Article(id=1307269492401267539, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1307269479684133809, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260145, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1733673600000, receivedDateStr=2024-12-09, revisedDate=1759161600000, revisedDateStr=2025-09-30, acceptedDate=null, acceptedDateStr=null, onlineDate=1789606934881, onlineDateStr=2026-09-17, pubDate=1784476800000, pubDateStr=2026-07-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789606934881, onlineIssueDateStr=2026-09-17, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789606934881, creator=13701087609, updateTime=1789606934881, updator=13701087609, issue=Issue{id=1307269479684133809, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='7', pageStart='1', pageEnd='128', issueExtLink='null', onlineDate='null', pubDate='1784476800000', pubDateStr='2026-07-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1789606931849, creator='13701087609', updateTime=1789606931849, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=77, endPage=82, ext={EN=ArticleExt(id=1307269492577428308, articleId=1307269492401267539, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Observation on the Efficacy of Warm Needling at Periumbilical Points Combined with Jianpi Anshen Decoction in Treating Chronic Insomnia with Heart-Spleen Deficiency Syndrome, columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To observe the effect of Jianpi Anshen Decoction combined with warm acupuncture at Periumbilical Four-Sided Points on the treatment of patients with chronic insomnia heart-spleen deficiency syndrome.
Methods: A total of 92 patients with chronic insomnia heart-spleen deficiency syndrome treated in Ma'anshan Shiqiye Hospital from January 2020 to September 2024 were selected and divided into experimental group (n=46) and control group (n = 46) by random number table method. The control group was treated with warm acupuncture at Periumbilical Four-Sided Points, the experimental group received Jianpi Anshen decoction on the basis of the control group. Both groups were treated for 3 months. The TCM symptom score, sleep structure, insomnia degree, sleep quality, clinical efficacy, neurotransmitter and adverse reactions were compared between the two groups.
Results: After treatment, the scores of TCM syndrome, wake after sleep on set (WASO), sleep latency (SOL), insomnia Severity Index Scale (ISI) and Pittsburgh Sleep Quality Index (PSQI) were all decreased in two groups, and the experimental group was lower (P < 0.05). After treatment, total sleep time (TST) and sleep efficiency (SE) were increased in both groups, and higher in the experimental group (P < 0.05). The experimental group with total effective rate (93.65%) was higher than the control group (82.61%) (P <0.05). After treatment, serum 5-hydroxytryptamine (5-HT) and glycated serum albumin (GA) levels were increased in both groups, and higher in experimental group (P < 0.05). After treatment, serum dopamine (DA) level was decreased in both groups, and lower in experimental group (P < 0.05). During the treatment period, there were no obvious adverse reactions in both groups. Within 3 months of treatment, there was no significant difference in recurrence rate between the two groups (P > 0.05).
Conclusion: Jianpi Anshen Decoction combined with warm acupuncture at Periumbilical Four-Sided Points in the treatment of chronic insomnia patients with heart-spleen deficiency syndrome is effective, can improve the sleep structure and sleep quality of patients, reduce insomnia symptoms, regulate neurotransmitters, good safety, and good short-term prognosis.
, authors=Wenwen WU, Mingyu ZHOU, Jinxian ZHANG, Yinzhen ZHU, authorsList=Wenwen WU, Mingyu ZHOU, Jinxian ZHANG, Yinzhen ZHU, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1307269492900389717, articleId=1307269492401267539, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=温针灸脐周四边穴联合健脾安神汤治疗慢性失眠心脾两虚证患者的疗效观察, columnId=1303760933084484510, journalTitle=中医药学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的： 观察慢性失眠心脾两虚证患者采用温针灸脐周四边穴联合健脾安神汤的治疗效果。
方法： 选取马鞍山十七冶医院2020年1月—2024年9月收诊的慢性失眠心脾两虚证患者92例，采用随机数字表法将其分为试验组与对照组，每组46例。对照组采用温针灸脐周四边穴治疗，试验组在对照组的基础上接受健脾安神汤治疗。两组均治疗3个月。比较两组患者的中医证候评分、睡眠结构、失眠程度、睡眠质量、临床疗效、神经递质及不良反应。
结果： 治疗后，两组中医证候评分、入睡后的觉醒（WASO）、睡眠潜伏期（SOL）、失眠严重指数量表（ISI）评分、匹兹堡睡眠质量指数（PSQI）评分均降低（P < 0.05），试验组更低（P < 0.05）。治疗后，两组总睡眠时间（TST）、睡眠效率（SE）均升高（P <0.05），试验组更高（P < 0.05）。试验组的总有效率为93.65% （44/46）高于对照组的82.61% （38/46），差异有统计学意义（P < 0.05）。治疗后，两组血清5-羟色胺（5-HT）、糖化血清白蛋白（GA）水平均升高（P < 0.05），试验组更高（P < 0.05）；治疗后，两组血清多巴胺（DA）水平均降低（P < 0.05），试验组更低（P < 0.05）。治疗期间，两组均未出现明显不良反应。治疗3个月内，两组复发率对比无明显差异（P > 0.05）。
结论： 健脾安神汤联合温针灸脐周四边穴治疗慢性失眠心脾两虚证患者疗效确切，可改善患者睡眠结构与睡眠质量，减轻失眠症状，调节神经递质，安全性良好，且短期预后良好。
, authors=吴雯雯, 周名誉, 张进先, 朱银珍, authorsList=吴雯雯, 周名誉, 张进先, 朱银珍, authorCompany=null, correspAuthors=null, authorNote=
吴雯雯（1990-），女，主治中医师，从事中医内科相关研究。
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吴雯雯（1990-），女，主治中医师，从事中医内科相关研究。
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吴雯雯（1990-），女，主治中医师，从事中医内科相关研究。
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