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tenantId=1146029695717560320, journalId=1315121837170065538, language=CN, title=动脉粥样硬化相关泛血管疾病的中医病机与治疗策略, columnId=null, journalTitle=中医学报, columnName=专题研究:动脉粥样硬化的中医药防治策略, runingTitle=null, highlight=null, articleAbstract=泛血管疾病(panvascular diseases)是以动脉粥样硬化(atherosclerosis,AS)为核心病理改变的全身性血管病变综合征，泛血管疾病虽以整体阴阳失衡，寒邪内生为本，然其病机演变与脏腑功能失调密切相关，尤以心、脾、肾三脏为要。AS相关泛血管疾病以“阴阳失衡”为核心病机，其本质在于阳气虚损与阴邪壅盛的交织，心阳不足则血行无力，脾阳虚弱则痰湿内生，肾阳亏虚则气化无权，导致寒邪内生，寒伏脉络则痰、瘀等病理产物聚集，久则伤及脉道，导致相应疾病的发生。临证应以“温阳固本，燮理阴阳”为治疗总纲，旨在通过温通心阳、健运脾阳、温补肾阳的三脏同调策略，重建机体阴阳动态平衡。同时根据斑块形成不同阶段进行分期论治，实现精准干预。疾病初期痰瘀初结，脉络尚未瘀滞，症状不显，治当健运中焦，温化浊邪。病情进展至中期，痰瘀纠结成斑，管腔逐渐狭窄，此时痰浊血瘀征象明显，治当祛瘀化痰，散结消斑为主。及至末期，痰浊瘀血阻滞日久化生邪热，酿生浊毒，毒热壅滞，斑块破裂之际，急当清热解毒、稳定易损斑块，预防AS进展。, authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, 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