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2 Jiangsu Chinese Medicine Clinical Innovation Center of Obstetrics, Gynecology and Reproduction, Nanjing 210029, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1303760941716362180, articleId=1303760941456315331, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=苍附导痰汤治疗多囊卵巢综合征的研究进展, columnId=1303760941036888710, journalTitle=中医药学报, columnName=研究进展, runingTitle=null, highlight=null, articleAbstract=

多囊卵巢综合征（PCOS）是一种常见的生殖内分泌和代谢障碍疾病，其患病率逐年增高，发病机制尚未明确，是临床治疗中的一大挑战。《叶天士女科诊治秘方》所载苍附导痰汤治疗PCOS效果显著。苍附导痰汤可通过干预磷脂酰肌醇3 -激酶/蛋白激酶B（PI3K/Akt）、核转录因子 - κB（NF - κB）、腺苷酸活化蛋白激酶（AMPK）、丝裂原活化蛋白激酶（MAPK）、转化生长因子- β1/Smad同源物3 （TGF- β1/Smad3）等信号通路，发挥治疗作用。在临床应用上，单独使用苍附导痰汤或加减方或联合西药或联合外治法，均可改善PCOS患者的临床症状，安全有效，值得临床推广应用。本文从苍附导痰汤的作用机制以及临床研究现状两个方面，系统总结了其治疗PCOS的研究进展，以期为其进一步实验研究及临床应用推广提供参考。

, authors=范冰莹^1,2, 商婷婷^1,2, 庄子荀^1,2, 陈雯玥^1,2, 任青玲^1,2, authorsList=范冰莹, 商婷婷, 庄子荀, 陈雯玥, 任青玲, authorCompany=1. 南京中医药大学附属医院，江苏 南京 210029;
2. 江苏省中医妇产生殖临床医学创新中心，江苏 南京 210029, correspAuthors=* 任青玲（1969-），女，博士，教授，博士生导师，研究方向：中医药防治多囊卵巢综合征及宫颈癌前疾病研究。, authorNote=范冰莹（2000-），女，硕士研究生，研究方向：妇科生殖内分泌疾病的基础与临床研究。, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=NnPnc9nJUb/CGyZV6DFrIA==, pdfFileSize=2286002, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=国家自然科学基金项目 (82104904); 江苏省中医药管理局中医临床医学创新中心研究项目 (ZX202102); 江苏省研究生实践创新计划 (SJCX23_0776))}, authors=null, keywords=[Keyword(id=1304742902274482785, tenantId=1146029695717560320, journalId=1302318977290174537, articleId=1303760941456315331, language=CN, orderNo=1, keyword=多囊卵巢综合征), Keyword(id=1304742902329008738, tenantId=1146029695717560320, journalId=1302318977290174537, articleId=1303760941456315331, 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