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They were randomly divided into a control group (n = 62, conventional postoperative anti - infection therapy) and an observation group (n =62, XTD combined with conventional therapy). All patients underwent hysteroscopic - laparoscopic surgery, followed by 3 menstrual cycles of treatment. Ovarian function (LH, E2 , FSH, AMH), endometrial receptivity(endometrial thickness, volume, PI, RI), TCM syndrome scores, postoperative complications, pregnancy outcomes, and hydrosalpinx recurrence were assessed during a 1 - year follow - up.Results: Compared with the control group, the observation group showed higher LH, FSH, and AMH levels, lower E2 and TCM syndrome scores, improved endometrial receptivity, higher intrauterine pregnancy rate (P < 0.05), and lower hydrosalpinx recurrence rate (P < 0.05). No significant difference in safety was observed between groups (P > 0.05).Conclusion: XTD combined with hysteroscopic- laparoscopic surgery significantly improves ovarian function, enhances endometrial receptivity, increases intrauterine pregnancy rates, and reduces hydrosalpinx recurrence in patients with hydrosalpinx - related infertility (dampness - heat and blood stasis syndrome) , with a favorable safety profile., authors=JIANG Haiying1 , LIN Xiaohua2 , authorsList=JIANG Haiying, LIN Xiaohua, authorCompany=1 Hebei University of Chinese Medicine, Shijiazhuang 050091, China; 2 The First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang 050011, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1303760946422379067, articleId=1303760946208469562, tenantId=1146029695717560320, journalId=1302318977290174537, language=CN, title=行水通歧方辅助治疗输卵管积水性不孕临床疗效观察, columnId=1303760933084484510, journalTitle=中医药学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=目的: 探讨行水通歧方对输卵管积水性不孕患者的临床疗效。方法: 选择2023年1月—2024年1月在河北中医药大学第一附属医院接受治疗的输卵管积水性不孕患者为研究对象,中医诊断为湿热瘀阻型不孕,共124例。通过随机数字表法将所有患者分为对照组与观察组,每组62例。两组患者均接受宫腹腔镜微创手术治疗,对照组术后接受常规抗感染治疗,观察组在对照组的基础上服用行水通歧方,连续治疗3个月经周期后评估治疗效果。比较两组患者治疗前后的卵巢功能指标[黄体生成激素(LH)、雌二醇(E2 )、卵泡刺激素(FSH)、抗苗勒氏管激素(AMH)]、子宫内膜容受性、中医证候积分,并记录术后并发症情况。对所有患者进行为期1年的随访,记录妊娠结局和积水复发情况。结果: 观察组治疗后LH、FSH、AMH水平高于对照组(P < 0.05),E2 和中医证候积分低于对照组(P < 0.05),且观察组治疗后的子宫内膜容受性改善优于对照组(P < 0.05),宫内妊娠率高于对照组(P < 0.01),积水复发率低于对照组,差异均有统计学意义(P < 0.01)。两组患者术后安全性相当,差异无统计学意义(P > 0.05)。结论: 行水通歧方联合宫腹腔镜手术可改善湿热瘀阻型输卵管积水性不孕患者的卵巢功能,提高宫内妊娠率并降低积水复发率。, 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中医药学报
|临床研究
2026
, 54
(3) :
107
-111
行水通歧方辅助治疗输卵管积水性不孕临床疗效观察
全屏
姜海莹1 , 林晓华2
作者信息
1. 河北中医药大学,河北 石家庄 050091; 2. 河北中医药大学第一附属医院,河北 石家庄 050011
通讯作者:
* 林晓华(1979-),女,博士,主任医师,研究方向:中医药治疗妇科内分泌疾病。
作者简介:
姜海莹(1986-),女,主治医师,研究方向:中医妇科学。
Clinical Observation on the Efficacy of Xingshui Tongqi Decoction as Adjuvant Therapy for Hydrosalpinx - induced Infertility
JIANG Haiying1 , LIN Xiaohua2
Affiliations
1 Hebei University of Chinese Medicine, Shijiazhuang 050091, China; 2 The First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang 050011, China
doi: 10.19664/j.cnki.1002-2392.260065
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目的: 探讨行水通歧方对输卵管积水性不孕患者的临床疗效。方法: 选择2023年1月—2024年1月在河北中医药大学第一附属医院接受治疗的输卵管积水性不孕患者为研究对象,中医诊断为湿热瘀阻型不孕,共124例。通过随机数字表法将所有患者分为对照组与观察组,每组62例。两组患者均接受宫腹腔镜微创手术治疗,对照组术后接受常规抗感染治疗,观察组在对照组的基础上服用行水通歧方,连续治疗3个月经周期后评估治疗效果。比较两组患者治疗前后的卵巢功能指标[黄体生成激素(LH)、雌二醇(E2 )、卵泡刺激素(FSH)、抗苗勒氏管激素(AMH)]、子宫内膜容受性、中医证候积分,并记录术后并发症情况。对所有患者进行为期1年的随访,记录妊娠结局和积水复发情况。结果: 观察组治疗后LH、FSH、AMH水平高于对照组(P < 0.05),E2 和中医证候积分低于对照组(P < 0.05),且观察组治疗后的子宫内膜容受性改善优于对照组(P < 0.05),宫内妊娠率高于对照组(P < 0.01),积水复发率低于对照组,差异均有统计学意义(P < 0.01)。两组患者术后安全性相当,差异无统计学意义(P > 0.05)。结论: 行水通歧方联合宫腹腔镜手术可改善湿热瘀阻型输卵管积水性不孕患者的卵巢功能,提高宫内妊娠率并降低积水复发率。
行水通歧方
/
湿热瘀阻
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输卵管积水性不孕
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子宫内膜容受性
Objective: To evaluate the therapeutic effect of ""Xingshui Tongqi Decoction"" (XTD) in patients with hydrosalpinx - related infertility of dampness - heat and blood stasis syndrome.Methods: A total of 124 patients diagnosed with hydrosalpinx - related infertility (dampness - heat and blood stasis syndrome) and treated in the First Affiliated Hospital of Hebei University of Chinese Medicine from January 2023 to January 2024 were enrolled. They were randomly divided into a control group (n = 62, conventional postoperative anti - infection therapy) and an observation group (n =62, XTD combined with conventional therapy). All patients underwent hysteroscopic - laparoscopic surgery, followed by 3 menstrual cycles of treatment. Ovarian function (LH, E2 , FSH, AMH), endometrial receptivity(endometrial thickness, volume, PI, RI), TCM syndrome scores, postoperative complications, pregnancy outcomes, and hydrosalpinx recurrence were assessed during a 1 - year follow - up.Results: Compared with the control group, the observation group showed higher LH, FSH, and AMH levels, lower E2 and TCM syndrome scores, improved endometrial receptivity, higher intrauterine pregnancy rate (P < 0.05), and lower hydrosalpinx recurrence rate (P < 0.05). No significant difference in safety was observed between groups (P > 0.05).Conclusion: XTD combined with hysteroscopic- laparoscopic surgery significantly improves ovarian function, enhances endometrial receptivity, increases intrauterine pregnancy rates, and reduces hydrosalpinx recurrence in patients with hydrosalpinx - related infertility (dampness - heat and blood stasis syndrome) , with a favorable safety profile.
Xingshui Tongqi Decoction
/
Dampness - heat and blood stasis syndrome
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Hydrosalpinx - related infertility
/
Endometrial receptivity
姜海莹, 林晓华.
行水通歧方辅助治疗输卵管积水性不孕临床疗效观察.
中医药学报,
2026
, 54
(3)
: 107
-111
.
DOI: 10.19664/j.cnki.1002-2392.260065
JIANG Haiying, LIN Xiaohua.
Clinical Observation on the Efficacy of Xingshui Tongqi Decoction as Adjuvant Therapy for Hydrosalpinx - induced Infertility[J].
Acta Chinese Medicine and Pharmacology ,
2026
, 54
(3)
: 107
-111
.
DOI: 10.19664/j.cnki.1002-2392.260065
2026年第54卷第3期
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doi: 10.19664/j.cnki.1002-2392.260065
接收时间:2025-04-21
首发时间:2026-09-07
https://castjournals.cast.org.cn/joweb/zyyxb/CN/10.19664/j.cnki.1002-2392.260065
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2种不同金属材料的力学参数
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