Article(id=1319955746561831227, tenantId=1146029695717560320, journalId=1315121837170065538, issueId=1319955707420586876, articleNumber=PA20260409_CuwQLV9h, orderNo=null, doi=10.16368/j.issn.1674-8999.2026.01.008, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792631573572, onlineDateStr=2026-10-22, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792631573571, onlineIssueDateStr=2026-10-22, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792631573571, creator=admin, updateTime=1792631573571, updator=admin, issue=Issue{id=1319955707420586876, tenantId=1146029695717560320, journalId=1315121837170065538, year='2026', volume='41', issue='1', pageStart='1', pageEnd='141', issueExtLink='null', onlineDate='null', pubDate='1767974400000', pubDateStr='2026-01-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=0, articleOrder=1, issueType=1, specialIssue=null, createTime=1792631564240, creator='ztmeta', updateTime=1792997687704, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1321491340635001527, tenantId=1146029695717560320, journalId=1315121837170065538, issueId=1319955707420586876, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1321491340635001528, tenantId=1146029695717560320, journalId=1315121837170065538, issueId=1319955707420586876, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=48, endPage=57, ext={CN=ArticleExt(id=1319955746696048956, articleId=1319955746561831227, tenantId=1146029695717560320, journalId=1315121837170065538, language=CN, title=基于双向两样本孟德尔随机化研究探讨“肺胃相关”理论的现代内涵, columnId=null, journalTitle=中医学报, columnName=创新思维与技术前沿, runingTitle=null, highlight=null, articleAbstract=目的:基于孟德尔随机化（Mendelian randomization,MR）研究探讨呼吸系统疾病和消化系统疾病之间的因果关系，阐释“肺胃相关”理论的现代医学内涵。方法:基于全基因组关联研究（Genome-wide association studies,GWAS）数据，利用双向两样本MR方法，将具有显著差异性的单核苷酸多态性（single nucleotide polymorphism,SNP）作为工具变量，评价16种代表“肺气上逆”的呼吸系统疾病和3种代表“胃气上逆”的消化系统疾病之间的因果关系。结果:胃食管反流病与慢性阻塞性肺疾病(OR:1.48,P=6.43×10⁻¹⁵)、哮喘(OR:1.49,P=5.71×10⁻²⁶)、肺炎(OR:1.17,P=1.84×10⁻⁷)、细菌性肺炎(OR:1.18,P=1.04×10⁻⁴)和支气管炎(OR:1.24,P=2.53×10⁻¹⁶)的风险增加显著相关，与降低FEV₁(OR:0.91,P=2.90×10⁻¹¹)和降低FVC(OR:0.89,P=6.48×10⁻¹⁶)显著相关。巴雷特食管与哮喘(OR:1.08,P=1.37×10⁻³)、肺栓塞(OR:1.10,P=3.15×10⁻²)风险增加提示性相关;食管裂孔疝与细菌性肺炎(OR:1.25,P=2.78×10⁻²)的风险增加提示性相关。多重敏感性分析证实了结果的稳健性。结论:呼吸系统疾病与消化系统疾病存在因果关系，从遗传学的角度阐释了“肺胃相关”理论，为肺系疾病“肺胃同降”的防治思路提供新证据。, authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null)}, authors=[Author(id=1319955746977067329, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=王乔, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=["13910331107@139.com"], emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955747073536324, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, authorId=1319955746977067329, language=CN, stringName=王乔, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,², address=^1.中日友好医院中西医结合肺病一部,^2.北京中医药大学研究生院中日友好医院中西医结合肺病一部, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955746826072381, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=1, ext=[AuthorCompanyExt(id=1319955746830266686, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746826072381, language=CN, country=null, province=null, city=null, postcode=null, companyName=中日友好医院中西医结合肺病一部, departmentName=null, remark=^1.中日友好医院中西医结合肺病一部)]), AuthorCompany(id=1319955746905764159, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=2, ext=[AuthorCompanyExt(id=1319955746914152768, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746905764159, language=CN, country=null, province=null, city=null, postcode=null, companyName=北京中医药大学研究生院, departmentName=null, remark=^2.北京中医药大学研究生院)])]), Author(id=1319955747136450885, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=刘源, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955747274862920, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, authorId=1319955747136450885, language=CN, stringName=刘源, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,², address=^1.中日友好医院中西医结合肺病一部,^2.北京中医药大学研究生院中日友好医院中西医结合肺病一部, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955746826072381, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=1, ext=[AuthorCompanyExt(id=1319955746830266686, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746826072381, language=CN, country=null, province=null, city=null, postcode=null, companyName=中日友好医院中西医结合肺病一部, departmentName=null, remark=^1.中日友好医院中西医结合肺病一部)]), AuthorCompany(id=1319955746905764159, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=2, ext=[AuthorCompanyExt(id=1319955746914152768, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746905764159, language=CN, country=null, province=null, city=null, postcode=null, companyName=北京中医药大学研究生院, departmentName=null, remark=^2.北京中医药大学研究生院)])]), Author(id=1319955747341971785, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=赵泽正, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955747434246476, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, authorId=1319955747341971785, language=CN, stringName=赵泽正, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,², address=^1.中日友好医院中西医结合肺病一部,^2.北京中医药大学研究生院中日友好医院中西医结合肺病一部, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955746826072381, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=1, ext=[AuthorCompanyExt(id=1319955746830266686, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746826072381, language=CN, country=null, province=null, city=null, postcode=null, companyName=中日友好医院中西医结合肺病一部, departmentName=null, remark=^1.中日友好医院中西医结合肺病一部)]), AuthorCompany(id=1319955746905764159, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=2, ext=[AuthorCompanyExt(id=1319955746914152768, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746905764159, language=CN, country=null, province=null, city=null, postcode=null, companyName=北京中医药大学研究生院, departmentName=null, remark=^2.北京中医药大学研究生院)])]), Author(id=1319955749099385165, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=崔佳旗, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955749304906064, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, authorId=1319955749099385165, language=CN, stringName=崔佳旗, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,², address=^1.中日友好医院中西医结合肺病一部,^2.北京中医药大学研究生院中日友好医院中西医结合肺病一部, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955746826072381, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=1, ext=[AuthorCompanyExt(id=1319955746830266686, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746826072381, language=CN, country=null, province=null, city=null, postcode=null, companyName=中日友好医院中西医结合肺病一部, departmentName=null, remark=^1.中日友好医院中西医结合肺病一部)]), AuthorCompany(id=1319955746905764159, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=2, ext=[AuthorCompanyExt(id=1319955746914152768, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746905764159, language=CN, country=null, province=null, city=null, postcode=null, companyName=北京中医药大学研究生院, departmentName=null, remark=^2.北京中医药大学研究生院)])]), Author(id=1319955749376209233, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, orderNo=5, firstName=null, middleName=null, lastName=null, nameCn=贺心贻, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955749489455444, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, authorId=1319955749376209233, language=CN, stringName=贺心贻, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,², address=^1.中日友好医院中西医结合肺病一部,^2.北京中医药大学研究生院中日友好医院中西医结合肺病一部, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955746826072381, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=1, ext=[AuthorCompanyExt(id=1319955746830266686, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746826072381, language=CN, country=null, province=null, city=null, postcode=null, companyName=中日友好医院中西医结合肺病一部, departmentName=null, remark=^1.中日友好医院中西医结合肺病一部)]), AuthorCompany(id=1319955746905764159, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=2, ext=[AuthorCompanyExt(id=1319955746914152768, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746905764159, language=CN, country=null, province=null, city=null, postcode=null, companyName=北京中医药大学研究生院, departmentName=null, remark=^2.北京中医药大学研究生院)])]), Author(id=1319955749619478869, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, orderNo=6, firstName=null, middleName=null, lastName=null, nameCn=李佳文, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955749783056728, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, authorId=1319955749619478869, language=CN, stringName=李佳文, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,², address=^1.中日友好医院中西医结合肺病一部,^2.北京中医药大学研究生院中日友好医院中西医结合肺病一部, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955746826072381, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=1, ext=[AuthorCompanyExt(id=1319955746830266686, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746826072381, language=CN, country=null, province=null, city=null, postcode=null, companyName=中日友好医院中西医结合肺病一部, departmentName=null, remark=^1.中日友好医院中西医结合肺病一部)]), AuthorCompany(id=1319955746905764159, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=2, ext=[AuthorCompanyExt(id=1319955746914152768, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746905764159, language=CN, country=null, province=null, city=null, postcode=null, companyName=北京中医药大学研究生院, departmentName=null, remark=^2.北京中医药大学研究生院)])]), Author(id=1319955749875331417, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, orderNo=7, firstName=null, middleName=null, lastName=null, nameCn=赵欣然, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955749950828893, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, authorId=1319955749875331417, language=CN, stringName=赵欣然, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,², address=^1.中日友好医院中西医结合肺病一部,^2.北京中医药大学研究生院中日友好医院中西医结合肺病一部, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955746826072381, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=1, ext=[AuthorCompanyExt(id=1319955746830266686, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746826072381, language=CN, country=null, province=null, city=null, postcode=null, companyName=中日友好医院中西医结合肺病一部, departmentName=null, remark=^1.中日友好医院中西医结合肺病一部)]), AuthorCompany(id=1319955746905764159, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=2, ext=[AuthorCompanyExt(id=1319955746914152768, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746905764159, language=CN, country=null, province=null, city=null, postcode=null, companyName=北京中医药大学研究生院, departmentName=null, remark=^2.北京中医药大学研究生院)])]), Author(id=1319955750026326366, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, orderNo=8, firstName=null, middleName=null, lastName=null, nameCn=杨道文, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955750110212449, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, authorId=1319955750026326366, language=CN, stringName=杨道文, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,², address=^1.中日友好医院中西医结合肺病一部,^2.北京中医药大学研究生院中日友好医院中西医结合肺病一部, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955746826072381, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=1, ext=[AuthorCompanyExt(id=1319955746830266686, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746826072381, language=CN, country=null, province=null, city=null, postcode=null, companyName=中日友好医院中西医结合肺病一部, departmentName=null, remark=^1.中日友好医院中西医结合肺病一部)]), AuthorCompany(id=1319955746905764159, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=2, ext=[AuthorCompanyExt(id=1319955746914152768, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746905764159, language=CN, country=null, province=null, city=null, postcode=null, companyName=北京中医药大学研究生院, departmentName=null, remark=^2.北京中医药大学研究生院)])])], keywords=[Keyword(id=1319955750206681442, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, language=CN, orderNo=1, keyword=肺胃相关), Keyword(id=1319955750265401699, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, language=CN, orderNo=2, keyword=孟德尔随机化), Keyword(id=1319955750324121956, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, language=CN, orderNo=3, keyword=呼吸系统疾病), Keyword(id=1319955750387036517, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, language=CN, orderNo=4, keyword=消化系统疾病), Keyword(id=1319955750458339686, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, language=CN, orderNo=5, keyword=肺胃同降), Keyword(id=1319955750517059943, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, language=CN, orderNo=6, keyword=中医药)], refs=[Reference(id=1319955750781301098, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[1], rfOrder=0, authorNames=null, journalName=null, refType=null, unstructuredReference=张明发,沈雅琴.中药厚朴对胃的保护作用及其药理机制的研究进展[J].抗感染药学,2022(07)., articleTitle=null, refAbstract=null), Reference(id=1319955750781301099, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[2], rfOrder=1, authorNames=null, journalName=null, refType=null, unstructuredReference=Michael F. Vaezi.Chronic Cough and Gastroesophageal Reflux Disease: How Do We Establish a Causal Link?[J].Chest,2013., articleTitle=null, refAbstract=null), Reference(id=1319955750781301100, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[3], rfOrder=2, authorNames=null, journalName=null, refType=null, unstructuredReference=崔红生,武维屏.从中医整体观谈变态反应性疾病从肺论治[J].中医杂志,2011(19)., articleTitle=null, refAbstract=null), Reference(id=1319955750781301101, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[4], rfOrder=3, authorNames=null, journalName=null, refType=null, unstructuredReference=杨道文,单大玲.肺胃同降理论在肺系疾病中的应用[J].中国中医药现代远程教育,2010(01)., articleTitle=null, refAbstract=null), Reference(id=1319955750781301102, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[5], rfOrder=4, authorNames=null, journalName=null, refType=null, unstructuredReference=招金娣,廖凌虹.基于脂质代谢重编程探讨健脾化痰法调节结直肠癌肿瘤微环境[J].河南中医,2024(09)., articleTitle=null, refAbstract=null), Reference(id=1319955750781301103, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[6], rfOrder=5, authorNames=null, journalName=null, refType=null, unstructuredReference=谢朝荣,陶庆锋,胡缤予,周梦荻,郑晖,赵凌.孟德尔随机化研究及其在中医药领域的应用展望[J].中医杂志,2023(05)., articleTitle=null, refAbstract=null), Reference(id=1319955750781301104, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[7], rfOrder=6, authorNames=null, journalName=null, refType=null, unstructuredReference=周亚丽,杨萍,李喜香,李小凤.半夏化学成分与药理作用研究进展及其质量标志物（Q-Marker）预测[J].中草药,2024(14)., articleTitle=null, refAbstract=null), Reference(id=1319955750781301105, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[8], rfOrder=7, authorNames=null, journalName=null, refType=null, unstructuredReference=牛峥,马丽萍,姚铁,丁丽琴,邱峰,张德芹.旋覆花化学成分及药理作用研究进展[J].药物评价研究,2022(12)., articleTitle=null, refAbstract=null), Reference(id=1319955750781301106, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[9], rfOrder=8, authorNames=null, journalName=null, refType=null, unstructuredReference=王雪茹,程思益,吕天宜,李璐,杨道文.益气疏风降胃法治疗咳嗽变异性哮喘气虚风动、肺胃气逆证的临床观察[J].中华中医药杂志,2020(06)., articleTitle=null, refAbstract=null), Reference(id=1319955750781301107, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[10], rfOrder=9, authorNames=null, journalName=null, refType=null, unstructuredReference=张明发,沈雅琴.厚朴提取物及其有效成分的呼吸系统药理作用研究进展[J].药物评价研究,2024(04)., articleTitle=null, refAbstract=null), Reference(id=1319955750781301108, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[11], rfOrder=10, authorNames=null, journalName=null, refType=null, unstructuredReference=武会珠,张效科.基于“聚于胃，关于肺”探讨仲景治咳用药规律[J].辽宁中医药大学学报,2024(08)., articleTitle=null, refAbstract=null)], funds=[Fund(id=1319955750621917544, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, awardId=2042174464224886786, language=CN, fundingSource=国家重点研发计划项目, fundOrder=null, country=null), Fund(id=1319955750684832105, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, awardId=2042174464224886787, language=CN, fundingSource=兵团财政科技计划项目, fundOrder=null, country=null)], companyList=[AuthorCompany(id=1319955746826072381, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=1, ext=[AuthorCompanyExt(id=1319955746830266686, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746826072381, language=CN, country=null, province=null, city=null, postcode=null, companyName=中日友好医院中西医结合肺病一部, departmentName=null, remark=^1.中日友好医院中西医结合肺病一部)]), AuthorCompany(id=1319955746905764159, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, xref=2, ext=[AuthorCompanyExt(id=1319955746914152768, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955746561831227, companyId=1319955746905764159, language=CN, country=null, province=null, city=null, postcode=null, companyName=北京中医药大学研究生院, departmentName=null, remark=^2.北京中医药大学研究生院)])], figs=null, attaches=null, journal=Journal(id=1315120739373908093, delFlag=0, nameCn=中医学报, nameEn=Acta Chinese Medicine, nameHistory1=null, nameHistory2=null, issn=1674-8999, eissn=null, cn=41-1411/R, coden=null, periodic=0, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=8b94oSAFH8bu+kilqGRUOQ==, journalPrice=null, startedYear=null, abbrevIsoEn=Acta Chinese Medicine, journalRemark=null, publicationField=null, createdTime=1791478818030, updatedTime=1791479792022, createdBy=18614031015, updatedBy=13701087609, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Medical and Pharmaceutical Sciences, subjectName=null, subjectCodeEn=Medical and Pharmaceutical Sciences, subjectNameEn=null, picCn=8b94oSAFH8bu+kilqGRUOQ==, picEn=Y56h/oCYJegF4hgM5ASRZw==, jcr=null, cjcr=null, exts=[JournalExt(id=1315124824696017555, language=CN, name=中医学报, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1791479792045, updatedTime=1791479792045, createdBy=13701087609, updatedBy=13701087609, submissionGuidelinesUrl=, submissionAuthorUrl=https://hnzyydx.portal.founderss.cn, submissionEditorUrl=https://journal.ids.fzyun.cn/auth/realms/journal/protocol/openid-connect/auth?client_id=journal-portal&redirect_uri=https%3A%2F%2Fjournal.portal.founderss.cn%2Foauth%2Fcallback&response_type=code&scope=phone+openid+email+profile&state=6c31f9e3-672c-4715-b, submissionReviewUrl=https://hnzyydx.portal.founderss.cn, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1315124824763126420, language=EN, name=Acta Chinese Medicine, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1791479792061, updatedTime=1791479792061, createdBy=13701087609, updatedBy=13701087609, submissionGuidelinesUrl=, submissionAuthorUrl=https://hnzyydx.portal.founderss.cn, submissionEditorUrl=https://journal.ids.fzyun.cn/auth/realms/journal/protocol/openid-connect/auth?client_id=journal-portal&redirect_uri=https%3A%2F%2Fjournal.portal.founderss.cn%2Foauth%2Fcallback&response_type=code&scope=phone+openid+email+profile&state=6c31f9e3-672c-4715-b, submissionReviewUrl=https://hnzyydx.portal.founderss.cn, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1315121837170065538, websiteList=[Website(id=1315346106557518446, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1315121837170065538, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zyxb/CN, language=CN, createTime=1791532549752, createBy=18614031015, updateTime=1791532766964, updateBy=18614031015, name=中医学报-中文, tplId=1146099689490845704, title=中医学报, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1315347175865963357, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=articleTextType, value=kx, createTime=1791532804695, updateTime=1791532804695, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175811437402, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=banner, value=null, createTime=1791532804682, updateTime=1791532804682, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175916295008, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=grayFlag, value=0, createTime=1791532804707, updateTime=1791532804707, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175790465881, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=logo, value=https://castjournals.cast.org.cn/joweb/zyxb/CN/file/pic?fileId=vxJwzD/oKgABLDx+COUqfw==, createTime=1791532804677, updateTime=1791532804677, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175954043746, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=minRunFlag, value=0, createTime=1791532804716, updateTime=1791532804716, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175849186140, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zyxb/CN/file/pic, createTime=1791532804691, updateTime=1791532804691, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175941460833, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=silenceFlag, value=0, createTime=1791532804713, updateTime=1791532804713, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175832408923, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1791532804687, updateTime=1791532804687, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175882740574, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=themeColor, value=null, createTime=1791532804699, updateTime=1791532804699, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175895323487, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=themeStyle, value=null, createTime=1791532804702, updateTime=1791532804702, creator=18614031015, updator=18614031015)]), Website(id=1315346107010503292, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1315121837170065538, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zyxb/EN, language=EN, createTime=1791532549860, createBy=18614031015, updateTime=1791532762834, updateBy=18614031015, name=中医学报-英文, tplId=1146101810881728533, title=Acta Chinese Medicine, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1315347133386052431, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=articleTextType, value=kx, createTime=1791532794567, updateTime=1791532794567, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133339915084, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=banner, value=null, createTime=1791532794556, updateTime=1791532794556, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133427995474, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=grayFlag, value=0, createTime=1791532794577, updateTime=1791532794577, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133318943563, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=logo, value=https://castjournals.cast.org.cn/joweb/zyxb/EN/file/pic?fileId=vxJwzD/oKgABLDx+COUqfw==, createTime=1791532794551, updateTime=1791532794551, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133448966996, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=minRunFlag, value=0, createTime=1791532794582, updateTime=1791532794582, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133369275214, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zyxb/EN/file/pic, createTime=1791532794563, updateTime=1791532794563, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133440578387, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=silenceFlag, value=0, createTime=1791532794580, updateTime=1791532794580, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133360886605, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1791532794561, updateTime=1791532794561, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133411218256, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=themeColor, value=null, createTime=1791532794573, updateTime=1791532794573, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133419606865, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=themeStyle, value=null, createTime=1791532794575, updateTime=1791532794575, creator=18614031015, updator=18614031015)])], journalTitle=中医学报, weixinUrl=null, journalUrl=https://hnzk.publish.founderss.cn/, iacademicId=null, status=1, seqNo=null, journalTitleEn=Acta Chinese Medicine, journalPhotoCn=8b94oSAFH8bu+kilqGRUOQ==, journalPhotoEn=Y56h/oCYJegF4hgM5ASRZw==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zyxb/CN/10.16368/j.issn.1674-8999.2026.01.008, detailUrlEn=https://castjournals.cast.org.cn/joweb/zyxb/EN/10.16368/j.issn.1674-8999.2026.01.008, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zyxb/CN/PDF/10.16368/j.issn.1674-8999.2026.01.008, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zyxb/EN/PDF/10.16368/j.issn.1674-8999.2026.01.008, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1792631573571, fullTextJson=null, articleText=null, reference=null)