Article(id=1315688442227441964, tenantId=1146029695717560320, journalId=1315121837170065538, issueId=1315688435411694395, articleNumber=null, orderNo=null, doi=10.16368/j.issn.1674-8999.2025.12.397, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1750003200000, receivedDateStr=2025-06-16, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791614168935, onlineDateStr=2026-10-10, pubDate=1765296000000, pubDateStr=2025-12-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791614168935, onlineIssueDateStr=2026-10-10, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791614168935, creator=13701087609, updateTime=1791614168935, updator=13701087609, issue=Issue{id=1315688435411694395, tenantId=1146029695717560320, journalId=1315121837170065538, year='2025', volume='40', issue='12', pageStart='2487', pageEnd='2712', issueExtLink='null', onlineDate='null', pubDate='1765296000000', pubDateStr='2025-12-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791614167309, creator='13701087609', updateTime=1791616084449, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1315696476567744680, tenantId=1146029695717560320, journalId=1315121837170065538, issueId=1315688435411694395, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1315696476571938985, tenantId=1146029695717560320, journalId=1315121837170065538, issueId=1315688435411694395, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=2543, endPage=2548, ext={EN=ArticleExt(id=1315688442466517294, articleId=1315688442227441964, tenantId=1146029695717560320, journalId=1315121837170065538, language=EN, title=Treatment of Post-stroke Vertical Orifice Obstruction Based on Brain-Spleen and Stomach-Intestine Axis with Theory of″Toxin Damaged Brain Collaterals″, columnId=1315688442386825517, journalTitle=Acta Chinese Medicine, columnName=Treatise, runingTitle=null, highlight=null, articleAbstract=

The obstruction of the vertical orifice after stroke is closely related to the brain-Spleen and Stomach-intestine axis as well as the pathogenesis of″Toxin-damaged cerebral collaterals″.Marked by Wind，Fire，Phlegm，blood stasis，and Toxin，with disrupted Qi circulation as the root cause，detoxifying and opening the Fu is an important therapeutic principle for post-stroke vertical orifice obstruction.The brain，the Spleen and Stomach and the intestine are relatively unified in both function and structure:physiologically，they are generally interconnected in terms of meridian Qi circulation，Zang and Fu functions as well as the generation of fine substances；pathologically，post-stroke brain symptoms can affect intestinal responses，leading to a series of gastrointestinal complications. Conversely，gastrointestinal dysfunction can disturb the brain's orifices，causing a loss of mental ability.As an initiating factor，Wind，Fire，Phlegm，stasis and Toxins coagulate intractably and ascend to attack the brain，damaging cerebral collaterals.Through the bridge function of the brain-Spleen and Stomach-intestine axis，this circulates throughout the body，causing viscera obstruction，and subsequently impairing both physical and mental aspects of the body. Clinically，emphasis should be placed on detoxifying and dredging the Fu，with acupuncture and medicine，and harmonizing the relationship between body and mind.In stroke，the disease is in the brain，but the treatment of dredging the Fu targets the stomach and intestines.Treating the upper disease from the lower organs，and descending the Yang ming meridian，allows the toxins ascending to the brain collaterals to be cleared via the brain-Spleen and Stomach-intestine axis，which effectively refreshes，promotes the circulation of Qi and blood，supports the Zheng Qi and benefits patient's recovery.

, authors=Mengfang XU, Xiao HAN, Linlu WU, Muzhao ZHANG, Tianjiao XU, Yuanyuan LI, Xinyue SHI, Yan SHEN, Juwei ZHANG, Kang WU, Tianzhu CHEN, Renzhao MA, Xirui SUN, Yuqing LIN, Yihuai ZOU, authorsList=Mengfang XU, Xiao HAN, Linlu WU, Muzhao ZHANG, Tianjiao XU, Yuanyuan LI, Xinyue SHI, Yan SHEN, Juwei ZHANG, Kang WU, Tianzhu CHEN, Renzhao MA, Xirui SUN, Yuqing LIN, Yihuai ZOU, authorCompany=null, correspAuthors=Yihuai ZOU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1315688442852393264, articleId=1315688442227441964, tenantId=1146029695717560320, journalId=1315121837170065538, language=CN, title=基于脑-脾胃-肠轴结合“毒损脑络”论治卒中后竖窍不通, columnId=1315688442575569199, journalTitle=中医学报, columnName=论著, runingTitle=null, highlight=null, articleAbstract=

卒中后竖窍不通与脑-脾胃-肠轴以及“毒损脑络”病机密切相关，以风火痰瘀毒为标，气机逆乱为本，解毒通腑为治疗卒中后竖窍不通的重要法则。脑与脾胃、肠在功能和结构上相对统一：从生理角度，三者在经络气机运行、脏腑机能以及化生精微物质方面存在普遍联系；从病理角度，中风后脑部症状会影响肠道反应，出现一系列胃肠道并发症。反之亦然，胃肠功能失常，邪气上扰脑窍，则致神明失守。作为始动因素的风火痰瘀诸毒胶结难解，并行上犯于脑，脑络受损，通过脑-脾胃-肠轴的桥梁作用，循环往复，流窜全身，腑窍滞塞，继而败坏机体形质与神质。临证当重视解毒通腑，针药并施，形神兼调。卒中病位在脑，通腑法治在胃肠，上病下治，通降阳明，使上犯脑络的毒邪随脑-脾胃-肠轴从下而解，有釜底抽薪、推陈出新、疏布气血之功，可顾护正气，利于患者的恢复。

, authors=徐梦方, 韩笑, 武琳璐, 张慕昭, 许天骄, 李媛媛, 史昕玥, 申艳, 张琚崴, 吴康, 陈天竹, 马任钊, 孙熙蕊, 林雨晴, 邹忆怀, authorsList=徐梦方, 韩笑, 武琳璐, 张慕昭, 许天骄, 李媛媛, 史昕玥, 申艳, 张琚崴, 吴康, 陈天竹, 马任钊, 孙熙蕊, 林雨晴, 邹忆怀, authorCompany=null, correspAuthors=邹忆怀, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=W5etkFCTfOBQ6TLxrDDR1g==, magXml=e6avPeBOur9ewUs7qShy/Q==, pdfUrl=null, pdf=ysWsAYfk7ccM07f4l6dLbQ==, pdfFileSize=1491776, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=sQUTLJ3t80C+km+zIa1MfA==, mapNumber=null, fund=null)}, authors=[Author(id=1315688443171160373, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1315688442227441964, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1315688443238269239, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1315688442227441964, authorId=1315688443171160373, language=EN, stringName=Mengfang XU, firstName=Mengfang, middleName=null, lastName=XU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing China 100700, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1315688443313766712, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1315688442227441964, authorId=1315688443171160373, language=CN, stringName=徐梦方, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=北京中医药大学东直门医院，北京 100700, bio={"content":"

徐梦方（1998 -），女，河南驻马店人，硕士研究生，研究方向：中医药防治脑病。

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徐梦方（1998 -），女，河南驻马店人，硕士研究生，研究方向：中医药防治脑病。

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