均降低（P < 0.05），观察组在缓解坠胀感显著优于对照组（P < 0.01）；治疗后，两组WHOQOL - BREF评分都有所上升（P < 0.05），观察组提升幅度更大（P < 0.01）；治疗2周后，两组创面面积、肉芽组织生长评分指标均较治疗前显著改善（P < 0.05），且观察组改善幅度显著优于对照组（P < 0.01）；治疗2周后，两组炎症因子水平均较治疗前显著降低（P < 0.05），且观察组降低幅度显著优于对照组（P < 0.01）；两组治疗期间观察组出现 2例局部轻微瘙痒（3.03%），对照组出现1例碘伏消毒后皮肤发红（1.49%），不良反应发生率比较，差异无统计学意义（P > 0.05）。结论： 对混合痔术后患者应用痔瘘速康汤坐浴联合西药干预，可迅速缓解患者创面疼痛、创面面积、肉芽组织生长评分，改善坠胀感和炎症因子水平，同时可显著提升创面愈合效果，值得临床大力推广。, authors=陈琳¹, 朱伟嵘¹, 崔梦迪², authorsList=陈琳, 朱伟嵘, 崔梦迪, authorCompany=1. 无锡市新吴区新瑞医院，江苏 无锡 214111;
2. 南京中医药大学针灸推拿学院·养生康复学院，江苏 南京 210023, correspAuthors=* 崔梦迪（1988-），女，博士，主治医师，主要从事中药外治法在创伤修复中的应用与机制研究。, authorNote=陈琳（1987-），男，硕士，主治医师，主要从事中西医结合及手术治疗各种肛门直肠良性疾病研究。, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=nNiF4AMZgF7hDeQeRVOtug==, pdfFileSize=1219340, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=国家自然科学基金项目 (81904205))}, authors=null, keywords=[Keyword(id=1304742901423043328, tenantId=1146029695717560320, journalId=1302318977290174537, articleId=1303760941858976292, language=CN, orderNo=1, keyword=混合痔术), Keyword(id=1304742901494346497, tenantId=1146029695717560320, journalId=1302318977290174537, articleId=1303760941858976292, language=CN, orderNo=2, keyword=痔瘘速康汤), Keyword(id=1304742901578232578, 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