Article(id=1305171215405048384, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1305171206701871960, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260184, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1741881600000, receivedDateStr=2025-03-14, revisedDate=1767715200000, revisedDateStr=2026-01-07, acceptedDate=null, acceptedDateStr=null, onlineDate=1789106666661, onlineDateStr=2026-09-11, pubDate=1789833600000, pubDateStr=2026-09-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789106666661, onlineIssueDateStr=2026-09-11, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789106666661, creator=13701087609, updateTime=1789106666661, updator=13701087609, issue=Issue{id=1305171206701871960, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='9', pageStart='1', pageEnd='133', issueExtLink='null', onlineDate='null', pubDate='1789833600000', pubDateStr='2026-09-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1789106664586, creator='13701087609', updateTime=1789106805687, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1305171798593663109, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1305171206701871960, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1305171798593663110, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1305171206701871960, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=76, endPage=80, ext={EN=ArticleExt(id=1305171215589597761, articleId=1305171215405048384, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Exploration of the TCM Syndrome Efficacy of Yushen Zhuyun Formula in Treating Infertility and Its Effect on Endometrial Thickness Based on the TCM Theory of "Kidney Governing Reproduction", columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: Based on the theory of" Kidney Governing Reproduction", the clinical efficacy of Yushen Zhuyun Formula in treating ovulation dysfunction infertility was discussed.
Methods: A total of 102 patients with ovulatory infertility admitted to Nanyang Second General Hospital from January 2022 to January 2024 were selected and randomly divided into a control group (conventional western medicine treatment) and a study group (conventional western medicine + treatment of Yushen Zhuyun Formula) with 51 cases in each group. Record and compare the clinical curative effect of TCM syndrome integral, the two groups, ultrasonic index, sex hormone [serum luteinizing hormone (LH), estradiol (E2), follicle-stimulating hormone (FSH)] level and incidence of adverse reactions.
Results: After treatment, two groups of TCM syndrome integral are lower than before the treatment, and the team was lower (P <0.05). After treatment, clinical treatment group total effective rate was 92.16%, 76.47% higher than the control group (P <0.05). After treatment, the number of dominant follicles was more in both groups than before treatment, and more in the study group (P <0. 05). Two groups of dominant follicle diameter and the thickness of endometrium is higher than before the treatment, and the group is higher (P < 0.05). After treatment, two groups of LH, FSH level was reduced, the E2 levels are higher, and larger variations in team (P < 0.05). During the treatment period, the incidence of adverse reactions in the study group was 5.82%, which was lower than that in the control group 15. 69% (P > 0.05). The natural pregnancy rate in the study group was 41.18%, which was higher than the 21.57% in the control group (P < 0.05).
Conclusion: The Yushen Zhuyun Formula, based on the theory of "Kidney Governing Reproduction", has significant effect on ovulation dysfunction infertility patients, can effectively promote follicle and endometrial development, regulate the recovery of sex hormone levels, with a low incidence of adverse reactions.
, authors=Shihui WANG
1, Chunlei CHANG
1, Shiling LI
1, Junmin LI
2, authorsList=Shihui WANG, Chunlei CHANG, Shiling LI, Junmin LI, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1305171215845450306, articleId=1305171215405048384, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=基于中医“肾主生殖”理论探讨育肾助孕方对肾虚型排卵障碍性不孕症的影响, columnId=1303760933084484510, journalTitle=中医药学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的： 基于中医“肾主生殖”理论探讨育肾助孕方治疗排卵障碍性不孕症（ODI）患者的临床效果。
方法： 选取2022年1月—2024年1月南阳市第二人民医院收治的ODI患者 102例，随机数字表法分为对照组（常规西药治疗）和研究组（常规西药+育肾助孕方治疗），每组 51例。记录并比较两组中医证候积分、临床疗效、超声指标、性激素［血清黄体生成素（LH）、雌二醇（E2）、卵泡刺激素（FSH）］水平、不良反应发生率及妊娠情况。
结果： 治疗后，两组中医证候积分均低于治疗前（P < 0.05），且研究组更低（P < 0.01）；治疗后，研究组临床治疗总有效率为92.16% （47/51），高于对照组76.47% （39/51） （P <0.05）；治疗后，两组优势卵泡个数比治疗前增加（P < 0.05），且研究组增加更多（P < 0.01）；两组优势卵泡直径和子宫内膜厚度高于治疗前（P < 0.05），且研究组更高（P < 0.01）；治疗后，两组LH、FSH水平均较治疗前降低，E2水平均升高（P < 0.05），且研究组变化幅度更大（P < 0.01）；治疗期间，研究组不良反应发生率为5.82% （3/51），低于对照组15.69% （8/51）（P > 0.05）；研究组自然妊娠率为41.18% （21/51），高于对照组21.57%（11/51）（P < 0.05）。
结论： 以“肾主生殖”理论为指导的育肾助孕方对ODI患者的疗效显著，可有效促进卵泡和子宫内膜发育，调节性激素水平恢复，且不良反应发生率低。
, authors=王诗会
1, 常春蕾
1, 李世玲
1, 李俊敏
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王诗会（1975-），女，副主任药师，从事中药新疗效相关研究。
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