Article(id=1304438802416685069, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1304438786377674789, articleNumber=null, orderNo=null, doi=10.19664/j.cnki.1002-2392.260012, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1732550400000, receivedDateStr=2024-11-26, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1788932045796, onlineDateStr=2026-09-09, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1788932045796, onlineIssueDateStr=2026-09-09, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1788932045796, creator=13701087609, updateTime=1788932045796, updator=13701087609, issue=Issue{id=1304438786377674789, tenantId=1146029695717560320, journalId=1302318977290174537, year='2026', volume='54', issue='1', pageStart='1', pageEnd='128', issueExtLink='null', onlineDate='null', pubDate='1768838400000', pubDateStr='2026-01-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1788932041973, creator='13701087609', updateTime=1788934739716, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1304450101590651052, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1304438786377674789, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1304450101590651053, tenantId=1146029695717560320, journalId=1302318977290174537, issueId=1304438786377674789, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=62, endPage=66, ext={EN=ArticleExt(id=1304438804245401615, articleId=1304438802416685069, tenantId=1146029695717560320, journalId=1302318977290174537, language=EN, title=Effect Analysis of Spleen - Strengthening, Dampness - Eliminating and Turbidity - Resolving Formula in Treating Patients with Spleen Deficiency and Damp - Phlegm Type Polycystic Ovary Syndrome Complicated by Insulin Resistance, columnId=null, journalTitle=Acta Chinese Medicine and Pharmacology, columnName=null, runingTitle=null, highlight=null, articleAbstract=Objective: To investigate the therapeutic effect of the Spleen - strengthening, Dampness - eliminating, and Turbidity - resolving Formula on patients with Spleen deficiency and damp - phlegm type polycystic ovary syndrome(PCOS) complicated by insulin resistance (IR).Methods: A total of 104 patients diagnosed with Spleen deficiency and damp - phlegm type PCOS complicated by IR were selected from Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine between April 2021 and April 2024. They were randomly assigned to the control group (n = 52, conventional treatment) and the Traditional Chinese Medicine (TCM) group (n = 52, receiving Spleen - strengthening, Dampness - eliminating and Turbidity - resolving Formula in addition to the control group treatment). Hormonal indicators, glucose and lipid metabolism indicators, TCM syndrome scores, imaging indicators, and the incidence of adverse reactions were compared before and after treatment.Results: After treatment, the FSH level in the TCM group was higher than that in the control group, while the levels of LH, AMH, LH/FSH, FPG, FINS, and HOMA - IR were lower (P < 0.05). The TCM group also showed lower scores for symptoms such as loose stools, diarrhea, loss of appetite, and fatigue compared to the control group (P < 0.05). Additionally, the ovarian volume and number of follicles in the TCM group were lower, while the endometrial thickness was higher than those in the control group (P <0.05). The incidence of adverse events in the TCM group did not differ statistically from that in the control group (P >0.05).Conclusion: The spleen - strengthening, dampness - eliminating, and turbidity - resolving formula can significantly improve metabolic status and enhance insulin sensitivity in patients with spleen - deficiency and phlegm- dampness type PCOS combined with IR. It is safe and holds great potential for broad clinical application and precision medicine., authors=SONG Weiwei1 , GUO Zhili1 , YU Ze1 , ZHOU Huihui2 , LIU Haiyan1 , authorsList=SONG Weiwei, GUO Zhili, YU Ze, ZHOU Huihui, LIU Haiyan, authorCompany=1 Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Cangzhou 061013, China; 目的： 探讨健脾祛湿化浊方对脾虚痰湿型多囊卵巢综合征（PCOS）合并胰岛素抵抗（IR）患者的治疗效果。 方法： 选取沧州中西医结合医院2021年4月—2024年4月接收的104例脾虚痰湿型PCOS合并IR患者作为研究对象，通过随机数字表法分为参照组（52例，常规治疗）和中医组（52例，参照组基础上加用健脾祛湿化浊方治疗）。比较两组患者治疗前后的激素指标、糖脂代谢指标、中医症状积分、影像学指标以及不良反应发生率。 结果： 治疗后中医组患者的FSH水平高于参照组（P < 0.05），LH、AMH、LH/FSH、FPG、FINS、HOMA - IR水平低于参照组（P < 0.05）。治疗后中医组患者的便溏、腹泻、食欲不振及疲乏中医症状积分均低于参照组（P < 0.05）。治疗后中医组患者的卵巢体积、卵泡数目均低于参照组（P < 0.05），子宫内膜厚度高于参照组（P < 0.05）。中医组的不良事件发生率与参照组比较差异无统计学意义（P > 0.05）。 结论： 健脾祛湿化浊方显著改善脾虚痰湿型PCOS合并IR患者的代谢状态，提升胰岛素敏感性。, authors=宋伟伟1 , 郭志莉1 , 于泽1 , 周慧慧2 , 刘海燕1 , authorsList=宋伟伟, 郭志莉, 于泽, 周慧慧, 刘海燕, authorCompany=1 河北省沧州中西医结合医院，河北 沧州 061013;
中医药学报
|临床研究
2026
, 54
(1) :
62
-66
健脾祛湿化浊方治疗脾虚痰湿型多囊卵巢综合征合并胰岛素抵抗患者的效果分析
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宋伟伟1 , 郭志莉1 , 于泽1 , 周慧慧2 , 刘海燕1
作者信息
1 河北省沧州中西医结合医院，河北 沧州 061013;
作者简介:
宋伟伟（1990-），女，硕士，主治医师，从事女性生殖内分泌相关研究。
Effect Analysis of Spleen - Strengthening, Dampness - Eliminating and Turbidity - Resolving Formula in Treating Patients with Spleen Deficiency and Damp - Phlegm Type Polycystic Ovary Syndrome Complicated by Insulin Resistance
SONG Weiwei1 , GUO Zhili1 , YU Ze1 , ZHOU Huihui2 , LIU Haiyan1
Affiliations
1 Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Cangzhou 061013, China;
doi: 10.19664/j.cnki.1002-2392.260012
文章导航
目的： 探讨健脾祛湿化浊方对脾虚痰湿型多囊卵巢综合征（PCOS）合并胰岛素抵抗（IR）患者的治疗效果。 方法： 选取沧州中西医结合医院2021年4月—2024年4月接收的104例脾虚痰湿型PCOS合并IR患者作为研究对象，通过随机数字表法分为参照组（52例，常规治疗）和中医组（52例，参照组基础上加用健脾祛湿化浊方治疗）。比较两组患者治疗前后的激素指标、糖脂代谢指标、中医症状积分、影像学指标以及不良反应发生率。 结果： 治疗后中医组患者的FSH水平高于参照组（P < 0.05），LH、AMH、LH/FSH、FPG、FINS、HOMA - IR水平低于参照组（P < 0.05）。治疗后中医组患者的便溏、腹泻、食欲不振及疲乏中医症状积分均低于参照组（P < 0.05）。治疗后中医组患者的卵巢体积、卵泡数目均低于参照组（P < 0.05），子宫内膜厚度高于参照组（P < 0.05）。中医组的不良事件发生率与参照组比较差异无统计学意义（P > 0.05）。 结论： 健脾祛湿化浊方显著改善脾虚痰湿型PCOS合并IR患者的代谢状态，提升胰岛素敏感性。
多囊卵巢综合征
/
脾虚痰湿
/
健脾祛湿化浊方
/
胰岛素抵抗
Objective: To investigate the therapeutic effect of the Spleen - strengthening, Dampness - eliminating, and Turbidity - resolving Formula on patients with Spleen deficiency and damp - phlegm type polycystic ovary syndrome(PCOS) complicated by insulin resistance (IR).Methods: A total of 104 patients diagnosed with Spleen deficiency and damp - phlegm type PCOS complicated by IR were selected from Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine between April 2021 and April 2024. They were randomly assigned to the control group (n = 52, conventional treatment) and the Traditional Chinese Medicine (TCM) group (n = 52, receiving Spleen - strengthening, Dampness - eliminating and Turbidity - resolving Formula in addition to the control group treatment). Hormonal indicators, glucose and lipid metabolism indicators, TCM syndrome scores, imaging indicators, and the incidence of adverse reactions were compared before and after treatment.Results: After treatment, the FSH level in the TCM group was higher than that in the control group, while the levels of LH, AMH, LH/FSH, FPG, FINS, and HOMA - IR were lower (P < 0.05). The TCM group also showed lower scores for symptoms such as loose stools, diarrhea, loss of appetite, and fatigue compared to the control group (P < 0.05). Additionally, the ovarian volume and number of follicles in the TCM group were lower, while the endometrial thickness was higher than those in the control group (P <0.05). The incidence of adverse events in the TCM group did not differ statistically from that in the control group (P >0.05).Conclusion: The spleen - strengthening, dampness - eliminating, and turbidity - resolving formula can significantly improve metabolic status and enhance insulin sensitivity in patients with spleen - deficiency and phlegm- dampness type PCOS combined with IR. It is safe and holds great potential for broad clinical application and precision medicine.
Polycystic ovary syndrome
/
Spleen deficiency and damp - phlegm
/
Spleen - strengthening, Dampness- eliminating and Turbidity - resolving Formula
/
Insulin resistance
宋伟伟, 郭志莉, 于泽, 周慧慧, 刘海燕.
健脾祛湿化浊方治疗脾虚痰湿型多囊卵巢综合征合并胰岛素抵抗患者的效果分析.
中医药学报,
2026
, 54
(1)
: 62
-66
.
DOI: 10.19664/j.cnki.1002-2392.260012
SONG Weiwei, GUO Zhili, YU Ze, ZHOU Huihui, LIU Haiyan.
Effect Analysis of Spleen - Strengthening, Dampness - Eliminating and Turbidity - Resolving Formula in Treating Patients with Spleen Deficiency and Damp - Phlegm Type Polycystic Ovary Syndrome Complicated by Insulin Resistance[J].
Acta Chinese Medicine and Pharmacology ,
2026
, 54
(1)
: 62
-66
.
DOI: 10.19664/j.cnki.1002-2392.260012
2026年第54卷第1期
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doi: 10.19664/j.cnki.1002-2392.260012
接收时间：2024-11-26
首发时间：2026-09-09
https://castjournals.cast.org.cn/joweb/zyyxb/CN/10.19664/j.cnki.1002-2392.260012
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2种不同金属材料的力学参数
科 属数 种数 占总种数比例 属 种数 占总种数比例 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
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