Article(id=1319955841525068797, tenantId=1146029695717560320, journalId=1315121837170065538, issueId=1319955707420586876, articleNumber=PA20260409_XYuGUTvo, orderNo=null, doi=10.16368/j.issn.1674-8999.2026.01.030, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792631596213, onlineDateStr=2026-10-22, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792631596212, onlineIssueDateStr=2026-10-22, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792631596212, creator=admin, updateTime=1792631596212, updator=admin, issue=Issue{id=1319955707420586876, tenantId=1146029695717560320, journalId=1315121837170065538, year='2026', volume='41', issue='1', pageStart='1', pageEnd='141', issueExtLink='null', onlineDate='null', pubDate='1767974400000', pubDateStr='2026-01-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=0, articleOrder=1, issueType=1, specialIssue=null, createTime=1792631564240, creator='ztmeta', updateTime=1792997687704, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1321491340635001527, tenantId=1146029695717560320, journalId=1315121837170065538, issueId=1319955707420586876, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1321491340635001528, tenantId=1146029695717560320, journalId=1315121837170065538, issueId=1319955707420586876, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=214, endPage=220, ext={CN=ArticleExt(id=1319955841671869438, articleId=1319955841525068797, tenantId=1146029695717560320, journalId=1315121837170065538, language=CN, title=犀角地黄汤联合阿加曲班治疗静脉溶栓时间窗内急性脑梗死, columnId=null, journalTitle=中医学报, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=目的:观察犀角地黄汤联合阿加曲班治疗静脉溶栓时间窗内急性脑梗死(acute cerebral infarction,ACI)的临床疗效及其对炎症因子、凝血和脑血流动力学的影响。方法:80例静脉溶栓时间窗内的ACI患者按照随机数字法平均分为对照组和联合组。对照组给予阿加曲班，联合组在对照组治疗基础上给予犀角地黄汤，7 d为1个疗程。比较两组患者治疗后临床疗效、改良Rankin量表(modified Rankin scale,mRS)以及治疗前后美国国立卫生院卒中量表(National Institutes of Health Stroke Scale,NIHSS)评分、瘀热证候积分、血清炎症因子水平[超敏C反应蛋白(hypersensitive C-reactive protein,h CRP)、血清脂蛋白相关磷脂酶A2(lipoprotein-associated phospholipase A2,Lp-PLA2)、同型半胱氨酸(homocysteine,Hcy)]、凝血功能[凝血酶原时间(prothrombin time,PT)、活化部分凝血酶原时间(activated partial thromboplastin time,APTT)、国际标准化比率(international normalized ratio,INR)、凝血酶时间(thrombin time,TT)、D-二聚体(D-dimer,DD)、纤维蛋白原(fibrinogen,FIB)]和大脑中动脉(middle cerebral artery,MCA)的血流动力学参数[收缩峰血流速度(peak systolic velocity,Vs)、舒张末期血流流速(end diastolic velocity,Vd)、平均血流速度(mean velocity,Vm)]。结果:(1)治疗后，两组患者NIHSS评分、瘀热证候评分均显著降低(P<0.01)，且联合组低于同期对照组(P<0.05)。(2)治疗后，联合组患者mRS评分低于对照组，有效率高于对照组(P<0.05)。(3)治疗后，两组患者h CRP、Lp-PLA2和Hcy水平均显著降低(P<0.01)，且联合组CRP水平低于同期对照组(P<0.05),Lp-PLA2和Hcy水平显著低于同期对照组(P<0.01 )。(4 )治疗后，两组患者PT、APTT、INR、TT水平均明显下降(P<0.01)，对照组DD和FIB水平显著降低(P<0.05)，且联合组DD和FIB水平低于同期对照组(P<0.05)。(5)治疗后，两组患者MCA Vs、Vd、Vm水平显著升高(P<0.01)，且联合组Vs、Vd、Vm高于同期对照组(P<0.05)。结论:犀角地黄汤联合加曲班治疗静脉溶栓时间窗内ACI疗效确切，可改善患者神经功能缺损，提高生活能力，可能与降低患者血清炎症因子水平、改善凝血功能和增加局部脑血流有关。, authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null)}, authors=[Author(id=1319955843672551428, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=姜婧, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955843836129288, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, authorId=1319955843672551428, language=CN, stringName=姜婧, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,²,³, address=^1.南京大学医院,^2.江苏省中医药研究院,^3.南京中医药大学附属中西医结合医院南京大学医院, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955841785115647, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=1, ext=[AuthorCompanyExt(id=1319955841793504256, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955841785115647, language=CN, country=null, province=null, city=null, postcode=null, companyName=南京大学医院, departmentName=null, remark=^1.南京大学医院)]), AuthorCompany(id=1319955841885777920, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=2, ext=[AuthorCompanyExt(id=1319955841898360833, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955841885777920, language=CN, country=null, province=null, city=null, postcode=null, companyName=江苏省中医药研究院, departmentName=null, remark=^2.江苏省中医药研究院)]), AuthorCompany(id=1319955843546722306, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=3, ext=[AuthorCompanyExt(id=1319955843555110915, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955843546722306, language=CN, country=null, province=null, city=null, postcode=null, companyName=南京中医药大学附属中西医结合医院, departmentName=null, remark=^3.南京中医药大学附属中西医结合医院)])]), Author(id=1319955843949375497, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=钱冰冰, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955844037455885, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, authorId=1319955843949375497, language=CN, stringName=钱冰冰, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,²,³, address=^1.南京大学医院,^2.江苏省中医药研究院,^3.南京中医药大学附属中西医结合医院南京大学医院, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955841785115647, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=1, ext=[AuthorCompanyExt(id=1319955841793504256, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955841785115647, language=CN, country=null, province=null, city=null, postcode=null, companyName=南京大学医院, departmentName=null, remark=^1.南京大学医院)]), AuthorCompany(id=1319955841885777920, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=2, ext=[AuthorCompanyExt(id=1319955841898360833, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955841885777920, language=CN, country=null, province=null, city=null, postcode=null, companyName=江苏省中医药研究院, departmentName=null, remark=^2.江苏省中医药研究院)]), AuthorCompany(id=1319955843546722306, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=3, ext=[AuthorCompanyExt(id=1319955843555110915, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955843546722306, language=CN, country=null, province=null, city=null, postcode=null, companyName=南京中医药大学附属中西医结合医院, departmentName=null, remark=^3.南京中医药大学附属中西医结合医院)])]), Author(id=1319955844121341966, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=薛莲, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955844205228050, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, authorId=1319955844121341966, language=CN, stringName=薛莲, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,²,³, address=^1.南京大学医院,^2.江苏省中医药研究院,^3.南京中医药大学附属中西医结合医院南京大学医院, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955841785115647, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=1, ext=[AuthorCompanyExt(id=1319955841793504256, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955841785115647, language=CN, country=null, province=null, city=null, postcode=null, companyName=南京大学医院, departmentName=null, remark=^1.南京大学医院)]), AuthorCompany(id=1319955841885777920, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=2, ext=[AuthorCompanyExt(id=1319955841898360833, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955841885777920, language=CN, country=null, province=null, city=null, postcode=null, companyName=江苏省中医药研究院, departmentName=null, remark=^2.江苏省中医药研究院)]), AuthorCompany(id=1319955843546722306, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=3, ext=[AuthorCompanyExt(id=1319955843555110915, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955843546722306, language=CN, country=null, province=null, city=null, postcode=null, companyName=南京中医药大学附属中西医结合医院, departmentName=null, remark=^3.南京中医药大学附属中西医结合医院)])]), Author(id=1319955844335251475, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=李静波, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955844435914775, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, authorId=1319955844335251475, language=CN, stringName=李静波, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,²,³, address=^1.南京大学医院,^2.江苏省中医药研究院,^3.南京中医药大学附属中西医结合医院南京大学医院, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955841785115647, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=1, ext=[AuthorCompanyExt(id=1319955841793504256, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955841785115647, language=CN, country=null, province=null, city=null, postcode=null, companyName=南京大学医院, departmentName=null, remark=^1.南京大学医院)]), AuthorCompany(id=1319955841885777920, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=2, ext=[AuthorCompanyExt(id=1319955841898360833, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955841885777920, language=CN, country=null, province=null, city=null, postcode=null, companyName=江苏省中医药研究院, departmentName=null, remark=^2.江苏省中医药研究院)]), AuthorCompany(id=1319955843546722306, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=3, ext=[AuthorCompanyExt(id=1319955843555110915, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955843546722306, language=CN, country=null, province=null, city=null, postcode=null, companyName=南京中医药大学附属中西医结合医院, departmentName=null, remark=^3.南京中医药大学附属中西医结合医院)])]), Author(id=1319955844503023640, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, orderNo=5, firstName=null, middleName=null, lastName=null, nameCn=赵帅, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955844591104028, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, authorId=1319955844503023640, language=CN, stringName=赵帅, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,²,³, address=^1.南京大学医院,^2.江苏省中医药研究院,^3.南京中医药大学附属中西医结合医院南京大学医院, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955841785115647, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=1, ext=[AuthorCompanyExt(id=1319955841793504256, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955841785115647, language=CN, country=null, province=null, city=null, postcode=null, companyName=南京大学医院, departmentName=null, remark=^1.南京大学医院)]), AuthorCompany(id=1319955841885777920, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=2, ext=[AuthorCompanyExt(id=1319955841898360833, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955841885777920, language=CN, country=null, province=null, city=null, postcode=null, companyName=江苏省中医药研究院, departmentName=null, remark=^2.江苏省中医药研究院)]), AuthorCompany(id=1319955843546722306, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=3, ext=[AuthorCompanyExt(id=1319955843555110915, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955843546722306, language=CN, country=null, province=null, city=null, postcode=null, companyName=南京中医药大学附属中西医结合医院, departmentName=null, remark=^3.南京中医药大学附属中西医结合医院)])]), Author(id=1319955844654018589, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, orderNo=6, firstName=null, middleName=null, lastName=null, nameCn=刘红权, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=2, ext={CN=AuthorExt(id=1319955844746293281, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, authorId=1319955844654018589, language=CN, stringName=刘红权, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹,²,³, address=^1.南京大学医院,^2.江苏省中医药研究院,^3.南京中医药大学附属中西医结合医院南京大学医院, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319955841785115647, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=1, ext=[AuthorCompanyExt(id=1319955841793504256, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955841785115647, language=CN, country=null, province=null, city=null, postcode=null, companyName=南京大学医院, departmentName=null, remark=^1.南京大学医院)]), AuthorCompany(id=1319955841885777920, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=2, ext=[AuthorCompanyExt(id=1319955841898360833, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955841885777920, language=CN, country=null, province=null, city=null, postcode=null, companyName=江苏省中医药研究院, departmentName=null, remark=^2.江苏省中医药研究院)]), AuthorCompany(id=1319955843546722306, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=3, ext=[AuthorCompanyExt(id=1319955843555110915, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955843546722306, language=CN, country=null, province=null, city=null, postcode=null, companyName=南京中医药大学附属中西医结合医院, departmentName=null, remark=^3.南京中医药大学附属中西医结合医院)])])], keywords=[Keyword(id=1319955844846956578, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, language=CN, orderNo=1, keyword=急性脑梗死), Keyword(id=1319955844905676835, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, language=CN, orderNo=2, keyword=犀角地黄汤), Keyword(id=1319955844968591396, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, language=CN, orderNo=3, keyword=阿加曲班), Keyword(id=1319955845031505957, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, language=CN, orderNo=4, keyword=溶栓), Keyword(id=1319955845094420518, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, language=CN, orderNo=5, keyword=炎症因子), Keyword(id=1319955845161529383, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, language=CN, orderNo=6, keyword=凝血功能), Keyword(id=1319955845228638248, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, language=CN, orderNo=7, keyword=血流动力学)], refs=[Reference(id=1319955845413187626, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[1], rfOrder=0, authorNames=null, journalName=null, refType=null, unstructuredReference=中华医学会神经病学分会,中华医学会神经病学分会脑血管病学组.中国各类主要脑血管病诊断要点2019[J].中华神经科杂志,2019(09)., articleTitle=null, refAbstract=null), Reference(id=1319955845413187627, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[2], rfOrder=1, authorNames=null, journalName=null, refType=null, unstructuredReference=高生伟,李伟荣.阿加曲班联合双抗治疗穿支动脉病变型脑梗死的疗效及安全性评价[J].中国实用神经疾病杂志,2021(06)., articleTitle=null, refAbstract=null), Reference(id=1319955845413187628, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[3], rfOrder=2, authorNames=null, journalName=null, refType=null, unstructuredReference=中华医学会神经病学分会,中华医学会神经病学分会脑血管病学组.中国急性缺血性脑卒中诊治指南2018[J].中华神经科杂志,2018(09)., articleTitle=null, refAbstract=null), Reference(id=1319955845413187629, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[4], rfOrder=3, authorNames=null, journalName=null, refType=null, unstructuredReference=潘思敏,林兴栋,沈志勇.犀角地黄汤对缺血性脑卒中再灌注大鼠模型自噬水平的调节机制分析[J].临床和实验医学杂志,2020(04)., articleTitle=null, refAbstract=null), Reference(id=1319955845413187630, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[5], rfOrder=4, authorNames=null, journalName=null, refType=null, unstructuredReference=杨宁,过伟峰.周仲瑛从瘀热论治缺血性中风急性期的学术思想[J].北京中医,2007(12)., articleTitle=null, refAbstract=null), Reference(id=1319955845413187631, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[6], rfOrder=5, authorNames=null, journalName=null, refType=null, unstructuredReference=周蓓群,俞晓翔,赵玥,王琰萍,吴晓强.阿加曲班治疗急性缺血卒中溶栓后24 h内早期神经功能恶化的疗效观察[J].现代实用医学,2023(07)., articleTitle=null, refAbstract=null), Reference(id=1319955845413187632, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[7], rfOrder=6, authorNames=null, journalName=null, refType=null, unstructuredReference=解静,程琦,刘昳佳,高杉,于春泉.NLRP3炎症小体在动脉粥样硬化中的作用研究进展[J].天津中医药,2020(04)., articleTitle=null, refAbstract=null), Reference(id=1319955845413187633, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[8], rfOrder=7, authorNames=null, journalName=null, refType=null, unstructuredReference=黄传君,赵方正,张才擎.生地黄有效成分梓醇药理作用机制研究进展[J].上海中医药杂志,2017(02)., articleTitle=null, refAbstract=null), Reference(id=1319955845413187634, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[9], rfOrder=8, authorNames=null, journalName=null, refType=null, unstructuredReference=汤佳瑶,黄思莹,武文星,朱悦,郭盛,赵明,段金廒,刘睿.水牛角中含巯基肽类成分的富集及抗氧化、抗炎活性研究[J].中草药,2023(09)., articleTitle=null, refAbstract=null), Reference(id=1319955845417381931, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[10], rfOrder=9, authorNames=null, journalName=null, refType=null, unstructuredReference=冯伟科,郭平.芍药苷药理作用研究进展[J].山东中医杂志,2019(01)., articleTitle=null, refAbstract=null), Reference(id=1319955845417381932, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[11], rfOrder=10, authorNames=null, journalName=null, refType=null, unstructuredReference=Vascular Neurology Committee,Beijing Neuroscience Society,Experts Group of Chinese Consensus on Argatroban for Treatment of Acute Ischemic Stroke.阿加曲班治疗急性缺血性卒中中国专家共识2021[J].中国卒中杂志,2021(09)., articleTitle=null, refAbstract=null), Reference(id=1319955845417381933, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[12], rfOrder=11, authorNames=null, journalName=null, refType=null, unstructuredReference=全柯桦,马琳,潘岳松,杨晓萌,陈玮琪,王伊龙,陈会生.阿加曲班治疗急性缺血性卒中的临床应用[J].中国卒中杂志,2017(09)., articleTitle=null, refAbstract=null), Reference(id=1319955845417381934, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[13], rfOrder=12, authorNames=null, journalName=null, refType=null, unstructuredReference=潘燕,朱艳彬,牟晓梅.超敏C反应蛋白(hs-CRP)在脑梗死中诊断和病情评估的探究[J].中国实验诊断学,2019(06)., articleTitle=null, refAbstract=null), Reference(id=1319955845417381935, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[14], rfOrder=13, authorNames=null, journalName=null, refType=null, unstructuredReference=刘阳欣,赵锋,康秉涛,郭蒙,张洁,韩文,李畅,田欢,王文军,曹慧玲.丹皮酚药理学研究进展[J].陕西中医,2020(04)., articleTitle=null, refAbstract=null), Reference(id=1319955845417381936, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[15], rfOrder=14, authorNames=null, journalName=null, refType=null, unstructuredReference=杨雪梅,胡敏.不同程度脑梗死患者的血清同型半胱氨酸和纤维蛋白原水平及凝血酶原时间与预后的相关性[J].临床与病理杂志,2023(02)., articleTitle=null, refAbstract=null), Reference(id=1319955845417381937, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[16], rfOrder=15, authorNames=null, journalName=null, refType=null, unstructuredReference=脑卒中患者临床神经功能缺损程度评分标准[J].中医药临床杂志,2023(10)., articleTitle=null, refAbstract=null)], funds=[Fund(id=1319955845316718633, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, awardId=2042174824050032642, language=CN, fundingSource=江苏省第六期“333人才”项目, fundOrder=null, country=null)], companyList=[AuthorCompany(id=1319955841785115647, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=1, ext=[AuthorCompanyExt(id=1319955841793504256, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955841785115647, language=CN, country=null, province=null, city=null, postcode=null, companyName=南京大学医院, departmentName=null, remark=^1.南京大学医院)]), AuthorCompany(id=1319955841885777920, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=2, ext=[AuthorCompanyExt(id=1319955841898360833, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955841885777920, language=CN, country=null, province=null, city=null, postcode=null, companyName=江苏省中医药研究院, departmentName=null, remark=^2.江苏省中医药研究院)]), AuthorCompany(id=1319955843546722306, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, xref=3, ext=[AuthorCompanyExt(id=1319955843555110915, tenantId=1146029695717560320, journalId=1315121837170065538, articleId=1319955841525068797, companyId=1319955843546722306, language=CN, country=null, province=null, city=null, postcode=null, companyName=南京中医药大学附属中西医结合医院, departmentName=null, remark=^3.南京中医药大学附属中西医结合医院)])], figs=null, attaches=null, journal=Journal(id=1315120739373908093, delFlag=0, nameCn=中医学报, nameEn=Acta Chinese Medicine, nameHistory1=null, nameHistory2=null, issn=1674-8999, eissn=null, cn=41-1411/R, coden=null, periodic=0, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=8b94oSAFH8bu+kilqGRUOQ==, journalPrice=null, startedYear=null, abbrevIsoEn=Acta Chinese Medicine, journalRemark=null, publicationField=null, createdTime=1791478818030, updatedTime=1791479792022, createdBy=18614031015, updatedBy=13701087609, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Medical and Pharmaceutical Sciences, subjectName=null, subjectCodeEn=Medical and Pharmaceutical Sciences, subjectNameEn=null, picCn=8b94oSAFH8bu+kilqGRUOQ==, picEn=Y56h/oCYJegF4hgM5ASRZw==, jcr=null, cjcr=null, exts=[JournalExt(id=1315124824696017555, language=CN, name=中医学报, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1791479792045, updatedTime=1791479792045, createdBy=13701087609, updatedBy=13701087609, submissionGuidelinesUrl=, submissionAuthorUrl=https://hnzyydx.portal.founderss.cn, submissionEditorUrl=https://journal.ids.fzyun.cn/auth/realms/journal/protocol/openid-connect/auth?client_id=journal-portal&redirect_uri=https%3A%2F%2Fjournal.portal.founderss.cn%2Foauth%2Fcallback&response_type=code&scope=phone+openid+email+profile&state=6c31f9e3-672c-4715-b, submissionReviewUrl=https://hnzyydx.portal.founderss.cn, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1315124824763126420, language=EN, name=Acta Chinese Medicine, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1791479792061, updatedTime=1791479792061, createdBy=13701087609, updatedBy=13701087609, submissionGuidelinesUrl=, submissionAuthorUrl=https://hnzyydx.portal.founderss.cn, submissionEditorUrl=https://journal.ids.fzyun.cn/auth/realms/journal/protocol/openid-connect/auth?client_id=journal-portal&redirect_uri=https%3A%2F%2Fjournal.portal.founderss.cn%2Foauth%2Fcallback&response_type=code&scope=phone+openid+email+profile&state=6c31f9e3-672c-4715-b, submissionReviewUrl=https://hnzyydx.portal.founderss.cn, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1315121837170065538, websiteList=[Website(id=1315346106557518446, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1315121837170065538, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zyxb/CN, language=CN, createTime=1791532549752, createBy=18614031015, updateTime=1791532766964, updateBy=18614031015, name=中医学报-中文, tplId=1146099689490845704, title=中医学报, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1315347175865963357, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=articleTextType, value=kx, createTime=1791532804695, updateTime=1791532804695, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175811437402, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=banner, value=null, createTime=1791532804682, updateTime=1791532804682, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175916295008, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=grayFlag, value=0, createTime=1791532804707, updateTime=1791532804707, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175790465881, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=logo, value=https://castjournals.cast.org.cn/joweb/zyxb/CN/file/pic?fileId=vxJwzD/oKgABLDx+COUqfw==, createTime=1791532804677, updateTime=1791532804677, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175954043746, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=minRunFlag, value=0, createTime=1791532804716, updateTime=1791532804716, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175849186140, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zyxb/CN/file/pic, createTime=1791532804691, updateTime=1791532804691, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175941460833, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=silenceFlag, value=0, createTime=1791532804713, updateTime=1791532804713, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175832408923, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1791532804687, updateTime=1791532804687, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175882740574, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=themeColor, value=null, createTime=1791532804699, updateTime=1791532804699, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347175895323487, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346106557518446, code=themeStyle, value=null, createTime=1791532804702, updateTime=1791532804702, creator=18614031015, updator=18614031015)]), Website(id=1315346107010503292, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1315121837170065538, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zyxb/EN, language=EN, createTime=1791532549860, createBy=18614031015, updateTime=1791532762834, updateBy=18614031015, name=中医学报-英文, tplId=1146101810881728533, title=Acta Chinese Medicine, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1315347133386052431, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=articleTextType, value=kx, createTime=1791532794567, updateTime=1791532794567, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133339915084, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=banner, value=null, createTime=1791532794556, updateTime=1791532794556, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133427995474, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=grayFlag, value=0, createTime=1791532794577, updateTime=1791532794577, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133318943563, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=logo, value=https://castjournals.cast.org.cn/joweb/zyxb/EN/file/pic?fileId=vxJwzD/oKgABLDx+COUqfw==, createTime=1791532794551, updateTime=1791532794551, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133448966996, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=minRunFlag, value=0, createTime=1791532794582, updateTime=1791532794582, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133369275214, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zyxb/EN/file/pic, createTime=1791532794563, updateTime=1791532794563, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133440578387, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=silenceFlag, value=0, createTime=1791532794580, updateTime=1791532794580, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133360886605, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1791532794561, updateTime=1791532794561, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133411218256, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=themeColor, value=null, createTime=1791532794573, updateTime=1791532794573, creator=18614031015, updator=18614031015), WebsiteProps(id=1315347133419606865, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1315346107010503292, code=themeStyle, value=null, createTime=1791532794575, updateTime=1791532794575, creator=18614031015, updator=18614031015)])], journalTitle=中医学报, weixinUrl=null, journalUrl=https://hnzk.publish.founderss.cn/, iacademicId=null, status=1, seqNo=null, journalTitleEn=Acta Chinese Medicine, journalPhotoCn=8b94oSAFH8bu+kilqGRUOQ==, journalPhotoEn=Y56h/oCYJegF4hgM5ASRZw==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zyxb/CN/10.16368/j.issn.1674-8999.2026.01.030, detailUrlEn=https://castjournals.cast.org.cn/joweb/zyxb/EN/10.16368/j.issn.1674-8999.2026.01.030, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zyxb/CN/PDF/10.16368/j.issn.1674-8999.2026.01.030, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zyxb/EN/PDF/10.16368/j.issn.1674-8999.2026.01.030, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1792631596212, fullTextJson=null, articleText=null, reference=null)