Article(id=1307269612287062292, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1307269601637724372, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260100, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1747065600000, receivedDateStr=2025-05-13, revisedDate=1768320000000, revisedDateStr=2026-01-14, acceptedDate=null, acceptedDateStr=null, onlineDate=1789606963464, onlineDateStr=2026-09-17, pubDate=1779206400000, pubDateStr=2026-05-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789606963464, onlineIssueDateStr=2026-09-17, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789606963464, creator=13701087609, updateTime=1789606963464, updator=13701087609, issue=Issue{id=1307269601637724372, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='5', pageStart='1', pageEnd='126', issueExtLink='null', onlineDate='null', pubDate='1779206400000', pubDateStr='2026-05-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1789606960925, creator='13701087609', updateTime=1789606960925, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=73, endPage=76, ext={EN=ArticleExt(id=1307269612454834453, articleId=1307269612287062292, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Effects of Modified Sangbaipi Decoction on Therapeutic Efficacy and Pulmonary Function in Patients with Acute Exacerbation of COPD (Phlegm-Heat Obstructing Lung Syndrome), columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To investigate the efficacy of modified Sangbaipi Decoction on patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) and its effect on pulmonary function.
Methods: A total of 120 patients with acute exacerbation of COPD admitted to Shunyi Hospital, Beijing Traditional Chinese Medicine Hospital, from June 2023 to June 2025 were selected and randomly divided into a control group (conventional Western medicine treatment) and an observation group (conventional Western medicine + modified Sangbaipi Decoction treatment) with 60 cases each. Observed and compared the TCM Syndrome Score, clinical efficacy, pulmonary function indices, inflammatory factors and the incidence of adverse reactions in both groups.
Results: The total effectiveness rate of the observation group after treatment were higher than that of the control group (P < 0.05) ; The TCM syndrome score subjects group was lower than that of the control group (P <0.05). After treatment, the levels of FEV1, FVC and FEV1/FVC in both groups were increased and the levels of IL-6, CRP and PCT were decreased (P < 0.05), and the observation group was lower than that of the control group (P < 0.05). There was no apparent difference in the incidence of adverse reactions between both groups (P > 0.05).
Conclusion: Modified Sangbaipi Decoction has significant efficacy in patients with acute exacerbation of COPD (Phlegm-heat obstructing lung syndrome), can effectively improve the clinical symptoms and pulmonary function indices, reduce the level of inflammatory factors, and it has a high degree of safety.
, authors=Haiyue ZHONG, Ning ZHANG, Jingshuai FENG, Dayong XIN
*, authorsList=Haiyue ZHONG, Ning ZHANG, Jingshuai FENG, Dayong XIN, authorCompany=null, correspAuthors=Dayong XIN, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1307269612819738902, articleId=1307269612287062292, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=桑白皮汤加味对COPD急性加重期
(痰热壅肺证
)患者疗效及肺功能影响, columnId=1303760933084484510, journalTitle=中医药学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的： 探讨桑白皮汤加味对慢性阻塞性肺疾病（COPD）急性加重期患者的疗效及对肺功能的影响。
方法： 选取2022年10月—2024年10月北京中医医院顺义医院收治的120例COPD急性加重期患者，随机数字表法分为对照组（常规西医治疗）和观察组（常规西医+桑白皮汤加味治疗），各60例。观察并比较两组患者的中医证候积分、临床疗效、肺功能指标、炎性因子及不良反应发生情况。
结果： 治疗后观察组总有效率高于对照组（P < 0.05）；观察组患者中医证候积分低于对照组（P < 0.05）。治疗后，两组FEV1、FVC及FEV1/FVC水平均较治疗前提高（P < 0.05），白介素-6（IL-6）、C反应蛋白及降钙素原水平均降低（P < 0.05），且观察组低于对照组（P < 0.05）。两组患者不良反应发生率无明显差异（P > 0.05）。
结论： 桑白皮汤加味对COPD急性加重期（痰热壅肺证）患者具有显著疗效，能有效改善患者症状及肺功能，降低炎症因子水平，且安全性较高。
, authors=仲海悦, 张宁, 冯京帅, 辛大永
*, authorsList=仲海悦, 张宁, 冯京帅, 辛大永, authorCompany=null, correspAuthors=辛大永, authorNote=
仲海悦（1987-），女，硕士，住院医师，从事呼吸系统疾病临床研究。
, correspAuthorsNote=
* 辛大永（1973-），男，硕士，主任医师，从事慢性气道病变的中医临床研究。
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仲海悦（1987-），女，硕士，住院医师，从事呼吸系统疾病临床研究。
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