Article(id=1319955805596660499, tenantId=1146029695717560320, journalId=1315121837170065538, issueId=1319955707420586876, articleNumber=PA20260409_1leEcCRO, orderNo=null, doi=10.16368/j.issn.1674-8999.2026.01.024, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792631587647, onlineDateStr=2026-10-22, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792631587646, onlineIssueDateStr=2026-10-22, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792631587646, creator=admin, updateTime=1792631587646, updator=admin, issue=Issue{id=1319955707420586876, tenantId=1146029695717560320, journalId=1315121837170065538, year='2026', volume='41', issue='1', pageStart='1', pageEnd='141', issueExtLink='null', onlineDate='null', pubDate='1767974400000', pubDateStr='2026-01-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=0, articleOrder=1, issueType=1, specialIssue=null, createTime=1792631564240, creator='ztmeta', updateTime=1792997687704, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1321491340635001527, tenantId=1146029695717560320, journalId=1315121837170065538, issueId=1319955707420586876, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1321491340635001528, tenantId=1146029695717560320, journalId=1315121837170065538, issueId=1319955707420586876, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=152, endPage=163, ext={CN=ArticleExt(id=1319955805995119380, articleId=1319955805596660499, tenantId=1146029695717560320, journalId=1315121837170065538, language=CN, title=基于4D-DIA蛋白质组学探讨散偏汤治疗急性偏头痛的作用机制, columnId=null, journalTitle=中医学报, columnName=实验研究, runingTitle=null, highlight=null, articleAbstract=目的:基于4D-DIA蛋白质组学技术，探索散偏汤干预偏头痛模型大鼠的潜在作用机制。方法:将18只雄性SD大鼠随机分为3组:空白组（C组）、模型组（EM组）、散偏汤组（SPT组），每组6只。C组皮下注射生理盐水，EM组与SPT组皮下注射硝酸甘油(10 mg·kg⁻¹)制备偏头痛模型。SPT组予散偏汤(9.1 mg·kg⁻¹)灌胃，C组与EM组给予等体积超纯水灌胃，连续7 d。取各组大鼠三叉神经节进行4D数据非依赖采集（four-dimensional data-independent acquisition,4D-DIA）蛋白质组学测序，筛选差异表达蛋白，并进行基因本体论（Gene Ontology,GO）与京都基因与基因组百科全书（Kyoto Encyclopedia of Genes and Genomes,KEGG）富集分析。结果:C组、EM组、SPT组分别鉴定出9 127、9 151、9 238种蛋白质。C组与EM组间鉴定出183种差异表达蛋白; EM组与SPT组间鉴定出123种差异表达蛋白（上调53种，下调70种）。GO与KEGG富集分析显示，差异表达蛋白主要富集在炎性反应、糖代谢、免疫应答、性激素调节等生物过程，涉及瞬时感受器电位通道（transient receptor potential,TRP）、促性腺激素释放激素（gonadotropin-releasing hormone,GnRH）分泌、Ⅰ型糖尿病等相关通路。结论:散偏汤可能通过调节炎性反应、糖代谢、免疫应答及性激素水平，并干预TRP通道、GnRH分泌及Ⅰ型糖尿病等相关通路，从而发挥治疗偏头痛的作用。, authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null)}, authors=[Author(id=1319955808209711897, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=王依琳, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=["cuiyinglin-vip@163.com"], emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955808511701788, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, authorId=1319955808209711897, language=CN, stringName=王依琳, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,², address=^1.河南中医药大学第二临床医学院,^2.河南中医药大学第二附属医院/河南省中医院河南中医药大学第二临床医学院, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955807718978325, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, xref=1, ext=[AuthorCompanyExt(id=1319955807727366934, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, companyId=1319955807718978325, language=CN, country=null, province=null, city=null, postcode=null, companyName=河南中医药大学第二临床医学院, departmentName=null, remark=^1.河南中医药大学第二临床医学院)]), AuthorCompany(id=1319955808088077079, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, xref=2, ext=[AuthorCompanyExt(id=1319955808096465688, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, companyId=1319955808088077079, language=CN, country=null, province=null, city=null, postcode=null, companyName=河南中医药大学第二附属医院/河南省中医院, departmentName=null, remark=^2.河南中医药大学第二附属医院/河南省中医院)])]), Author(id=1319955808574616349, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=贾菁楠, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955808650113824, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, authorId=1319955808574616349, language=CN, stringName=贾菁楠, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,², address=^1.河南中医药大学第二临床医学院,^2.河南中医药大学第二附属医院/河南省中医院河南中医药大学第二临床医学院, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955807718978325, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, xref=1, ext=[AuthorCompanyExt(id=1319955807727366934, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, companyId=1319955807718978325, language=CN, country=null, province=null, city=null, postcode=null, companyName=河南中医药大学第二临床医学院, departmentName=null, remark=^1.河南中医药大学第二临床医学院)]), AuthorCompany(id=1319955808088077079, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, xref=2, ext=[AuthorCompanyExt(id=1319955808096465688, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, companyId=1319955808088077079, language=CN, country=null, province=null, city=null, postcode=null, companyName=河南中医药大学第二附属医院/河南省中医院, departmentName=null, remark=^2.河南中医药大学第二附属医院/河南省中医院)])]), Author(id=1319955808733999905, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=韩赵成, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955809010823972, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, authorId=1319955808733999905, language=CN, stringName=韩赵成, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,², address=^1.河南中医药大学第二临床医学院,^2.河南中医药大学第二附属医院/河南省中医院河南中医药大学第二临床医学院, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955807718978325, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, xref=1, ext=[AuthorCompanyExt(id=1319955807727366934, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, companyId=1319955807718978325, language=CN, country=null, province=null, city=null, postcode=null, companyName=河南中医药大学第二临床医学院, departmentName=null, remark=^1.河南中医药大学第二临床医学院)]), AuthorCompany(id=1319955808088077079, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, xref=2, ext=[AuthorCompanyExt(id=1319955808096465688, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, companyId=1319955808088077079, language=CN, country=null, province=null, city=null, postcode=null, companyName=河南中医药大学第二附属医院/河南省中医院, departmentName=null, remark=^2.河南中医药大学第二附属医院/河南省中医院)])]), Author(id=1319955809354756901, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=崔应麟, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955809434448680, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, authorId=1319955809354756901, language=CN, stringName=崔应麟, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,², address=^1.河南中医药大学第二临床医学院,^2.河南中医药大学第二附属医院/河南省中医院河南中医药大学第二临床医学院, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955807718978325, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, xref=1, ext=[AuthorCompanyExt(id=1319955807727366934, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, companyId=1319955807718978325, language=CN, country=null, province=null, city=null, postcode=null, companyName=河南中医药大学第二临床医学院, departmentName=null, remark=^1.河南中医药大学第二临床医学院)]), AuthorCompany(id=1319955808088077079, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, xref=2, ext=[AuthorCompanyExt(id=1319955808096465688, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, companyId=1319955808088077079, language=CN, country=null, province=null, city=null, postcode=null, companyName=河南中医药大学第二附属医院/河南省中医院, departmentName=null, remark=^2.河南中医药大学第二附属医院/河南省中医院)])])], keywords=[Keyword(id=1319955809547694889, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, language=CN, orderNo=1, keyword=急性偏头痛), Keyword(id=1319955809648358186, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, language=CN, orderNo=2, keyword=散偏汤), Keyword(id=1319955809807741739, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, language=CN, orderNo=3, keyword=4D-DIA蛋白质组学)], refs=[Reference(id=1319955810470441774, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[1], rfOrder=0, authorNames=null, journalName=null, refType=null, unstructuredReference=贾国香,董亚倩,杨娜,钱文秀,殷宏庆,杨珅珅,李遇伯.蛋白质组学策略助力中药现代化的研究进展[J].天津中医药大学学报,2021(03)., articleTitle=null, refAbstract=null), Reference(id=1319955810470441775, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[2], rfOrder=1, authorNames=null, journalName=null, refType=null, unstructuredReference=刘燕,赵永烈,李春胜,刘金民.散偏汤治疗偏头痛文献的Meta分析[J].中国中医急症,2019(02)., articleTitle=null, refAbstract=null), Reference(id=1319955810470441776, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[3], rfOrder=2, authorNames=null, journalName=null, refType=null, unstructuredReference=王榕,宋汉琳,徐福.加味丹栀逍遥散联合疏肝调神针法对偏头痛伴抑郁焦虑障碍认知功能及预后的影响[J].中华中医药学刊,2024(06)., articleTitle=null, refAbstract=null), Reference(id=1319955810470441777, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[4], rfOrder=3, authorNames=null, journalName=null, refType=null, unstructuredReference=付勇,廖璐,李琳慧,喻文,黄彪,胡凯玲,颜纯钏,熊俊,刘慧,章海凤.针药结合对无先兆性偏头痛患者临床症状及睡眠质量的影响[J].中华中医药杂志,2023(06)., articleTitle=null, refAbstract=null), Reference(id=1319955810470441778, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[5], rfOrder=4, authorNames=null, journalName=null, refType=null, unstructuredReference=赵永烈,王玉来,高颖,岳利锋.蛋白质组学在偏头痛(头风)研究中应用的探讨[J].辽宁中医药大学学报,2010(09)., articleTitle=null, refAbstract=null), Reference(id=1319955810470441779, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[6], rfOrder=5, authorNames=null, journalName=null, refType=null, unstructuredReference=中国医师协会神经内科医师分会,中国研究型医院学会头痛与感觉障碍专业委员会.中国偏头痛诊治指南（2022版）[J].中国疼痛医学杂志,2022(12)., articleTitle=null, refAbstract=null), Reference(id=1319955810470441780, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[7], rfOrder=6, authorNames=null, journalName=null, refType=null, unstructuredReference=辛萍,匡海学,李晓亮,王宇,张本梅,布赫,王知斌,孟永海,王艳宏,王秋红.蛋白质组学技术及其在中药作用机制研究中的应用[J].中国中药杂志,2018(05)., articleTitle=null, refAbstract=null), Reference(id=1319955810470441781, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[8], rfOrder=7, authorNames=null, journalName=null, refType=null, unstructuredReference=周盼盼,崔应麟,陈慧亭,朱燕.崔应麟治疗偏头痛的临床经验[J].中医药通报,2018(03)., articleTitle=null, refAbstract=null), Reference(id=1319955810470441782, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[9], rfOrder=8, authorNames=null, journalName=null, refType=null, unstructuredReference=Qing Xin,Bo Bai,Wenyan Liu.The analgesic effects of oxytocin in the peripheral and central nervous system[J].Neurochemistry International,2016., articleTitle=null, refAbstract=null), Reference(id=1319955810470441783, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[10], rfOrder=9, authorNames=null, journalName=null, refType=null, unstructuredReference=任冬冬,梁卓,崔应麟,郭燕可.加味散偏汤治疗风痰瘀阻型偏头痛46例临床观察[J].中医杂志,2017(03)., articleTitle=null, refAbstract=null), Reference(id=1319955810470441784, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[11], rfOrder=10, authorNames=null, journalName=null, refType=null, unstructuredReference=吴谊锋,王霖.散偏汤联合盐酸氟桂利嗪胶囊治疗偏头痛44例[J].浙江中医杂志,2022(08)., articleTitle=null, refAbstract=null), Reference(id=1319955810470441785, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[12], rfOrder=11, authorNames=null, journalName=null, refType=null, unstructuredReference=金海娣,潘梦雄,陈媚娇,刘恺鸣.偏头痛脑能量代谢机制[J].中国现代神经疾病杂志,2022(02)., articleTitle=null, refAbstract=null), Reference(id=1319955810470441786, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[13], rfOrder=12, authorNames=null, journalName=null, refType=null, unstructuredReference=王丹丹,崔应麟.浅谈加味散偏汤对治疗偏头痛的分析[J].中医临床研究,2018(12)., articleTitle=null, refAbstract=null), Reference(id=1319955810470441787, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[14], rfOrder=13, authorNames=null, journalName=null, refType=null, unstructuredReference=聂娜,沈琼颖,黄睿,叶思婷,陈乐,周传龙,梁宜.不同频率电针改善偏头痛患者头痛及焦虑抑郁症状的差异性研究-随机临床试验（英文）[J].World Journal of Acupuncture-Moxibustion,2023(03)., articleTitle=null, refAbstract=null), Reference(id=1319955810474636079, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[15], rfOrder=14, authorNames=null, journalName=null, refType=null, unstructuredReference=Wei Li,Xiaojun Diao,Chunfu Chen,Congcong Li,Yingbo Zhang,Yingying Li.Changes in hormones of the hypothalamic-pituitary-gonadal axis in migraine patients[J].Journal of Clinical Neuroscience,2018., articleTitle=null, refAbstract=null), Reference(id=1319955810474636080, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[16], rfOrder=15, authorNames=null, journalName=null, refType=null, unstructuredReference=付勇,董志威,周旭,李琳慧,刘慧,喻文,廖璐,章海凤.中医方案治疗偏头痛的贝叶斯网状Meta分析[J].世界科学技术-中医药现代化,2022(11)., articleTitle=null, refAbstract=null), Reference(id=1319955810474636081, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[17], rfOrder=16, authorNames=null, journalName=null, refType=null, unstructuredReference=徐进,刘梦琳,张道培,张怀亮.柴芩温胆汤治疗前庭性偏头痛[J].中医学报,2023(10)., articleTitle=null, refAbstract=null), Reference(id=1319955810474636082, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[18], rfOrder=17, authorNames=null, journalName=null, refType=null, unstructuredReference=Margarida Martins-Oliveira,Simon Akerman,Philip R. Holland,Jan R. Hoffmann,Isaura Tavares,Peter J. Goadsby.Neuroendocrine signaling modulates specific neural networks relevant to migraine[J].Neurobiology of Disease,2017., articleTitle=null, refAbstract=null), Reference(id=1319955810474636083, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[19], rfOrder=18, authorNames=null, journalName=null, refType=null, unstructuredReference=牟翔宇,孙鹏,薛玲,郭英慧,高冬梅,王杰琼,宇庆迎,乔明琦.基于整体观念探讨中医药应用蛋白质组学的研究进展[J].中华中医药杂志,2021(11)., articleTitle=null, refAbstract=null), Reference(id=1319955810474636084, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[20], rfOrder=19, authorNames=null, journalName=null, refType=null, unstructuredReference=梁洁.SIRT1在大鼠慢性偏头痛模型TNC部位表达及对线粒体能量代谢异常作用研究[D].重庆医科大学,2020(01)., articleTitle=null, refAbstract=null), Reference(id=1319955810474636085, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[21], rfOrder=20, authorNames=null, journalName=null, refType=null, unstructuredReference=刘燕.中医药治疗偏头痛用药规律及散偏汤对偏头痛模型大鼠CGRP、PENK的实验研究[D].北京中医药大学,2019(07)., articleTitle=null, refAbstract=null), Reference(id=1319955810474636086, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[22], rfOrder=21, authorNames=null, journalName=null, refType=null, unstructuredReference=南淞华,彭超杰,庞伯通,陈芳芳,葛文静,崔应麟.基于CiteSpace的中医药防治偏头痛的知识图谱分析[J].中国医药导报,2023(06)., articleTitle=null, refAbstract=null), Reference(id=1319955810474636087, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[23], rfOrder=22, authorNames=null, journalName=null, refType=null, unstructuredReference=Michael J. Lacagnina,Linda R. Watkins,Peter M. Grace.Toll-like receptors and their role in persistent pain[J].Pharmacology and Therapeutics,2018., articleTitle=null, refAbstract=null)], funds=[Fund(id=1319955809988096812, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, awardId=2042174706458525698, language=CN, fundingSource=2022年度河南省重点研发专项项目, fundOrder=null, country=null), Fund(id=1319955810118120237, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, awardId=2042174706462720002, language=CN, fundingSource=河南中医药大学2022年度研究生科研创新能力提升计划项目, fundOrder=null, country=null)], companyList=[AuthorCompany(id=1319955807718978325, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, xref=1, ext=[AuthorCompanyExt(id=1319955807727366934, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, companyId=1319955807718978325, language=CN, country=null, province=null, city=null, postcode=null, companyName=河南中医药大学第二临床医学院, departmentName=null, remark=^1.河南中医药大学第二临床医学院)]), AuthorCompany(id=1319955808088077079, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, xref=2, ext=[AuthorCompanyExt(id=1319955808096465688, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955805596660499, companyId=1319955808088077079, language=CN, country=null, province=null, city=null, postcode=null, companyName=河南中医药大学第二附属医院/河南省中医院, departmentName=null, remark=^2.河南中医药大学第二附属医院/河南省中医院)])], figs=null, attaches=null, journal=Journal(id=1315120739373908093, delFlag=0, nameCn=中医学报, nameEn=Acta Chinese Medicine, nameHistory1=null, nameHistory2=null, issn=1674-8999, eissn=null, cn=41-1411/R, coden=null, periodic=0, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=8b94oSAFH8bu+kilqGRUOQ==, journalPrice=null, startedYear=null, abbrevIsoEn=Acta Chinese Medicine, journalRemark=null, publicationField=null, createdTime=1791478818030, updatedTime=1791479792022, createdBy=18614031015, updatedBy=13701087609, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Medical and Pharmaceutical Sciences, subjectName=null, subjectCodeEn=Medical and Pharmaceutical Sciences, subjectNameEn=null, picCn=8b94oSAFH8bu+kilqGRUOQ==, picEn=Y56h/oCYJegF4hgM5ASRZw==, jcr=null, cjcr=null, exts=[JournalExt(id=1315124824696017555, language=CN, name=中医学报, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1791479792045, updatedTime=1791479792045, createdBy=13701087609, updatedBy=13701087609, submissionGuidelinesUrl=, submissionAuthorUrl=https://hnzyydx.portal.founderss.cn, submissionEditorUrl=https://journal.ids.fzyun.cn/auth/realms/journal/protocol/openid-connect/auth?client_id=journal-portal&redirect_uri=https%3A%2F%2Fjournal.portal.founderss.cn%2Foauth%2Fcallback&response_type=code&scope=phone+openid+email+profile&state=6c31f9e3-672c-4715-b, submissionReviewUrl=https://hnzyydx.portal.founderss.cn, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1315124824763126420, language=EN, name=Acta Chinese Medicine, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1791479792061, updatedTime=1791479792061, createdBy=13701087609, updatedBy=13701087609, submissionGuidelinesUrl=, submissionAuthorUrl=https://hnzyydx.portal.founderss.cn, submissionEditorUrl=https://journal.ids.fzyun.cn/auth/realms/journal/protocol/openid-connect/auth?client_id=journal-portal&redirect_uri=https%3A%2F%2Fjournal.portal.founderss.cn%2Foauth%2Fcallback&response_type=code&scope=phone+openid+email+profile&state=6c31f9e3-672c-4715-b, submissionReviewUrl=https://hnzyydx.portal.founderss.cn, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1315121837170065538, websiteList=[Website(id=1315346106557518446, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1315121837170065538, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zyxb/CN, language=CN, createTime=1791532549752, createBy=18614031015, updateTime=1791532766964, updateBy=18614031015, name=中医学报-中文, tplId=1146099689490845704, title=中医学报, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1315347175865963357, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=articleTextType, value=kx, createTime=1791532804695, updateTime=1791532804695, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175811437402, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=banner, value=null, createTime=1791532804682, updateTime=1791532804682, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175916295008, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=grayFlag, value=0, createTime=1791532804707, updateTime=1791532804707, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175790465881, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=logo, value=https://castjournals.cast.org.cn/joweb/zyxb/CN/file/pic?fileId=vxJwzD/oKgABLDx+COUqfw==, createTime=1791532804677, updateTime=1791532804677, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175954043746, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=minRunFlag, value=0, createTime=1791532804716, updateTime=1791532804716, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175849186140, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zyxb/CN/file/pic, createTime=1791532804691, updateTime=1791532804691, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175941460833, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=silenceFlag, value=0, createTime=1791532804713, updateTime=1791532804713, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175832408923, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1791532804687, updateTime=1791532804687, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175882740574, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=themeColor, value=null, createTime=1791532804699, updateTime=1791532804699, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175895323487, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=themeStyle, value=null, createTime=1791532804702, updateTime=1791532804702, creator=18614031015, updator=18614031015)]), Website(id=1315346107010503292, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1315121837170065538, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zyxb/EN, language=EN, createTime=1791532549860, createBy=18614031015, updateTime=1791532762834, updateBy=18614031015, name=中医学报-英文, tplId=1146101810881728533, title=Acta Chinese Medicine, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1315347133386052431, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=articleTextType, value=kx, createTime=1791532794567, updateTime=1791532794567, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133339915084, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=banner, value=null, createTime=1791532794556, updateTime=1791532794556, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133427995474, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=grayFlag, value=0, createTime=1791532794577, updateTime=1791532794577, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133318943563, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=logo, value=https://castjournals.cast.org.cn/joweb/zyxb/EN/file/pic?fileId=vxJwzD/oKgABLDx+COUqfw==, createTime=1791532794551, updateTime=1791532794551, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133448966996, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=minRunFlag, value=0, createTime=1791532794582, updateTime=1791532794582, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133369275214, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zyxb/EN/file/pic, createTime=1791532794563, updateTime=1791532794563, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133440578387, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=silenceFlag, value=0, createTime=1791532794580, updateTime=1791532794580, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133360886605, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1791532794561, updateTime=1791532794561, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133411218256, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=themeColor, value=null, createTime=1791532794573, updateTime=1791532794573, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133419606865, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=themeStyle, value=null, createTime=1791532794575, updateTime=1791532794575, creator=18614031015, updator=18614031015)])], journalTitle=中医学报, weixinUrl=null, journalUrl=https://hnzk.publish.founderss.cn/, iacademicId=null, status=1, seqNo=null, journalTitleEn=Acta Chinese Medicine, journalPhotoCn=8b94oSAFH8bu+kilqGRUOQ==, journalPhotoEn=Y56h/oCYJegF4hgM5ASRZw==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zyxb/CN/10.16368/j.issn.1674-8999.2026.01.024, detailUrlEn=https://castjournals.cast.org.cn/joweb/zyxb/EN/10.16368/j.issn.1674-8999.2026.01.024, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zyxb/CN/PDF/10.16368/j.issn.1674-8999.2026.01.024, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zyxb/EN/PDF/10.16368/j.issn.1674-8999.2026.01.024, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1792631587646, fullTextJson=null, articleText=null, reference=null)