Article(id=1307269528551969008, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1307269516371719010, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260124, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1740672000000, receivedDateStr=2025-02-28, revisedDate=1765123200000, revisedDateStr=2025-12-08, acceptedDate=null, acceptedDateStr=null, onlineDate=1789606943499, onlineDateStr=2026-09-17, pubDate=1781884800000, pubDateStr=2026-06-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789606943499, onlineIssueDateStr=2026-09-17, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789606943499, creator=13701087609, updateTime=1789606943499, updator=13701087609, issue=Issue{id=1307269516371719010, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='6', pageStart='1', pageEnd='126', issueExtLink='null', onlineDate='null', pubDate='1781884800000', pubDateStr='2026-06-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1789606940596, creator='13701087609', updateTime=1789606940596, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=80, endPage=84, ext={EN=ArticleExt(id=1307269529944477937, articleId=1307269528551969008, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Effect of Formula No.2 for Heart Failure Combined with Acupoint Application Therapy on Myocardial Enzyme Spectrum and Serum Levels of NT-proBNP and Troponin T in Patients with Chronic Heart Failure, columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To explore the influence of combination of Formula No.2 for Heart Failure and acupoint application on myocardial enzymes and serum N-terminal pro-brain natriuretic peptide (NT-pro-BNP) and cardiac troponin T (cTnT) in patients with chronic heart failure (CHF).
Methods: Totally 120 patients with chronic heart failure were randomized in the Taizhou hospital from Dec. 2021 to December Dec. 2024 were randomly grouped. 60 cases in the control group were treated with conventional western medicine, and the remaining 60 cases in the treatment group were given combined therapy with Formula No.2 for heart failure and acupoint application on this basis. The clinical efficacy and TCM symptoms scores and levels of serum myocardial enzymes [lactate dehydrogenase (LDH), creatine kinase (CK), CK-MB, AST], NT-pro-BNP and cTnT before and after treatment were compared between groups, and the adverse reactions in both groups were observed.
Results: The treatment group had higher total effective rate of treatment and lower scores of TCM symptoms after treatment compared to the control group (P < 0.05). The levels of LDH, CK, CK-MB, AST, NT-pro-BNP and cTnT in the treatment group were reduced after treatment compared with those in the control group (P < 0.05). No obvious differences were exhibited in the adverse reactions between both groups (P >0.05).
Conclusion: Formula No.2 for heart failure combined with acupoint application has a significant effect in the treatment of CHF, and it can effectively relieve the symptoms, and improve the myocardial enzymes and serum NT-pro-BNP and cTnT, without causing obvious adverse reactions.
, authors=Yumeng HOU, Jun CAO
*, Weiping WANG, authorsList=Yumeng HOU, Jun CAO, Weiping WANG, authorCompany=null, correspAuthors=Jun CAO, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1307269530296799474, articleId=1307269528551969008, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=心衰2号方与穴位贴敷结合治疗对慢性心力衰竭患者心肌酶谱及血清NT-proBNP、肌钙蛋白T水平的影响, columnId=1303760933084484510, journalTitle=中医药学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的： 探究心衰2号方与穴位贴敷结合治疗对慢性心力衰竭患者心肌酶谱及血清N-末端B型脑钠肽前体（NT-pro-BNP）、肌钙蛋白T（cTnT）水平的影响。
方法： 将2021年12月—2024年12月泰州市中医院收治的120例慢性心力衰竭患者随机分为对照组和试验组。对照组60例予以常规西药治疗，试验组60例在此基础上予以心衰2号方与穴位贴敷联合治疗。对比两组的临床疗效及中医证候积分，比较两组治疗前后的血清心肌酶谱、NT-pro-BNP、cTnT水平，观察两组的不良反应发生情况。
结果： 试验组的临床治疗总有效率高于对照组（P < 0.05），治疗后中医证候积分低于对照组（P < 0.05）；与对照组相比，治疗后试验组的乳酸脱氢酶（LDH）、肌酸激酶（CK）、肌酸激酶同工酶（CK-MB）、天冬氨酸氨基转移酶（AST）、NT-pro-BNP、cTnT水平均降低（P < 0.05）；两组间不良反应发生率比较差异无统计学意义（P > 0.05）。
结论： 心衰2号方与穴位贴敷结合治疗慢性心力衰竭效果明显，可有效缓解症状，改善心肌酶谱和血清NT-pro-BNP、cTnT水平，且未出现明显不良反应。
, authors=侯雨蒙, 曹军
*, 王卫平, authorsList=侯雨蒙, 曹军, 王卫平, authorCompany=null, correspAuthors=曹军, authorNote=
侯雨蒙（1990-），女，硕士，主治医师，从事中西医结合治疗心血管病相关研究。
, correspAuthorsNote=
* 曹军（1977-），男，硕士，主任医师，从事心血管内科相关研究工作。
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侯雨蒙（1990-），女，硕士，主治医师，从事中西医结合治疗心血管病相关研究。
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侯雨蒙（1990-），女，硕士，主治医师，从事中西医结合治疗心血管病相关研究。
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