Article(id=1307269540434440210, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1307269516371719010, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260126, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1729267200000, receivedDateStr=2024-10-19, revisedDate=1752422400000, revisedDateStr=2025-07-14, acceptedDate=null, acceptedDateStr=null, onlineDate=1789606946333, onlineDateStr=2026-09-17, pubDate=1781884800000, pubDateStr=2026-06-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789606946333, onlineIssueDateStr=2026-09-17, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789606946333, creator=13701087609, updateTime=1789606946333, updator=13701087609, issue=Issue{id=1307269516371719010, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='6', pageStart='1', pageEnd='126', issueExtLink='null', onlineDate='null', pubDate='1781884800000', pubDateStr='2026-06-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1789606940596, creator='13701087609', updateTime=1789606940596, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=90, endPage=96, ext={EN=ArticleExt(id=1307269540803538963, articleId=1307269540434440210, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Clinical Observation of Buyang Huanwu Decoction Combined with "Shao's Five-Needle Technique" in Treating Unstable Angina Pectoris of Coronary Heart Disease, columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective:

To investigate the efficacy of Buyang Huanwu Decoction combined with "Shao's Five-Needle Technique" in treating unstable angina pectoris (UA) of coronary heart disease.

Methods:

Using a random number table method, 120 patients with UA of coronary heart disease admitted to Baoji Hospital of Traditional Chinese Medicine from January 2023 to July 2024 were divided into a decoction group, an acupuncture group, and a combination group, with 40 cases in each group. All three groups received conventional treatment. Additionally, the decoction group was treated with Buyang Huanwu Decoction, the acupuncture group was treated with "Shao's Five-Needle Technique," and the combination group was treated with Buyang Huanwu Decoction combined with "Shao's Five-Needle Technique." One treatment course consisted of 10 days, and all groups were treated for 2 courses. The clinical efficacy of angina pectoris, electrocardiogram efficacy, and adverse reactions were compared among the three groups. TCM syndrome scores, clinical symptoms, cardiac function, blood lipids, and serum inflammatory indicators were recorded before and after treatment in each group.

Results:

The overall comparison of the total clinical effective rates and total electrocardiogram effective rates among the three groups showed statistically significant differences (P <0.05). After treatment, the total TCM syndrome scores, clinical symptom-related indicators of angina pectoris, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), and serum levels of interleukin (IL)-6, IL-1β, high-sensitivity C-reactive protein (hs-CRP), and tumor necrosis factor-α(TNF-α) decreased in all three groups compared with those before treatment (P < 0.05). The combination group had lower total TCM syndrome scores, clinical symptoms of angina pectoris, TC, LDL-C, and serum inflammatory-related indicators than the decoction group and acupuncture group (P <0.05). After treatment, the cardiac ejection fraction (EF), stroke volume (SV), and high-density lipoprotein cholesterol (HDL-C) increased in all three groups compared with those before treatment (P < 0.05). The combination group had higher EF and SV than the decoction group and acupuncture group (P <0.05). There were no statistically significant differences in any indicators between the decoction group and the acupuncture group (P > 0.05). The comparison of the total incidence of adverse reactions among the three groups showed no statistically significant difference (P > 0.05).

Conclusion:

Buyang Huanwu Decoction combined with "Shao's Five-Needle Technique" is safe and effective in treating UA of coronary heart disease. It significantly improves angina symptoms and cardiac function, with notable lipid-regulating and anti-inflammatory effects.

, authors=Le ZHANG1, Lei ZHAO2, Jie ZHANG1, *, authorsList=Le ZHANG, Lei ZHAO, Jie ZHANG, authorCompany=null, correspAuthors=Jie ZHANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1307269541315244053, articleId=1307269540434440210, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=补阳还五汤联合“邵氏五针法”治疗冠心病不稳定型心绞痛的临床观察, columnId=1303760933084484510, journalTitle=中医药学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的:

探究补阳还五汤联合“邵氏五针法”治疗冠心病不稳定型心绞痛(UA)的疗效。

方法:

随机数字表法将2023年1月—2024年7月宝鸡市中医医院收治的120例冠心病UA患者分为汤剂组、针灸组与联合组,每组40例。3组均接受常规治疗,此外汤剂组加用补阳还五汤治疗,针灸组加用“邵氏五针法”治疗,联合组则加用补阳还五汤联合“邵氏五针法”治疗。1个疗程10 d,均治疗2个疗程。对比3组患者心绞痛临床疗效、心电图疗效及不良反应,记录各组治疗前后中医证候积分、临床症状、心功能、血脂及血清炎症指标。

结果:

3组临床总有效率、心电图总有效率整体对比差异有统计学意义(P <0.05)。治疗后,3组中医证候总积分、心绞痛临床症状相关指标、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)及血清白细胞介素(IL)-6、IL-1β、超敏C反应蛋白(hs-CRP)、肿瘤坏死因子-α(TNF-α)水平均较治疗前下降(P < 0.05),联合组中医证候总积分、心绞痛临床症状、TC、LDL-C及血清炎症相关指标均低于汤剂组、针灸组(P < 0.05)。治疗后,3组心脏射血分数(EF)、每搏输出量(SV)、高密度脂蛋白胆固醇(HDL-C)均较治疗前上升(P < 0.05),联合组EF、SV均大于汤剂组、针灸组(P < 0.05)。汤剂组与针灸组各指标对比,差异均无统计学意义(P > 0.05)。3组不良反应总发生率对比,差异无统计学意义(P > 0.05)。

结论:

补阳还五汤联合“邵氏五针法”治疗冠心病UA安全有效,能明显改善患者心绞痛症状及心功能,调脂、抑炎作用明显。

, authors=张乐1, 赵磊2, 张洁1, *, authorsList=张乐, 赵磊, 张洁, authorCompany=null, correspAuthors=张洁, authorNote=

张乐(1990-),男,主治医师,从事中医内科相关研究。

, correspAuthorsNote=
* 张洁(1990 -),女,硕士,主治医师,从事中医内科相关研究。
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补阳还五汤联合“邵氏五针法”治疗冠心病不稳定型心绞痛的临床观察
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张乐 1 , 赵磊 2 , 张洁 1, *
中医药学报 | 临床研究 2026,54(6): 90-96
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中医药学报 |临床研究 2026 , 54 (6) : 90 -96
补阳还五汤联合“邵氏五针法”治疗冠心病不稳定型心绞痛的临床观察
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张乐1, 赵磊2, 张洁1, *
作者信息
  • 1.宝鸡市中医医院,陕西 宝鸡 721006
  • 2.河北医科大学第四医院,河北 石家庄 050011
通讯作者:
* 张洁(1990 -),女,硕士,主治医师,从事中医内科相关研究。
作者简介:

张乐(1990-),男,主治医师,从事中医内科相关研究。

Clinical Observation of Buyang Huanwu Decoction Combined with "Shao's Five-Needle Technique" in Treating Unstable Angina Pectoris of Coronary Heart Disease
Le ZHANG1, Lei ZHAO2, Jie ZHANG1, *
Affiliations
  • 1.Baoji Hospital of Traditional Chinese Medicine, Baoji 721006, China
  • 2.The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China
出版时间: 2026-06-20 doi: 10.19664/j.cnki.1002-2392.260126
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目的:

探究补阳还五汤联合“邵氏五针法”治疗冠心病不稳定型心绞痛(UA)的疗效。

方法:

随机数字表法将2023年1月—2024年7月宝鸡市中医医院收治的120例冠心病UA患者分为汤剂组、针灸组与联合组,每组40例。3组均接受常规治疗,此外汤剂组加用补阳还五汤治疗,针灸组加用“邵氏五针法”治疗,联合组则加用补阳还五汤联合“邵氏五针法”治疗。1个疗程10 d,均治疗2个疗程。对比3组患者心绞痛临床疗效、心电图疗效及不良反应,记录各组治疗前后中医证候积分、临床症状、心功能、血脂及血清炎症指标。

结果:

3组临床总有效率、心电图总有效率整体对比差异有统计学意义(P <0.05)。治疗后,3组中医证候总积分、心绞痛临床症状相关指标、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)及血清白细胞介素(IL)-6、IL-1β、超敏C反应蛋白(hs-CRP)、肿瘤坏死因子-α(TNF-α)水平均较治疗前下降(P < 0.05),联合组中医证候总积分、心绞痛临床症状、TC、LDL-C及血清炎症相关指标均低于汤剂组、针灸组(P < 0.05)。治疗后,3组心脏射血分数(EF)、每搏输出量(SV)、高密度脂蛋白胆固醇(HDL-C)均较治疗前上升(P < 0.05),联合组EF、SV均大于汤剂组、针灸组(P < 0.05)。汤剂组与针灸组各指标对比,差异均无统计学意义(P > 0.05)。3组不良反应总发生率对比,差异无统计学意义(P > 0.05)。

结论:

补阳还五汤联合“邵氏五针法”治疗冠心病UA安全有效,能明显改善患者心绞痛症状及心功能,调脂、抑炎作用明显。

冠心病  /  不稳定型心绞痛  /  补阳还五汤  /  邵氏五针法
Objective:

To investigate the efficacy of Buyang Huanwu Decoction combined with "Shao's Five-Needle Technique" in treating unstable angina pectoris (UA) of coronary heart disease.

Methods:

Using a random number table method, 120 patients with UA of coronary heart disease admitted to Baoji Hospital of Traditional Chinese Medicine from January 2023 to July 2024 were divided into a decoction group, an acupuncture group, and a combination group, with 40 cases in each group. All three groups received conventional treatment. Additionally, the decoction group was treated with Buyang Huanwu Decoction, the acupuncture group was treated with "Shao's Five-Needle Technique," and the combination group was treated with Buyang Huanwu Decoction combined with "Shao's Five-Needle Technique." One treatment course consisted of 10 days, and all groups were treated for 2 courses. The clinical efficacy of angina pectoris, electrocardiogram efficacy, and adverse reactions were compared among the three groups. TCM syndrome scores, clinical symptoms, cardiac function, blood lipids, and serum inflammatory indicators were recorded before and after treatment in each group.

Results:

The overall comparison of the total clinical effective rates and total electrocardiogram effective rates among the three groups showed statistically significant differences (P <0.05). After treatment, the total TCM syndrome scores, clinical symptom-related indicators of angina pectoris, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), and serum levels of interleukin (IL)-6, IL-1β, high-sensitivity C-reactive protein (hs-CRP), and tumor necrosis factor-α(TNF-α) decreased in all three groups compared with those before treatment (P < 0.05). The combination group had lower total TCM syndrome scores, clinical symptoms of angina pectoris, TC, LDL-C, and serum inflammatory-related indicators than the decoction group and acupuncture group (P <0.05). After treatment, the cardiac ejection fraction (EF), stroke volume (SV), and high-density lipoprotein cholesterol (HDL-C) increased in all three groups compared with those before treatment (P < 0.05). The combination group had higher EF and SV than the decoction group and acupuncture group (P <0.05). There were no statistically significant differences in any indicators between the decoction group and the acupuncture group (P > 0.05). The comparison of the total incidence of adverse reactions among the three groups showed no statistically significant difference (P > 0.05).

Conclusion:

Buyang Huanwu Decoction combined with "Shao's Five-Needle Technique" is safe and effective in treating UA of coronary heart disease. It significantly improves angina symptoms and cardiac function, with notable lipid-regulating and anti-inflammatory effects.

Coronary heart disease  /  Unstable angina pectoris  /  Buyang Huanwu Decoction  /  Shao's five-needle technique
张乐, 赵磊, 张洁. 补阳还五汤联合“邵氏五针法”治疗冠心病不稳定型心绞痛的临床观察. 中医药学报, 2026 , 54 (6) : 90 -96 . DOI: 10.19664/j.cnki.1002-2392.260126
Le ZHANG, Lei ZHAO, Jie ZHANG. Clinical Observation of Buyang Huanwu Decoction Combined with "Shao's Five-Needle Technique" in Treating Unstable Angina Pectoris of Coronary Heart Disease[J]. Acta Chinese Medicine and Pharmacology, 2026 , 54 (6) : 90 -96 . DOI: 10.19664/j.cnki.1002-2392.260126
  • 陕西省科技计划项目(2017SF-277)
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2026年第54卷第6期
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doi: 10.19664/j.cnki.1002-2392.260126
  • 接收时间:2024-10-19
  • 首发时间:2026-09-17
  • 出版时间:2026-06-20
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  • 收稿日期:2024-10-19
  • 修回日期:2025-07-14
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陕西省科技计划项目(2017SF-277)
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    1.宝鸡市中医医院,陕西 宝鸡 721006
    2.河北医科大学第四医院,河北 石家庄 050011

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* 张洁(1990 -),女,硕士,主治医师,从事中医内科相关研究。
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2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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