Article(id=1307269523766277026, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1307269516371719010, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260116, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1740844800000, receivedDateStr=2025-03-02, revisedDate=1745164800000, revisedDateStr=2025-04-21, acceptedDate=null, acceptedDateStr=null, onlineDate=1789606942358, onlineDateStr=2026-09-17, pubDate=1781884800000, pubDateStr=2026-06-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789606942358, onlineIssueDateStr=2026-09-17, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789606942358, creator=13701087609, updateTime=1789606942358, updator=13701087609, issue=Issue{id=1307269516371719010, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='6', pageStart='1', pageEnd='126', issueExtLink='null', onlineDate='null', pubDate='1781884800000', pubDateStr='2026-06-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1789606940596, creator='13701087609', updateTime=1789606940596, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=39, endPage=42, ext={EN=ArticleExt(id=1307269525892789155, articleId=1307269523766277026, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Treatment of Insomnia from Kidney Deficiency-Related Mental Disorder with Polygala Based on the Therapeutic Principle of "Calm the Will of the Kidneys", columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=

"Insomnia due to the kidney's failure to store the will" is a sub-type of insomnia within the TCM "Five-Spirit" diagnostic classification system for insomnia, characterized by the direct symptom of waking early after falling asleep at night. Its disease location is in the kidney, and the pathogenesis is the failure of the kidney-will to rest peacefully. The therapeutic method of calming the kidney will can be adopted for treatment. The medicinal herb Yuanzhi (Radix Polygalae), first documented in the Shennong Bencao Jing (Shennong's Collection of Materia Medica), was said to have the function of "strengthening the will and doubling strength". Subsequent physicians through the ages have extensively discussed it, believing that Yuanzhi has the function of "calming the kidney will". The herb pairs Yuanzhi-Fuling (or Fushen), Yuanzhi-Shudihuang, Yuanzhi-Yizhiren, Yuanzhi-Suanzaoren, and the compound formulas Huanshao pill, Kongsheng Zhenzhong pill, and Qifu decoction can all calm the kidney will to treat insomnia due to the kidney's failure to store the will. Among the herb pairs, Yuanzhi-Fuling (or Fushen) and Yuanzhi-Suanzaoren calm the heart spirit and soothe the kidney will; Yuanzhi-Shudihuang enriches kidney essence and nourishes kidney water to calm the kidney will; Yuanzhi-Yizhiren boosts intelligence, stabilizes qi, and calms the kidney will. Among the compound formulas, Huanshao pill tonifies the spleen and kidney, stabilizes the will, and calms the spirit; Kongsheng Zhenzhong pill tonifies the kidney and heart, calming the spirit and stabilizing the will; Qifu decoction tonifies the kidney and benefits the marrow, stabilizing the will and nourishing the spirit. Modern research indicates that the mechanism of Yuanzhi in treating this type of insomnia is related to improving neuroinflammation, oxidative stress, and regulating neurotransmitters, which can provide references for clinical and mechanistic research on Yuanzhi for this condition.

, authors=Zhenhui LI1, Xingping ZHANG1, *, Xu CHEN1, Honglin JIA1, Zhengting LIANG2, Jinhong WU1, Yanling HU1, Guangke ZUO1, authorsList=Zhenhui LI, Xingping ZHANG, Xu CHEN, Honglin JIA, Zhengting LIANG, Jinhong WU, Yanling HU, Guangke ZUO, authorCompany=null, correspAuthors=Xingping ZHANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1307269526211556260, articleId=1307269523766277026, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=基于“安肾志”探讨远志治疗肾不藏志不寐, columnId=1303760928365892493, journalTitle=中医药学报, columnName=临证体会, runingTitle=null, highlight=null, articleAbstract=

肾不藏志不寐是中医不寐五神分型诊断法中以夜寐早寤为直接症状特征的不寐分型,其病位在肾,病机为肾志不安于舍,以安肾志为治法。远志一药,始载于《神农本草经》,称其可“强志倍力”,此后历代医家多有论述,认为远志有“安肾志”之功。其药对远志-茯苓(神)、远志-熟地黄、远志-益智仁、远志-炒酸枣仁及复方还少丹、孔圣枕中丹、七福饮均可安肾志以治疗肾不藏志不寐,药对中远志-茯苓(神)、远志-炒酸枣仁可宁心神、安肾志,远志-熟地黄补肾精、滋肾水以安肾志,远志-益智仁益智固气安肾志,复方中还少丹补脾益肾、定志安神,孔圣枕中丹补肾益心、安神定志,七福饮补肾益髓、定志养神。另外,现代研究表明远志治疗肾不藏志不寐的作用机制与改善神经炎症、缓解氧化应激及调节神经递质相关,可为远志治疗肾不藏志不寐的临床及机制研究提供参考。

, authors=李振辉1, 张星平1, *, 陈旭1, 贾宏林1, 梁政亭2, 吴金鸿1, 胡燕玲1, 左广珂1, authorsList=李振辉, 张星平, 陈旭, 贾宏林, 梁政亭, 吴金鸿, 胡燕玲, 左广珂, authorCompany=null, correspAuthors=张星平, authorNote=

李振辉(1998-),男,博士研究生,研究方向:中医内科不寐病、肾病的诊断与治疗。

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* 张星平(1961-),男,硕士,教授,博士生导师,研究方向:中医内科不寐病、肾病的诊断与治疗。
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李振辉(1998-),男,博士研究生,研究方向:中医内科不寐病、肾病的诊断与治疗。

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基于“安肾志”探讨远志治疗肾不藏志不寐
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李振辉 1 , 张星平 1, * , 陈旭 1 , 贾宏林 1 , 梁政亭 2 , 吴金鸿 1 , 胡燕玲 1 , 左广珂 1
中医药学报 | 临证体会 2026,54(6): 39-42
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中医药学报 |临证体会 2026 , 54 (6) : 39 -42
基于“安肾志”探讨远志治疗肾不藏志不寐
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830099)])])]
李振辉1, 张星平1, *, 陈旭1, 贾宏林1, 梁政亭2, 吴金鸿1, 胡燕玲1, 左广珂1
作者信息
  • 1.新疆医科大学第四临床医学院,新疆 乌鲁木齐 830099
  • 2.新疆医科大学,新疆 乌鲁木齐 830017
通讯作者:
* 张星平(1961-),男,硕士,教授,博士生导师,研究方向:中医内科不寐病、肾病的诊断与治疗。
作者简介:

李振辉(1998-),男,博士研究生,研究方向:中医内科不寐病、肾病的诊断与治疗。

Treatment of Insomnia from Kidney Deficiency-Related Mental Disorder with Polygala Based on the Therapeutic Principle of "Calm the Will of the Kidneys"
Zhenhui LI1, Xingping ZHANG1, *, Xu CHEN1, Honglin JIA1, Zhengting LIANG2, Jinhong WU1, Yanling HU1, Guangke ZUO1
Affiliations
  • 1.The Fourth Clinical Medical College of Xinjiang Medical University, Urumqi 830099, China
  • 2.Xinjiang Medical University, Urumqi 830017, China
出版时间: 2026-06-20 doi: 10.19664/j.cnki.1002-2392.260116
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肾不藏志不寐是中医不寐五神分型诊断法中以夜寐早寤为直接症状特征的不寐分型,其病位在肾,病机为肾志不安于舍,以安肾志为治法。远志一药,始载于《神农本草经》,称其可“强志倍力”,此后历代医家多有论述,认为远志有“安肾志”之功。其药对远志-茯苓(神)、远志-熟地黄、远志-益智仁、远志-炒酸枣仁及复方还少丹、孔圣枕中丹、七福饮均可安肾志以治疗肾不藏志不寐,药对中远志-茯苓(神)、远志-炒酸枣仁可宁心神、安肾志,远志-熟地黄补肾精、滋肾水以安肾志,远志-益智仁益智固气安肾志,复方中还少丹补脾益肾、定志安神,孔圣枕中丹补肾益心、安神定志,七福饮补肾益髓、定志养神。另外,现代研究表明远志治疗肾不藏志不寐的作用机制与改善神经炎症、缓解氧化应激及调节神经递质相关,可为远志治疗肾不藏志不寐的临床及机制研究提供参考。

中医不寐五神分型  /  远志  /  肾不藏志不寐  /  安肾志  /  论治

"Insomnia due to the kidney's failure to store the will" is a sub-type of insomnia within the TCM "Five-Spirit" diagnostic classification system for insomnia, characterized by the direct symptom of waking early after falling asleep at night. Its disease location is in the kidney, and the pathogenesis is the failure of the kidney-will to rest peacefully. The therapeutic method of calming the kidney will can be adopted for treatment. The medicinal herb Yuanzhi (Radix Polygalae), first documented in the Shennong Bencao Jing (Shennong's Collection of Materia Medica), was said to have the function of "strengthening the will and doubling strength". Subsequent physicians through the ages have extensively discussed it, believing that Yuanzhi has the function of "calming the kidney will". The herb pairs Yuanzhi-Fuling (or Fushen), Yuanzhi-Shudihuang, Yuanzhi-Yizhiren, Yuanzhi-Suanzaoren, and the compound formulas Huanshao pill, Kongsheng Zhenzhong pill, and Qifu decoction can all calm the kidney will to treat insomnia due to the kidney's failure to store the will. Among the herb pairs, Yuanzhi-Fuling (or Fushen) and Yuanzhi-Suanzaoren calm the heart spirit and soothe the kidney will; Yuanzhi-Shudihuang enriches kidney essence and nourishes kidney water to calm the kidney will; Yuanzhi-Yizhiren boosts intelligence, stabilizes qi, and calms the kidney will. Among the compound formulas, Huanshao pill tonifies the spleen and kidney, stabilizes the will, and calms the spirit; Kongsheng Zhenzhong pill tonifies the kidney and heart, calming the spirit and stabilizing the will; Qifu decoction tonifies the kidney and benefits the marrow, stabilizing the will and nourishing the spirit. Modern research indicates that the mechanism of Yuanzhi in treating this type of insomnia is related to improving neuroinflammation, oxidative stress, and regulating neurotransmitters, which can provide references for clinical and mechanistic research on Yuanzhi for this condition.

TCM insomnia with five-spirit pattern differentiation  /  Yuanzhi (Polygala)  /  Insomnia due to kidney's failure to store the will  /  Calming the kidney spirit  /  Treatment based on syndrome differentiation
李振辉, 张星平, 陈旭, 贾宏林, 梁政亭, 吴金鸿, 胡燕玲, 左广珂. 基于“安肾志”探讨远志治疗肾不藏志不寐. 中医药学报, 2026 , 54 (6) : 39 -42 . DOI: 10.19664/j.cnki.1002-2392.260116
Zhenhui LI, Xingping ZHANG, Xu CHEN, Honglin JIA, Zhengting LIANG, Jinhong WU, Yanling HU, Guangke ZUO. Treatment of Insomnia from Kidney Deficiency-Related Mental Disorder with Polygala Based on the Therapeutic Principle of "Calm the Will of the Kidneys"[J]. Acta Chinese Medicine and Pharmacology, 2026 , 54 (6) : 39 -42 . DOI: 10.19664/j.cnki.1002-2392.260116
  • 国家中医药管理局“十四五”高水平中医药重点学科建设项目(国中医药人教函〔2023〕85号)
  • 国家自然科学基金项目(82160873; 81960837; 81560762; 81260526)
  • 新疆自然科学基金重点项目(2022D01D48)
  • 全国名老中医药专家传承工作室(国中医药人教函〔2022〕75号)
  • 新疆“天池英才”计划青年博士项目
  • 新疆研究生科研创新项目(XJ2026G161)
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2026年第54卷第6期
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doi: 10.19664/j.cnki.1002-2392.260116
  • 接收时间:2025-03-02
  • 首发时间:2026-09-17
  • 出版时间:2026-06-20
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  • 收稿日期:2025-03-02
  • 修回日期:2025-04-21
基金
国家中医药管理局“十四五”高水平中医药重点学科建设项目(国中医药人教函〔2023〕85号)
国家自然科学基金项目(82160873; 81960837; 81560762; 81260526)
新疆自然科学基金重点项目(2022D01D48)
全国名老中医药专家传承工作室(国中医药人教函〔2022〕75号)
新疆“天池英才”计划青年博士项目
新疆研究生科研创新项目(XJ2026G161)
作者信息
    1.新疆医科大学第四临床医学院,新疆 乌鲁木齐 830099
    2.新疆医科大学,新疆 乌鲁木齐 830017

通讯作者:

* 张星平(1961-),男,硕士,教授,博士生导师,研究方向:中医内科不寐病、肾病的诊断与治疗。
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2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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