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tenantId=1146029695717560320, journalId=1315121837170065538, language=CN, title=基于代谢重编程探讨糖尿病肾脏病气虚血瘀证实质, columnId=null, journalTitle=中医学报, columnName=论著, runingTitle=null, highlight=null, articleAbstract=糖尿病肾脏病(diabetic kidney disease,DKD)是糖尿病患者重要的微血管并发症，可能导致肾功能衰竭。代谢重编程以物质与能量流向失衡为核心，其特征包括线粒体功能障碍、糖酵解增加和脂质代谢异常等。气虚血瘀是DKD的关键病理机制，代谢重编程贯穿于DKD病理演变的整个过程，在其发展中起到推动作用，而DKD的存在也加速了代谢重编程的过程。益气活血化瘀法为DKD的重要治法，通过标本同治，改善线粒体功能，调节代谢平衡，抑制氧化应激，改善肾功能。重塑代谢重编程有助于恢复正常的代谢秩序，从而减缓或逆转DKD的进展。, authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null)}, 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