Article(id=1305171239174169345, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1305171206701871960, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260190, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1760544000000, receivedDateStr=2025-10-16, revisedDate=1779206400000, revisedDateStr=2026-05-20, acceptedDate=null, acceptedDateStr=null, onlineDate=1789106672328, onlineDateStr=2026-09-11, pubDate=1789833600000, pubDateStr=2026-09-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789106672328, onlineIssueDateStr=2026-09-11, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789106672328, creator=13701087609, updateTime=1789106672328, updator=13701087609, issue=Issue{id=1305171206701871960, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='9', pageStart='1', pageEnd='133', issueExtLink='null', onlineDate='null', pubDate='1789833600000', pubDateStr='2026-09-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1789106664586, creator='13701087609', updateTime=1789106805687, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1305171798593663109, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1305171206701871960, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1305171798593663110, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1305171206701871960, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=111, endPage=115, ext={EN=ArticleExt(id=1305171239333552898, articleId=1305171239174169345, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Observation on the Efficacy of Acupuncture with Tiaogan Xifeng Therapy Combined with Conventional Western Medicine in Children with Tourette Syndrome (Spleen Deficiency and Liver Hyperactivity Pattern), columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To explore the clinical efficacy of Tiaogan Xifeng (Liver-Regulating and Wind-Extinguishing) Acupuncture Therapy combined with conventional western medicine to treat children with tourette's syndrome (spleen deficiency and liver hyperactivity syndrome).
Methods: 88 children with tourette's syndrome (spleen deficiency and liver hyperactivity syndrome) who were treated in Kaifeng Hospital of Traditional Chinese Medicine from September 2022 to January 2025 were selected for the study, and they were randomly divided into two groups, and the each group had 44 cases. The western medicine group received conventional western medicine therapy treatment, while the combination group received Tiaogan Xifeng Acupuncture Therapy on the basis of western medicine group. The traditional Chinese medicine syndrome scores, severity of symptoms [Yale global tic severity scale (YGTSS)], and neurotransmitter levels [Norepinephrine (NE), γ-aminobutyric acid (GABA), dopamine (DA)] of children before and after treatment were compared in two groups, and the clinical efficacy and adverse drug reactions in two groups of children were compared.
Results: After treatment, the traditional Chinese medicine syndrome score, YGTSS score and the levels of NE and DA in two groups decreased (P < 0. 05), and those in the combination group were lower (P < 0.05). After treatment, the level of GABA in two groups increased (P <0.05), and that in combination group was higher (P < 0.05). The total effective rate of treatment in the combination group was higher than that in the western medicine group (P < 0.05). There was no statistically significant difference in the incidence of adverse reactions among in two groups (P > 0.05).
Conclusion: The Tiaogan Xifeng Acupuncture Therapy combined with conventional western medicine to treat children with tourette's syndrome (spleen deficiency and liver hyperactivity syndrome) has good clinical efficacy, and the patient's condition and neurotransmitter levels have significantly improved, and the risk of adverse reactions in children is low.
, authors=Haihong YUAN
1, Qianyi ZHAO
2, Tiantian WANG
1, Zihua GUO
1, *, Ruixing LI
2, authorsList=Haihong YUAN, Qianyi ZHAO, Tiantian WANG, Zihua GUO, Ruixing LI, authorCompany=null, correspAuthors=Zihua GUO, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1305171239727817475, articleId=1305171239174169345, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=调肝熄风法针刺联合常规西医治疗多发性抽动症(脾虚肝亢证)患儿的效果观察, columnId=1303760933084484510, journalTitle=中医药学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的： 探讨调肝熄风法针刺联合常规西医治疗多发性抽动症（脾虚肝亢证）患儿的临床疗效。
方法： 选取2022年9月—2025年1月在开封市中医院治疗的多发性抽动症（脾虚肝亢证）患儿88例，随机分为西医组和联合组，每组44例。西医组采用常规西医疗法，联合组在西医组的基础上增加调肝熄风法针刺治疗。比较两组患儿治疗前后的中医证候积分、病情严重程度［耶鲁抽动症整体严重度量表（YGTSS）］、神经递质水平［去甲肾上腺素（NE）、γ-氨基丁酸（GABA）、多巴胺（DA）］，并比较两组患儿的临床疗效和药物不良反应。
结果： 治疗后，两组的中医证候积分、YGTSS评分、NE和DA水平均降低（P < 0.05，P < 0.01），且联合组更低（P < 0.05，P < 0.01）。治疗后，两组的GABA水平均升高（P <0.05），且联合组更高（P < 0.05）。联合组治疗总有效率高于西医组（P < 0.05）。两组不良反应发生率差异无统计学意义（P > 0.05）。
结论： 采用调肝熄风法针刺联合常规西医治疗多发性抽动症（脾虚肝亢证）患儿的临床疗效良好，患儿病情和神经递质水平得到明显改善，且不良反应的发生风险低。
, authors=袁海红
1, 赵倩义
2, 王甜甜
1, 郭子华
1, *, 李瑞星
2, authorsList=袁海红, 赵倩义, 王甜甜, 郭子华, 李瑞星, authorCompany=null, correspAuthors=郭子华, authorNote=
袁海红（1982-），男，副主任中医师，从事中医治疗儿童抽动症相关研究。
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* 郭子华（1982 -），男，硕士，副主任医师，从事脑病治疗相关研究。
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