Article(id=1307269506640933691, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1307269479684133809, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260149, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1735574400000, receivedDateStr=2024-12-31, revisedDate=1764000000000, revisedDateStr=2025-11-25, acceptedDate=null, acceptedDateStr=null, onlineDate=1789606938276, onlineDateStr=2026-09-17, pubDate=1784476800000, pubDateStr=2026-07-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789606938276, onlineIssueDateStr=2026-09-17, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789606938276, creator=13701087609, updateTime=1789606938276, updator=13701087609, issue=Issue{id=1307269479684133809, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='7', pageStart='1', pageEnd='128', issueExtLink='null', onlineDate='null', pubDate='1784476800000', pubDateStr='2026-07-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1789606931849, creator='13701087609', updateTime=1789606931849, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=103, endPage=108, ext={EN=ArticleExt(id=1307269506800317244, articleId=1307269506640933691, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Clinical Observation of Danggui Niantong Decoction Combined with Celecoxib in the Treatment of Cervical Spondylotic Radiculopathy with Wind-Damp-Heat Obstruction Syndrome, columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To evaluate the efficacy of celecoxib combined with Danggui Niantong Decoction in the treatment of cervical spondylotic radiculopathy Wind-Damp-Heat Obstruction syndrome).
Methods: A total of 98 patients with cervical radiculopathy (Wind-Damp-Heat Obstruction syndrome) admitted to the orthopedics and inpatient department of Huanggang Central Hospital from January 2023 to December 2023 were selected as the study objects, and were divided into 2 groups according to random number table method, with 49 cases each. The control group was treated with celecxib on the basis of cervical traction therapy, and the experimental group was treated with Danggui Niantong Decoction on the basis of control group for 4 weeks. The clinical efficacy, TCM symptom score, VAS scale score, NDI questionnaire, CASCS scale score, serum inflammatory indicators IL-1β, IL-6β, TNF-αlevel and incidence of adverse reactions were compared between the two groups.
Results: The total effective rate of experimental group after treatment was significantly higher than that of control group (P < 0.05). After treatment, TCM symptom score of two groups was significantly decreased, and the test group was lower than the control group(P < 0.05). VAS and NDI scores after treatment were lower than before treatment, CASCS scores were higher than before treatment, and the change range of experimental group was higher than that of control group (P <0.05). The serum levels of IL-1β, IL-6β and TNF-αin 2 groups after treatment were lower than before treatment, and the experimental group was lower than the control group(P < 0.05).
Conclusion: Danggui Niantong Decoction combined with celecxib has a good effect in the treatment of cervical spondylopathy patients with rheumatic heat arthralgia nerve root type, which can significantly improve cervical spine function and clinical symptoms, reduce the level of pain and inflammatory factors, and is safe, worthy of clinical promotion.
, authors=Ke AI, Lei WANG
*, Jun YANG, Jieneng CHEN, authorsList=Ke AI, Lei WANG, Jun YANG, Jieneng CHEN, authorCompany=null, correspAuthors=Lei WANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1307269507098112829, articleId=1307269506640933691, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=当归拈痛汤联合塞来昔布治疗风湿热痹型神经根型颈椎病的临床观察, columnId=1303760933084484510, journalTitle=中医药学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的： 评价塞来昔布联合当归拈痛汤在神经根型颈椎病（风湿热痹型）治疗中的效果。
方法： 选取2023年1月—2023年12月黄冈市中心医院骨伤科门诊及住院部收治的神经根型颈椎病（风湿热痹型）患者98例，按照随机数表法将其分为对照组和试验组，每组49例。对照组在颈椎牵引疗法基础上加用塞来昔布治疗，试验组则在对照组的基础上加用当归拈痛汤加减，共治疗4周。比较两组临床疗效、中医症状积分、VAS量表评分、NDI问卷、CASCS量表评分、血清炎症指标IL-1β、IL-6β、TNF-α水平及不良反应发生率。
结果： 试验组患者治疗后的总有效率高于对照组（P < 0.05）。两组患者治疗后中医症状积分明显降低（P < 0.05），且试验组低于对照组（P < 0.05）。两组患者治疗后VAS、NDI评分均低于治疗前（P < 0.05），而CASCS评分高于治疗前（P < 0.05），且试验组改变幅度大于对照组（P <0.05）。两组患者治疗后血清IL-1β、IL-6β、TNF-α浓度水平均低于治疗前（P < 0.05），且试验组低于对照组（P < 0.05）。
结论： 当归拈痛汤联合塞来昔布治疗风湿热痹型神经根型颈椎病患者效果较好，能够明显改善患者颈椎功能与临床症状，降低疼痛与炎性因子水平，且安全性较高，值得临床推广。
, authors=艾柯, 王雷
*, 杨军, 陈杰能, authorsList=艾柯, 王雷, 杨军, 陈杰能, authorCompany=null, correspAuthors=王雷, authorNote=
艾柯（1981-），男，主治医师，研究方向：关节炎等骨科疾病。
, correspAuthorsNote=
* 王雷（1978 -），男，博士，主任医师，研究方向：神经胶质瘤的基础与临床研究。
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艾柯（1981-），男，主治医师，研究方向：关节炎等骨科疾病。
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艾柯（1981-），男，主治医师，研究方向：关节炎等骨科疾病。
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